Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Xiu-wu Pan"'
Autor:
Da Xu, LI Zuo, Wang Zhou, Yu-Qi Wang, Wen-Jin Chen, Ke-Qin Dong, Jia-Xin Chen, Wei-Jie Chen, Wen-Yan Li, Zi-Chang Liu, Zheng-Yu Jiang, Yi-Fan Tang, Yu-Xuan Qin, Lin-Hui Wang, Xiu-Wu Pan, Xin-Gang Cui
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Background Tertiary lymphoid structures (TLSs) serve as organized lymphoid aggregates that influence immune responses within the tumor microenvironment. This study aims to investigate the characteristics and clinical significance of TLSs and tumor-in
Externí odkaz:
https://doaj.org/article/a822db8f99ba4850b4ab5171fa2903aa
Autor:
Xiu-wu Pan, Wen-jin Chen, Da Xu, Wen-bin Guan, Lin Li, Jia-xin Chen, Wei-jie Chen, Ke-qin Dong, Jian-qing Ye, Si-shun Gan, Wang Zhou, Xin-gang Cui
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108370- (2023)
Summary: Previous bulk RNA sequencing or whole genome sequencing on clear cell renal cell carcinoma (ccRCC) subtyping mainly focused on ccRCC cell origin or the complex tumor microenvironment (TME). Based on the single-cell RNA sequencing (scRNA-seq)
Externí odkaz:
https://doaj.org/article/778c05f700f34d5cbdde9e7a39873011
Autor:
Wen-jin Chen, Ke-qin Dong, Xiu-wu Pan, Si-shun Gan, Da Xu, Jia-xin Chen, Wei-jie Chen, Wen-yan Li, Yu-qi Wang, Wang Zhou, Brian Rini, Xin-gang Cui
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Tumor growth, metastasis and therapeutic response are believed to be regulated by the tumor and its microenvironment (TME) in advanced renal cell carcinoma (RCC). However, the mechanisms underlying genomic, transcriptomic and epigenetic alte
Externí odkaz:
https://doaj.org/article/d2a358035a5a4a40aeec5e85972cefbd
Autor:
Zhilin Hu, Xiaoyan Yu, Rui Ding, Ben Liu, Chuanjia Gu, Xiu-Wu Pan, Qiaoqiao Han, Yuerong Zhang, Jie Wan, Xin-Gang Cui, Jiayuan Sun, Qiang Zou
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Activation of STING signaling in DCs promotes antitumor immunity. Aerobic glycolysis is a metabolic hallmark of activated DCs, but how the glycolytic pathway intersects with STING signaling in tumor-infiltrating DCs remains elusive. Here, we show tha
Externí odkaz:
https://doaj.org/article/04ba41c004c44dc19b8ab43080681565
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Ample evidence indicates that the development and progression of renal cell carcinoma (RCC) are complex pathological processes involving interactions between tumor cells, immune cells and stromal components. Tumor infiltrated immune cells determine w
Externí odkaz:
https://doaj.org/article/eaa325681c3f46f488ad53a96a3a4e64
Autor:
Wen-jin Chen, Hao Cao, Jian-wei Cao, Li Zuo, Fa-jun Qu, Da Xu, Hao Zhang, Hai-yi Gong, Jia-xin Chen, Jian-qing Ye, Si-shun Gan, Wang Zhou, Da-wei Zhu, Xiu-Wu Pan, Xin-gang Cui
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Non-clear renal cell carcinomas (nccRCCs) are less frequent in kidney cancer with histopathological heterogeneity. A better understanding of the tumor biology of nccRCC can provide more effective treatment paradigms for different subtypes. T
Externí odkaz:
https://doaj.org/article/cb6fa662dd4e457ab9e5f8192511f2ec
Autor:
Xiu-wu Pan, Da Xu, Wen-jin Chen, Jia-xin Chen, Wei-jie Chen, Jian-qing Ye, Si-shun Gan, Wang Zhou, Xu Song, Lei Shi, Xin-gang Cui
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-16 (2021)
Abstract Background The benefit of targeted therapy for renal cell carcinoma (RCC) is largely crippled by drug resistance. Rapid disease progression and poor prognosis occur in patients with drug resistance. New treatments demand prompt exploration f
Externí odkaz:
https://doaj.org/article/cf0d4c2cd27f4242bee882c5c88df71f
Autor:
Jia-xin Chen, Da Xu, Jian-wei Cao, Li Zuo, Zhi-tao Han, Yi-jun Tian, Chuan-min Chu, Wang Zhou, Xiu-wu Pan, Xin-gang Cui
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Renal cell carcinoma (RCC) is one of the most common malignant tumors originating from the renal parenchymal urinary epithelial system. Tripartite motif 47 (TRIM47) is a member of the TRIM family proteins, which has E3 ligase acti
Externí odkaz:
https://doaj.org/article/78ea8d203c0f477aa76156d8cc552fe7
Autor:
Qi-Wei Yang, Xiu-Wu Pan, Jian-Qing Ye, Chuan-Min Chu, Fa-Jun Qu, Lin Li, Wei Yang, Lei Wang, Si-Shun Gan, Xin-Gang Cui, Qiang Shi
Publikováno v:
Chinese Medical Journal, Vol 134, Iss 2, Pp 228-230 (2021)
Externí odkaz:
https://doaj.org/article/cbca2d0a1e2a410f8cec92ff54fd1a82
Autor:
Chao Wang, Yan Li, Chuan-min Chu, Xiang-min Zhang, Jie Ma, Hai Huang, Yu-ning Wang, Tian-yu Hong, Jing Zhang, Xiu-wu Pan, Jing-cun Zheng, Ning Jiang, Chuan-yi Hu, Xiaojing Ma, Ying-hao Sun, Xin-gang Cui
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 255-264 (2019)
Background: In the clinic, how to stratify renal cell carcinoma (RCC) patients with different risks and to accurately predict their prognostic outcome remains a crucial issue. In this study, we assessed the expression and prognostic value of gankyrin
Externí odkaz:
https://doaj.org/article/a6d47c85d1dd4022a3505470146e2bab