Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Xiulan, Lai"'
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Patients with chronic myeloid leukemia (CML) who receive tyrosine kinase inhibitors (TKIs) have been known to achieve treatment-free remission (TFR) upon discontinuing treatment. However, the underlying mechanisms of this phenomenon remain i
Externí odkaz:
https://doaj.org/article/ba0df6faec0e4ac8a28ad0eb284bf469
Autor:
Rujing Zhao, Xiulan Lai
Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 1, Pp 656-682 (2023)
The emergence and growth of drug-resistant cancer cell subpopulations during anti-cancer treatment is a major challenge for cancer therapies. Combination therapies are usually applied for overcoming drug resistance. In the present paper, we explored
Externí odkaz:
https://doaj.org/article/6eceb200e8584ece9f1cc2488449569b
Autor:
Shizhao Ma, Yi Chen, Xiulan Lai, Guanghua Lan, Yuhua Ruan, Zhiyong Shen, Qiuying Zhu, Shuai Tang
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270525 (2022)
To control the HIV/AIDS epidemics in Guangxi Zhuang Autonomous Region in China, Guangxi government launched the 5-year Guangxi AIDS Conquering Project (GACP, Phase I: 2010-2014, Phase II: 2015-2020). In the project, three measures are implemented, su
Externí odkaz:
https://doaj.org/article/d8639e3ee0694708a7ba3550c0705228
Autor:
Wei Wang, Xiulan Lai
Publikováno v:
Mathematical Biosciences and Engineering, Vol 17, Iss 2, Pp 1442-1449 (2020)
Recently, it has been proved that for the diffusive viral infection model with cell-to-cell infection, the virus-free steady state E0 is globally attractive when the basic reproduction number R0 < 1, and the virus is uniformly persistent if R0 > 1. H
Externí odkaz:
https://doaj.org/article/7e04d9457c9c426ab8ddf5de6a734f47
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Endoplasmic reticulum (ER) stress is implicated in the pathogenesis of many diseases, including myocardial ischemia/reperfusion injury. We hypothesized that human umbilical cord mesenchymal stromal cells derived extracellular vesicles (HuMSC-EVs) cou
Externí odkaz:
https://doaj.org/article/5286b61672ea4ec4b09a38982da1e4dd
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231499 (2020)
Drug resistance is a primary obstacle in cancer treatment. In many patients who at first respond well to treatment, relapse occurs later on. Various mechanisms have been explored to explain drug resistance in specific cancers and for specific drugs.
Externí odkaz:
https://doaj.org/article/d5682fab55c5443287b38810fecb4283
Publikováno v:
Mathematical Methods in the Applied Sciences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38f6b77a0f1802a84b11c189d1407a5c
https://doi.org/10.1002/mma.9256
https://doi.org/10.1002/mma.9256
Autor:
Rujing Zhao, Xiulan Lai
Publikováno v:
Mathematical Biosciences and Engineering. 20:656-682
The emergence and growth of drug-resistant cancer cell subpopulations during anti-cancer treatment is a major challenge for cancer therapies. Combination therapies are usually applied for overcoming drug resistance. In the present paper, we explored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2fde5e0e63e3ae46aea4ca85cbf2fd9
https://doi.org/10.3934/mbe.2023030
https://doi.org/10.3934/mbe.2023030
Publikováno v:
Journal of Mathematical Biology. 86
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a76484131616afc653bb6cc56b43a401
https://doi.org/10.1007/s00285-023-01872-1
https://doi.org/10.1007/s00285-023-01872-1
Autor:
Avner Friedman, Xiulan Lai
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192449 (2018)
Oncolytic virus (OV) is a replication competent virus that selectively invades cancer cells; as these cells die under the viral burden, the released virus particles proceed to infect other cancer cells. Oncolytic viruses are designed to also be able
Externí odkaz:
https://doaj.org/article/2813377438ad476b856a4ac9aa75e76d