Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Xiujie Yuan"'
The development of chimeric antigen receptor T-cells against CD70 for renal cell carcinoma treatment
Autor:
Qinghui Xiong, Haiying Wang, Qiushuang Shen, Yan Wang, Xiujie Yuan, Guangyao Lin, Pengfei Jiang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract In this study, we investigated CD70 as a promising target for renal cell carcinoma (RCC) therapy and developed a potent chimeric antigen receptor T (CAR-T) cells for potential clinical testing. CD70, found to be highly expressed in RCC tumor
Externí odkaz:
https://doaj.org/article/032b207c4faf437da325568ff4a7d0bd
Autor:
Xi Sun, Qiaomei He, Jun Yang, Andi Wang, Fang Zhang, Huiying Qiu, Kun Zhou, Pengran Wang, Xiaodan Ding, Xiujie Yuan, Huajun Li, Yan Zhang, Xianmin Song
Publikováno v:
Cell Transplantation, Vol 30 (2021)
Acute graft-versus-host disease (aGVHD) is one of the most common complications of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Janus kinase (JAK) inhibitors are considered as reliable and promising agents for patients with aGVHD.
Externí odkaz:
https://doaj.org/article/e83e7528d9404c7eaca7f2030c30fb67
Autor:
Peipei Zhou, Xiaodan Ding, Xiaoling Wan, Lulu Liu, Xiujie Yuan, Wei Zhang, Xinhui Hui, Guangxun Meng, Hui Xiao, Bin Li, Jin Zhong, Fajian Hou, Lihwen Deng, Yan Zhang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
MLL5 is an essential epigenetic modifier involved in cell cycle progression, chromatin architecture and hematopoiesis. Here the authors establish that MLL5 suppresses the innate immune response in a murine model of virus infection by targeting and pr
Externí odkaz:
https://doaj.org/article/e70d4a2c123b46d1aff993ffe9991d7e
Autor:
Lulu Liu, Xiaoling Wan, Peipei Zhou, Xiaoyuan Zhou, Wei Zhang, Xinhui Hui, Xiujie Yuan, Xiaodan Ding, Ruihong Zhu, Guangxun Meng, Hui Xiao, Feng Ma, He Huang, Xianmin Song, Bin Zhou, Sidong Xiong, Yan Zhang
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-16 (2018)
Abstract Background Adenosine triphosphate (ATP)-dependent chromatin remodeling SWI/SNF-like BAF and PBAF complexes have been implicated in the regulation of stem cell function and cancers. Several subunits of BAF or PBAF, including BRG1, BAF53a, BAF
Externí odkaz:
https://doaj.org/article/d7d99fa0a3434e59b227a1e2bcb032c4
Autor:
Xiaodan Ding, Wei Jiang, Peipei Zhou, Lulu Liu, Xiaoling Wan, Xiujie Yuan, Xizi Wang, Miao Chen, Jun Chen, Jing Yang, Chao Kong, Bin Li, Chao Peng, Catherine C L Wong, Fajian Hou, Yan Zhang
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145023 (2015)
Mixed lineage leukemia 5 (MLL5) protein is a trithorax family histone 3 lysine 4 (H3K4) methyltransferase that regulates diverse biological processes, including cell cycle progression, hematopoiesis and cancer. The mechanisms by which MLL5 protein st
Externí odkaz:
https://doaj.org/article/a2aff35a16964a9588beeb1d8ab80a38
Publikováno v:
Hydrology, Vol 4, Iss 2, p 29 (2017)
Precipitation data from nine meteorological stations in arid oases of Hexi Corridor, northwest China during 1970–2012 were analyzed to detect trends in precipitation and Standardized Precipitation Index (SPI) at multiple time scales using linear re
Externí odkaz:
https://doaj.org/article/71e7aed132aa43fe9ac4af05c20d9bea
Autor:
Huajun Li, Huiying Qiu, Jun J. Yang, Xiujie Yuan, Kun Zhou, Xiaodan Ding, Andi Wang, Xi Sun, Pengran Wang, Xianmin Song, Fang Zhang, Yan Zhang, Qiaomei He
Publikováno v:
Cell Transplantation
Cell Transplantation, Vol 30 (2021)
Cell Transplantation, Vol 30 (2021)
Acute graft-versus-host disease (aGVHD) is one of the most common complications of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Janus kinase (JAK) inhibitors are considered as reliable and promising agents for patients with aGVHD.
Autor:
Lih-Wen Deng, Peipei Zhou, Lulu Liu, Xiaodan Ding, Guangxun Meng, Xinhui Hui, Bin Li, Fajian Hou, Xiujie Yuan, Jin Zhong, Hui Xiao, Xiaoling Wan, Wei Zhang, Yan Zhang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
Trithorax group protein MLL5 is an important epigenetic modifier that controls cell cycle progression, chromatin architecture maintenance, and hematopoiesis. However, whether MLL5 has a role in innate antiviral immunity is largely unknown. Here we sh
Publikováno v:
Journal of Physics: Conference Series. 1533:032063
With the continuous and rapid development of the economy and society and the steady improvement of the living standards of the people, the intelligentization of rural management has become a new concept and new path to build a co-construction and sha
Autor:
Peipei Zhou, Xinhui Hui, Fang-Fang Yu, Xiaoling Wan, Qiaomei He, Ruihong Zhu, Yuanhua Liu, Xianmin Song, Wei Zhang, Qibin Leng, Johan Auwerx, Pei Hao, Xiujie Yuan, Yan Zhang, Yingxi Zhao, Na Zhang, Lulu Liu, Xiaodan Ding
Publikováno v:
Blood advances. 3(4)
Enhanced understanding of normal and malignant hematopoiesis pathways should facilitate the development of effective clinical treatment strategies for hematopoietic malignancies. Nuclear receptor corepressor 1 (NCoR1) has been implicated in transcrip