Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Xiuling You"'
Autor:
Lijun Wang, Xiuling You, Dengfeng Ruan, Rui Shao, Hai-Qiang Dai, Weiliang Shen, Guo-Liang Xu, Wanlu Liu, Weiguo Zou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here the authors investigate the role of the TET family of DNA demethylases in mammalian skeletal development. They find that loss of TETs leads to hypermethylation that results in decreased chromatin accessibility of RUNX2 target genes, repressing o
Externí odkaz:
https://doaj.org/article/f99b3da8bdc341b2bb26d25ac7510c69
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and resorption by osteoclasts. These opposite processes allow the accommodation of bones to dynamic
Externí odkaz:
https://doaj.org/article/9443d20570df461ea2868f9c4af00cd3
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Mechanical forces induce bone remodeling, but how bone cells sense mechanical signaling is unclear. Here, the authors show that loss of the mechanotransduction channel Piezo1 in osteoblastic cells impairs osteoclast activity via YAP signaling and col
Externí odkaz:
https://doaj.org/article/d37c4da320be48d0aad1955eb3259e3c
Publikováno v:
Bone research. 10(1)
Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via a balance between bone formation by osteoblasts and resorption by osteoclasts. These opposite processes allow the accommodation of bones to dynamic mechanic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5628194dd9533aeb387ef13c8724ac0c
https://pubmed.ncbi.nlm.nih.gov/35181672
https://pubmed.ncbi.nlm.nih.gov/35181672
Autor:
Lijun Wang, Xiuling You, Dengfeng Ruan, Rui Shao, Hai-Qiang Dai, Weiliang Shen, Guo-Liang Xu, Wanlu Liu, Weiguo Zou
Publikováno v:
Nature communications. 13(1)
The Ten-eleven translocation (TET) family of dioxygenases mediate cytosine demethylation by catalyzing the oxidation of 5-methylcytosine (5mC). TET-mediated DNA demethylation controls the proper differentiation of embryonic stem cells and TET members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c463bfc7d8807cbd64e1dbaa4a3793e7
https://pubmed.ncbi.nlm.nih.gov/35953487
https://pubmed.ncbi.nlm.nih.gov/35953487
Publikováno v:
Fish & Shellfish Immunology. 70:1-12
The major histocompatibility complex class II (MHC II) molecules play a vital role in adaptive immune response through presenting antigenic peptides to CD4+ T lymphocytes. To accomplish this physiologic function, the MHC class II-associated invariant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e913e07f016aa98a3a4a6bf91808f7d
https://doi.org/10.1016/j.fsi.2017.08.042
https://doi.org/10.1016/j.fsi.2017.08.042
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Wolff’s law and the Utah Paradigm of skeletal physiology state that bone architecture adapts to mechanical loads. These models predict the existence of a mechanostat that links strain induced by mechanical forces to skeletal remodeling. However, ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5860882112f61f52e9fb188cfafdda8
https://pubmed.ncbi.nlm.nih.gov/31941964
https://pubmed.ncbi.nlm.nih.gov/31941964
Publikováno v:
Bone Research
Bone Research, Vol 6, Iss 1, Pp 1-11 (2018)
Bone Research, Vol 6, Iss 1, Pp 1-11 (2018)
The skeleton is a dynamic organ that is constantly remodeled. Proteins secreted from bone cells, namely osteoblasts, osteocytes, and osteoclasts exert regulation on osteoblastogenesis, osteclastogenesis, and angiogenesis in a paracrine manner. Osteob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72877ce9bb4a5a9590409a6c4594c2c9
https://doi.org/10.1038/s41413-018-0019-6
https://doi.org/10.1038/s41413-018-0019-6
Autor:
Xiuyu Li, Zhiyong Liao, Hejun Du, Xingguo Zhang, Yitian Gao, Mingjiang Wu, Xiuling You, Liu Liu, Haibing Tong, Dongsong Nie
Publikováno v:
Fishshellfish immunology. 72
Interferon-γ-inducible lysosomal thiol reductase (GILT) plays an important role in the major histocompatibility complex-restricted antigen processing of endocytosed proteins via catalyzing the disulfide bond reduction in the endocytic pathway. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fbff22181901e8330c9081e0aa4b17
https://pubmed.ncbi.nlm.nih.gov/29133251
https://pubmed.ncbi.nlm.nih.gov/29133251
Publikováno v:
Medicine and Biopharmaceutical.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c58b42ccfdc313aab5091a4bc078897
https://doi.org/10.1142/9789814719810_0137
https://doi.org/10.1142/9789814719810_0137