Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Xiumei Huang"'
Autor:
Lakshmi Prabhu, Matthew Martin, Lan Chen, Özlem Demir, Jiamin Jin, Xiumei Huang, Aishat Motolani, Mengyao Sun, Guanglong Jiang, Harikrishna Nakshatri, Melissa L. Fishel, Steven Sun, Ahmad Safa, Rommie E. Amaro, Mark R. Kelley, Yunlong Liu, Zhong-Yin Zhang, Tao Lu
Publikováno v:
Genes and Diseases, Vol 10, Iss 1, Pp 267-283 (2023)
Market drugs, such as Food and Drug Administration (FDA) or European Medicines Agency (EMA)-approved drugs for specific indications provide opportunities for repurposing for newer therapeutics. This potentially saves resources invested in clinical tr
Externí odkaz:
https://doaj.org/article/c1b0c6c6e2c44a04afeb6c77405f86a9
Autor:
Xiaoyan Zhang, Kezhen Ning, Zhongren Yang, Xiumei Huang, Hongtao Yu, Nana Fu, Xinyuan Qin, Lizhen Hao, Fenglan Zhang
Publikováno v:
BMC Plant Biology, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background The yield and quality of Pugionium cornutum (L.) Gaertn., a healthy, green vegetable with low sugar and high protein contents and high medicinal value, is severely affected by autotoxicity, which is a leading factor in the formati
Externí odkaz:
https://doaj.org/article/71cb8f3a01c1488396142234c8a220ff
Autor:
Jiangwei Wang, Xiaolin Su, Lingxiang Jiang, Matthew W. Boudreau, Lindsay E. Chatkewitz, Jessica A. Kilgore, Kashif Rafiq Zahid, Noelle S. Williams, Yaomin Chen, Shaohui Liu, Paul J. Hergenrother, Xiumei Huang
Publikováno v:
Cancers, Vol 15, Iss 24, p 5844 (2023)
Lung and breast cancers rank as two of the most common and lethal tumors, accounting for a substantial number of cancer-related deaths worldwide. While the past two decades have witnessed promising progress in tumor therapy, developing targeted tumor
Externí odkaz:
https://doaj.org/article/e68fc5c06b6b49fc825f9ed81528a168
Autor:
Soumya Tumbath, Lingxiang Jiang, Xiaoguang Li, Taolan Zhang, Kashif Rafiq Zahid, Ye Zhao, Hao Zhou, Zhijun Yin, Tao Lu, Shu Jiang, Yaomin Chen, Xiang Chen, Yang-Xin Fu, Xiumei Huang
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
NAD(P)H:quinone oxidoreductase 1 (NQO1) is overexpressed in most solid cancers, emerging as a promising target for tumor-selective killing. β-Lapachone (β-Lap), an NQO1 bioactivatable drug, exhibits significant antitumor effects on NQO1-positive ca
Externí odkaz:
https://doaj.org/article/949b1bfe9fef4f57be1db5d9a66f7789
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundArtificial intelligence-assisted colonoscopy (AIAC) has been proposed and validated in recent years, but the effectiveness of clinic application remains unclear since it was only validated in some clinical trials rather than normal conditio
Externí odkaz:
https://doaj.org/article/406d0541cd6f49e18a9d5d5e727e59b0
Autor:
Aishat Motolani, Matthew Martin, Benlian Wang, Guanglong Jiang, Faranak Alipourgivi, Xiumei Huang, Ahmad Safa, Yunlong Liu, Tao Lu
Publikováno v:
Cancers, Vol 15, Iss 19, p 4742 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, with a mere 5-year survival of ~10%. This highlights the urgent need for innovative treatment options for PDAC patients. The nuclear factor κB (NF-κB) is a crucial tran
Externí odkaz:
https://doaj.org/article/a33f8bdcc9f94338aabaff7a7e796e6b
Publikováno v:
PeerJ, Vol 10, p e14436 (2022)
Cynanchum thesioides (Freyn) K. Schum. is an important economic and medicinal plant widely distributed in northern China. WRKY transcription factors (TFs) play important roles in plant growth, development and regulating responses. However, there is n
Externí odkaz:
https://doaj.org/article/931605c03cfc4b0d8275734cacd88787
Autor:
Lingxiang Jiang, Yingchun Liu, Xiaolin Su, Jiangwei Wang, Ye Zhao, Soumya Tumbath, Jessica A. Kilgore, Noelle S. Williams, Yaomin Chen, Xiaolei Wang, Marc S. Mendonca, Tao Lu, Yang-Xin Fu, Xiumei Huang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) have exhibited great promise in the treatment of tumors with homologous recombination (HR) deficiency, however, PARPi resistance, which ultimately recovers DNA repair and cell progress, has becom
Externí odkaz:
https://doaj.org/article/7294b000718d473d9094375b83e0e831
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Neutrophils, the most copious leukocytes in human blood, play a critical role in tumorigenesis, cancer progression, and immune suppression. Recently, neutrophils have attracted the attention of researchers, immunologists, and oncologists because of t
Externí odkaz:
https://doaj.org/article/206a74b079c647989cb2418a94bbdd52
Autor:
Tengteng Yang, Ge Zhao, Yunzhe Liu, Lin Wang, Yubin Gao, Jianmei Zhao, Na Liu, Xiumei Huang, Qingqing Zhang, Junhui Liu, Xiyue Zhang, Junwei Wang, Ying Xu
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Pork is one of the most common foods causing microbial foodborne diseases. Since pork directly enters the market after slaughtering, the control of microbial contamination in the slaughtering processes is the key to ensuring the quality and safety of
Externí odkaz:
https://doaj.org/article/1fe045e77db24184aedaedfbd35375fe