Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Xiuju Lu"'
Publikováno v:
Journal of Virology. 80:6048-6055
The murine cytomegalovirus (MCMV) protein m4/gp34 is unique among known viral genes that target the major histocompatibility complex (MHC) class I pathway of antigen presentation in the following two ways: it is found in association with class I MHC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf07620eb6ff71a5bdfe7e098f10e97
https://doi.org/10.1128/jvi.00534-06
https://doi.org/10.1128/jvi.00534-06
Autor:
Xiuju Lu, Jonathan W. Yewdell
Publikováno v:
Nature Immunology. 13:526-528
Immunosurveillance monitors subversion of the endoplasmic reticulum aminopeptidase ERAAP. ERAAP-deficient cells are killed by T cells that recognize nonclassical major histocompatibility complex class I Qa-1 molecules presenting peptides generated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b30bfed8ad8ac9a2c692f903923a56
https://doi.org/10.1038/ni.2306
https://doi.org/10.1038/ni.2306
Autor:
Xiuju Lu, Alexandre David, Jack R. Bennink, Yetao Jin, Rajat Varma, Jonathan W. Yewdell, Heather D. Hickman, James S. Gibbs, Brian P. Dolan, David M. Kranz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(38)
Sensitivity is essential in CD8+ T-cell killing of virus-infected cells and tumor cells. Although the affinity of the T-cell receptor (TCR) for antigen is relatively low, the avidity of T cell-antigen–presenting cell interactions is greatly enhance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07059b042a28f40def9bc9d7c8343ffc
https://pubmed.ncbi.nlm.nih.gov/22949678
https://pubmed.ncbi.nlm.nih.gov/22949678
Autor:
Jack R. Bennink, Xiuju Lu, James S. Gibbs, Christopher B. Brooke, Robert L. Modlin, Wanqiu Hou, Jonathan W. Yewdell, Devika Roy
Publikováno v:
Blood. 119(13)
Surprisingly little is known about the interaction of human blood mononuclear cells with viruses. Here, we show that monocytes are the predominant cell type infected when peripheral blood mononuclear cells are exposed to viruses ex vivo. Remarkably,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec58ebd36f8c4c3f33252ed1f0b9405d
https://pubmed.ncbi.nlm.nih.gov/22310910
https://pubmed.ncbi.nlm.nih.gov/22310910
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::584818575c791ba6a5c4d57b3b904136
https://doi.org/10.1096/fasebj.22.1_supplement.1067.14
https://doi.org/10.1096/fasebj.22.1_supplement.1067.14
Compared to other organs, murine cytomegalovirus (MCMV) replication in the salivary gland is uniquely resistant to CD8 T-cell control. The contribution of viral genes that interfere with antigen presentation (VIPRs) to this resistance was assessed us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65766ca7cfef5910308847a63c8df42b
https://europepmc.org/articles/PMC1440476/
https://europepmc.org/articles/PMC1440476/
Publikováno v:
The Journal of Immunology. 192:194.1-194.1
The immunological response to cancer and other diseases depends on the interplay between the innate and adaptive immune systems. CD4 T helper cells are key modulators of immune responses. As an intermediate between the innate and adaptive systems, CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae429061c6f6ec00fbc4aa56f9a3e01d
https://doi.org/10.4049/jimmunol.192.supp.194.1
https://doi.org/10.4049/jimmunol.192.supp.194.1
Publikováno v:
Molecular Immunology. 51:37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c07e7760ed445c72bf6b06b78a22495e
https://doi.org/10.1016/j.molimm.2012.02.105
https://doi.org/10.1016/j.molimm.2012.02.105
Viral Infection Triggers Rapid Differentiation of Human Blood Monocytes into Dendritic Cells (45.12)
Autor:
Wanqiu Hou, James Gibbs, Xiuju Lu, Christopher Brooke, Devika Roy, Robert Modlin, Jack Bennink, Jonathan Yewdell
Publikováno v:
The Journal of Immunology. 188:45.12-45.12
Viruses post a constant threat of human existence. Although human immune system plays a central role in recognizing and eradicating pathogens, how it responds to virus infection remains unclear. Here we show that monocytes make up the majority of a w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b119da4316630f66be5a8039eb1f733f
https://doi.org/10.4049/jimmunol.188.supp.45.12
https://doi.org/10.4049/jimmunol.188.supp.45.12
Autor:
Xiaoying S. Zhong, John H. Winston, Xiuju Luo, Kevin T. Kline, Syed Z. Nayeem, Yingzi Cong, Tor C. Savidge, Roderick H. Dashwood, Don W. Powell, Qingjie Li
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 1, Pp 65-78 (2018)
Early life adversity is considered a risk factor for the development of gastrointestinal diseases, including inflammatory bowel disease. We hypothesized that early life colonic inflammation causes susceptibility to aggravated overexpression of interl
Externí odkaz:
https://doaj.org/article/b3e399dbf4df4c328cf6dd613953469f