Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Xiuhua Su"'
Autor:
Xiaoran Bai, Fei Lu, Shuying Li, Zhe Zhao, Nana Wang, Yanan Zhao, Guangxin Ma, Fan Zhang, Xiuhua Su, Dongmei Wang, Jingjing Ye, Peng Li, Chunyan Ji
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Cuproptosis is a newly defined form of programmed cell death that relies on mitochondria respiration. Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis and metastasis. However, whether cuproptosis-related lncRNAs are involved
Externí odkaz:
https://doaj.org/article/4740cedbe5cc4052b6a7f169e00466e3
Autor:
Dongmei Wang, Tao Sun, Yuan Xia, Zhe Zhao, Xue Sheng, Shuying Li, Yuechan Ma, Mingying Li, Xiuhua Su, Fan Zhang, Peng Li, Daoxin Ma, Jingjing Ye, Fei Lu, Chunyan Ji
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract CCAAT/enhancer binding protein α (C/EBPα) regulates myeloid differentiation, and its dysregulation contributes to acute myeloid leukaemia (AML) progress. Clarifying its functional implementation mechanism is of great significance for its f
Externí odkaz:
https://doaj.org/article/791f92cacbfa415897c5db9139cb9b7a
Autor:
Meng Li, Mingying Li, Yuan Xia, Guosheng Li, Xiuhua Su, Dongmei Wang, Jingjing Ye, Fei Lu, Tao Sun, Chunyan Ji
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-12 (2022)
Abstract Methyltransferase-like protein 3 (METTL3) plays critical roles in acute myeloid leukemia (AML) progression, however, the mechanism of abnormal overexpression of METTL3 in AML remain elusive. In the current study, we uncovered that Yin Yang 1
Externí odkaz:
https://doaj.org/article/2f3a296bc43949cc9fc4c1cb9469d495
Autor:
Xiuhua Su, Tao Sun, Meng Li, Yuan Xia, Mingying Li, Dongmei Wang, Fei Lu, Jingjing Ye, Chunyan Ji
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Background Regulatory T cells (Tregs) induce immune responses and may contribute to immune escape in tumors. Accumulation of Tregs in tumors represents a critical barrier to anti-tumor immunity and immunotherapy. However, conflicting results
Externí odkaz:
https://doaj.org/article/d1207f3eee40463f8f7f7007a588c03c
Autor:
Xiuhua Su, Guangxin Ma, Xiaoran Bai, Juan Zhang, Mingying Li, Fan Zhang, Tao Sun, Daoxin Ma, Fei Lu, Chunyan Ji
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies in adults. The tumor microenvironment (TME) has a critical effect on AML occurrence, recurrence, and progression. The gene feline leukemia virus subgroup C cellular rec
Externí odkaz:
https://doaj.org/article/1a6af02f31f2428288e1ecf5c8f87a35
Autor:
Yuechen Luo, Changlu Xu, Bing Wang, Qing Niu, Xiuhua Su, Yingnan Bai, Shuxian Zhu, Chunxiao Zhao, Yunyan Sun, Jiali Wang, Maolan Liu, Xiaolei Sun, Ge Song, Haidong Cui, Xiaoli Chen, Huifang Huang, Haikun Wang, Mingzhe Han, Erlie Jiang, Lihong Shi, Xiaoming Feng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Human Treg cells are central to immune tolerance, yet their heterogeneity and differentiation remain incompletely understood. Here the authors perform single-cell RNA and T cell receptor sequencing to resolve Treg cells from healthy individuals and p
Externí odkaz:
https://doaj.org/article/7942edb4231e4783bfa50aec2783e956
Autor:
Mingying Li, Jingjing Ye, Yuan Xia, Meng Li, Guosheng Li, Xiang Hu, Xiuhua Su, Dongmei Wang, Xin Zhao, Fei Lu, Jingxin Li, Daoxin Ma, Tao Sun, Chunyan Ji
Publikováno v:
Leukemia. 36:2586-2595
Chemoresistant leukemia relapse is one of the most common causes of death for acute myeloid leukemia (AML) patients and the homing/engraftment in bone marrow (BM) are crucial steps for AML cells to acquire chemoresistance by interacting with stromal
Autor:
Yuan Xia, Tao Sun, Guosheng Li, Mingying Li, Dongmei Wang, Xiuhua Su, Jingjing Ye, Chunyan Ji
Publikováno v:
Leukemia.
To determine the overall tumor microenvironment (TME), characteristics, and transition mechanisms in primary central nervous system lymphoma (PCNSL), we performed spatial transcriptomics and matched the corresponding single-cell sequencing data of PC
Autor:
Qiuhui Jiang, Feng Lin, Zhifeng Li, Hongpeng Duan, Chong Jiang, Xingxing Yu, Caiyan Wang, Li Zhang, Xiuhua Sun, Jie Zha, Long Liu, Zhijuan Lin, Bing Xu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Follicular lymphoma (FL) is an immune-responsive tumor with spontaneous remission. T cells play a pivotal role in the anti-lymphoma immune response. However, the dynamics of T cells during treatment, their impact on FL clinical outcomes, and
Externí odkaz:
https://doaj.org/article/ae5af0df550a4f47bc1e8799bfd87d26
Autor:
Jialin Wei, Yi He, Huaizhu Wu, Qianqian Wang, Sizhou Feng, Mei Wang, Xiaolei Pei, Weihua Zhai, Erlie Jiang, Qiaoling Ma, Xiuhua Su, Christie M. Ballantyne, Mingzhe Han, R L Zhang, Yong Huang, Xiaoming Feng, Donglin Yang, Aiming Pang
Publikováno v:
Immunology
CD11c is a canonical dendritic cell (DC) marker with poorly defined functions in the immune system. Here, we found that blocking CD11c on human peripheral blood mononuclear cell‐derived DCs (MoDCs) inhibited the proliferation of CD4+ T cells and th