Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Xiudong Ding"'
Autor:
Ying Jiang, Xinqiang Zhang, Bo Wang, Liping Tang, Xin Liu, Xiudong Ding, Yueming Dong, Hong Lei, Di Wang, Huicheng Feng
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Background Cell subsets differentially modulate host immune responses to Mycobacterium tuberculosis (MTB) infection. However, the nature and functions of these subsets against osteoarticular tuberculosis (OTB) are unclear. Here, we aimed to
Externí odkaz:
https://doaj.org/article/a8ff9f2ef337405f90ab3d1817fdc224
Autor:
Yinliang Qi, Xiudong Ding, Kun Wang, Pingzhen Yan, Xinxin Guo, Shiwei Ma, Mingfei Xiao, Pengrui Sun, Siyu Liu, Yunlei Hou, Yanfang Zhao
Publikováno v:
New Journal of Chemistry. 46:9470-9485
A series of new biaryloxazolidinone derivatives has been designed and synthesized using the combination principle and blocking metabolic site to improve their antibacterial activity and stability.
Autor:
Yunlei Hou, Xiudong Ding, Zhanfeng Gao, Siyu Liu, Sicong Xu, Zhiwei Li, Jia Jiang, Ruixi Fan, Tong Chen, Yanfang Zhao, Hengzhi Lu
Publikováno v:
Letters in Drug Design & Discovery. 20
Background: In this article, a series of novel oxazolidinone derivatives containing dithiocarbamate moieties have been designed and synthesized. Methods: Their antibacterial activities were measured against Staphylococcus aureus, vancomycin-resistant
Publikováno v:
Japanese Journal of Infectious Diseases. 74:245-248
Through our previous work, we have identified that novel oxazolidinone structures, the biaryloxazolidinone analogues containing a hydrazone moiety, act as promising antibacterial agents against gram-positive bacterial strains. Based on this active st
Autor:
Xiudong Ding, Zhanfeng Gao, Siyu Liu, Yu Wang, Shihui Wang, Sicong Xu, Zhiwei Li, Jia Jiang, Ruixi Fan, Tong Chen, Yanfang Zhao, Hengzhi Lu, Yunlei Hou
Publikováno v:
SSRN Electronic Journal.
Autor:
Zengkui Yan, Xue Mei, Ying Jiang, Jing Zhou, Yinghui Chai, Xiudong Ding, Xin Liu, Hong Lei, Yueming Dong
Publikováno v:
Microbes and Infection. 24:104893
BACKGROUND There is an abundant link between the gut microbiota and human health and it plays a critical role in the clinic. It is recognized that microbial dysregulation contributes to the pathogenesis of tuberculosis (TB), but the underlying mechan
Publikováno v:
Bioorganicmedicinal chemistry letters. 32
A series of novel oxazolidinone derivatives with nitrogen-containing fused heterocyclic moiety were designed and synthesized in this article. Their antibacterial activities were measured against S. aureus, MRSA and MSSA by MIC assay. Most of them exh
Publikováno v:
Chemical Research in Chinese Universities. 34:51-56
A series of novel oxazolidinone derivatives containing nitro heteroaromatic moiety was synthesized and characterized by means of 1H NMR and MS spectra. All target compounds were evaluated for their in vitro antibac-terial activities against S.au 2921
Autor:
Yinliang Qi, Yifeng Yang, Yanfang Zhao, Yingxiu Li, Xiudong Ding, Mingze Qin, Lu Sun, Feng Hu, Yajing Liu, Yachuang Wu
Publikováno v:
European Journal of Medicinal Chemistry. 185:111781
We previously discovered a series of novel biaryloxazolidinone analogues bearing a hydrazone moiety with potent antibacterial activity. However, the most potent compound OB-104 exhibited undesirable chemical and metabolic instability. Herein, novel b
Autor:
Xue Zhang, Yanfang Zhao, Sicong Xu, Xiudong Ding, Chu Wang, Hong Lei, Yifeng Yang, Yachuang Wu
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(3)
Novel biaryloxazolidinone derivatives containing a rhodanine or thiohydantoin moiety were designed, synthesized and evaluated for their antibacterial activity. The key compounds 7 and 9 were synthesized by the knoevenagel condensation of intermediate