Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Xiulong, Xu"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Many DNA viruses develop various strategies to inhibit cell death to facilitate their replication. However, whether influenza A virus (IAV), a fast-replicating RNA virus, attenuates cell death remains unknown. Here, we report that IAV infect
Externí odkaz:
https://doaj.org/article/2ab463230aee4676807d10cad6331be4
Autor:
Tianmin Wang, Yuan Wen, Bingxu Qian, Fang Tang, Xiaorong Zhang, Xiulong Xu, Yanmin Zhou, Jianjun Dai, Aiqin Wang, Feng Xue
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background The Porcine Epidemic Diarrhea Virus (PEDV) has caused significant economic losses in the global swine industry. As a potential drug for treating diarrhea, the antiviral properties of attapulgite deserve further study. Methods In t
Externí odkaz:
https://doaj.org/article/7ac6a8c0e25e490583fd61a0983a7c8b
Autor:
Jingting Zhang, Yunhan Wu, Yujie Wang, Penggang Liu, Kaituo Liu, Jing Sun, Pinghu Zhang, Xiaoquan Wang, Xiufan Liu, Xiulong Xu
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110424- (2024)
Summary: Cellular cholesterol plays an important role in influenza A virus (IAV) endocytosis and replication. However, how IAV infection regulates cholesterol biosynthesis remains poorly understood. Here, we report that IAV infection activates SREBP2
Externí odkaz:
https://doaj.org/article/a0a649b0acbc4915bad27ec73ba7ca25
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 1697-1712 (2022)
Autophagy plays an important role in defending against invading microbes. However, numerous viruses can subvert autophagy to benefit their replication. Porcine epidemic diarrhoea virus (PEDV) is an aetiological agent that causes severe porcine epidem
Externí odkaz:
https://doaj.org/article/a5e347a229734f60837d4432fe3c365e
Autor:
Tao Ruan, Yuling Sun, Jingting Zhang, Jing Sun, Wei Liu, Richard A. Prinz, Daxin Peng, Xiufan Liu, Xiulong Xu
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Ruan et al. investigate the effect of H5N1 infection on the expression of intercellular junction proteins (E-cadherin, Occludin, Claudin-1, and ZO-1), which they find results in reduced expression of these proteins via activation of TAK1, p38, and ER
Externí odkaz:
https://doaj.org/article/e7c07e1699bf4f599096555982cf68dc
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
DNA damage by genotoxic drugs such as gemcitabine and 5-fluorouracil (5-FU) activates the ataxia telangiectasia, mutated (ATM)-Chk pathway and induces the expression of NKG2D ligands such as the MHC class I-related chain A and B (MICA/B). The mechani
Externí odkaz:
https://doaj.org/article/e5d982dda9bd4ef29e09ecd5920e62a8
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-13 (2021)
Abstract The sonic hedgehog (Shh) pathway is highly activated in a variety of malignancies and plays important roles in tumorigenesis, tumor growth, drug resistance, and metastasis. Our recent study showed that the inhibitors of the Shh pathway such
Externí odkaz:
https://doaj.org/article/0db319dd27bd4cacab61d4a168927c0a
Autor:
Xiuli Li, Ying Zhao, Shumiao Qiao, Min Gu, Ruyi Gao, Zhichuang Ge, Xiulong Xu, Xiaoquan Wang, Jing Ma, Jiao Hu, Shunlin Hu, Xiaowen Liu, Sujuan Chen, Daxin Peng, Xinan Jiao, Xiufan Liu
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The genotype S (G57) H9N2 virus, which first emerged in 2007 with the substitution of the G1-like PB2 gene for F98-like ones, has become the predominant genotype in the past 10 years. However, whether this substitution plays a role in the fitness of
Externí odkaz:
https://doaj.org/article/d3729f7235374da2978f03562fceedf0
Publikováno v:
Cell Reports, Vol 31, Iss 13, Pp 107801- (2020)
Summary: Influenza A virus (IAV) primarily infects the airway and alveolar epithelial cells and disrupts the intercellular junctions, leading to increased paracellular permeability. Although this pathological change plays a critical role in lung tiss
Externí odkaz:
https://doaj.org/article/0ecd16ba06634e22969ba37009e848df
Autor:
Yang Jiao, Yong-guo Zhang, Zhijie Lin, Rong Lu, Yinglin Xia, Chuang Meng, Zhimin Pan, Xiulong Xu, Xinan Jiao, Jun Sun
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Autophagy is a cellular process to clear pathogens. Salmonella enterica serovar Enteritidis (S.E) has emerged as one of the most important food-borne pathogens. However, major studies still focus on Salmonella enterica serovar Typhimurium. Here, we r
Externí odkaz:
https://doaj.org/article/936697a0ee9043398985d7c73deb5b0b