Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Xiufeng Zhong"'
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103525- (2024)
Leber’s congenital amaurosis (LCA) is a complex inherited retinal dystrophy characterized by severe vision loss and even blindness early in life, caused by more than 38 genes. Variations in RDH12 were found to be responsible for LCA. We successfull
Externí odkaz:
https://doaj.org/article/8096dd587bfc4be280df4875850cc7db
Publikováno v:
Stem Cell Research, Vol 72, Iss , Pp 103200- (2023)
Retinoblastoma (RB) is a common intraocular malignancy mostly caused by variation of the tumour suppressor gene RB1. In this study, we successfully generated two induced pluripotent stem cell (iPSC) lines from an infant with non-heritable RB. Both ce
Externí odkaz:
https://doaj.org/article/d6ec8cff4da1478f93aece41d3337dfb
Autor:
Linyan Zhang, Xinyu Liu, Mingwei Huang, Ping Xu, Yanting Lai, Yafen Liu, Xiufeng Zhong, Songshan Li, Xiaoyan Ding
Publikováno v:
Stem Cell Research, Vol 65, Iss , Pp 102937- (2022)
X-linked juvenile retinoschisis (XLRS), caused by the mutation of RS1 gene, is one of the most common causes of macular degeneration for male adolescents. The mutations and clinical manifestations of the disease are diverse. Neither the relationship
Externí odkaz:
https://doaj.org/article/304ea977cf3a45bb8edb10c4d84868db
Autor:
Jing Zhou, Miguel Flores-Bellver, Jianbo Pan, Alberto Benito-Martin, Cui Shi, Onyekwere Onwumere, Jason Mighty, Jiang Qian, Xiufeng Zhong, Tasmim Hogue, Baffour Amponsah-Antwi, Linda Einbond, Rajendra Gharbaran, Hao Wu, Bo-Juen Chen, Zhiliang Zheng, Tatyana Tchaikovskaya, Xusheng Zhang, Hector Peinado, Maria Valeria Canto-Soler, Stephen Redenti
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The mechanisms underlying retinal development have not been completely elucidated. Extracellular vesicles (EVs) are novel essential mediators of cell-to-cell communication with emerging roles in developmental processes. Nevertheless, the ide
Externí odkaz:
https://doaj.org/article/074c29b73ad24c44b022f592b4bba8d1
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102913- (2022)
PROM1-related retinal dystrophy (PROM1-RD) is a group of hereditary retinal disorder characterized by the progressive damage of the photoreceptors. We generated and identified two induced pluripotent stem cell (iPSC) lines carrying homozygous or hete
Externí odkaz:
https://doaj.org/article/2430c53328f6493f8e28e597238a7b0d
Autor:
Rong Ning, Dandan Zheng, Bingbing Xie, Guanjie Gao, Jinhai Xu, Ping Xu, Yuan Wang, Fuhua Peng, Bin Jiang, Jian Ge, Xiufeng Zhong
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Müller glial cells (MGCs) play important roles in human retina during physiological and pathological conditions. However, the development process of human MGCs in vivo remains unclear, and how to obtain large numbers of human MGCs with high quality
Externí odkaz:
https://doaj.org/article/073ac19792d94d9c9072a733c8aacf12
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Stem cell-based cell therapies are considered to be promising treatments for retinal disorders with dysfunction or death of photoreceptors. However, the enrichment of human photoreceptors suitable for transplantation has been highly challenging so fa
Externí odkaz:
https://doaj.org/article/e01e2b2bf3604588b99b8757805ccf39
Autor:
Zhuolin Chen, Fuhua Peng, Jia Liu, Bingbing Xie, Ping Xu, Zhouqing Gan, Min Li, Li Xu, Xiufeng Zhong
Publikováno v:
Stem Cell Research, Vol 45, Iss , Pp - (2020)
CLCN2-related leukoencephalopathy (CC2L) is a rare disease due to autosomal recessive loss-of-function mutations in CLCN2 gene. We generated an induced pluripotent stem cell (iPSC) line (SKLOi001-A) from urine cells isolated from a CC2L patient carry
Externí odkaz:
https://doaj.org/article/4d72de2131f848cebecc493e54e6edd1
Publikováno v:
BMC Pediatrics, Vol 18, Iss 1, Pp 1-4 (2018)
Abstract Background Wolfram syndrome (WS), caused by mutations of the Wolfram syndrome 1 (WFS1) gene on chromosome 4p16.1, is an autosomal recessive disorder characterized by diabetes insipidus (DI), neuro-psychiatric disorders, hearing deficit, and
Externí odkaz:
https://doaj.org/article/345a5e02e4704407b8bbdb17879e839f
Autor:
Guilan Li, Guanjie Gao, Panfeng Wang, Xiaojing Song, Ping Xu, Bingbing Xie, Tiancheng Zhou, Guangjin Pan, Fuhua Peng, Qingjiong Zhang, Jian Ge, Xiufeng Zhong
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
RPE65-associated Leber congenital amaurosis (LCA) is one of highly heterogeneous, early onset, severe retinal dystrophies with at least 130 gene mutation sites identified. Their pathogenicity has not been directly clarified due to lack of diseased ce
Externí odkaz:
https://doaj.org/article/e47c40e1a74841b29aed2cf9215f079c