Zobrazeno 1 - 10
of 389
pro vyhledávání: '"Xiu-wu Bian"'
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Tumor‐associatedmacrophages (TAMs) exhibit remarkable heterogeneity in glioblastoma. Spatially resolved single‐cell transcriptomic studies identified a monocyte‐derived TAM subset localized in the peri‐necrotic niche, driven by hypox
Externí odkaz:
https://doaj.org/article/dbff3bb064554fa8a5824884341c9308
Autor:
Kewei Liu, Fanxuan Tian, Xu Chen, Biyin Liu, Shuoran Tian, Yongying Hou, Lei Wang, Mengyi Han, Shiying Peng, Yuting Tan, Yuwei Pan, Zhaole Chu, Jinyang Li, Linrong Che, Dongfeng Chen, Liangzhi Wen, Zhongyi Qin, Xianfeng Li, Junyu Xiang, Xiu‐wu Bian, Qin Liu, Xiaoli Ye, Tao Wang, Bin Wang
Publikováno v:
Advanced Science, Vol 11, Iss 34, Pp n/a-n/a (2024)
Abstract Dysregulation of the transforming growth factor‐β (TGF‐β) signaling pathway regulates cancer stem cells (CSCs) and drug sensitivity, whereas it remains largely unknown how feedback regulatory mechanisms are hijacked to fuel drug‐resi
Externí odkaz:
https://doaj.org/article/448d6be03a8d45519485fb08d94e6a3f
Autor:
Tian‐Hao Liu, Chen‐Yang Zhang, Hang Zhang, Jing Jin, Xue Li, Shi‐Qiang Liang, Yu‐Zheng Xue, Feng‐Lai Yuan, Ya‐Hong Zhou, Xiu‐Wu Bian, Hong Wei
Publikováno v:
iMeta, Vol 3, Iss 3, Pp n/a-n/a (2024)
Abstract The drug response phenotype is determined by a combination of genetic and environmental factors. The high clinical conversion failure rate of gene‐targeted drugs might be attributed to the lack of emphasis on environmental factors and the
Externí odkaz:
https://doaj.org/article/62da27fcbce3441ab799f5abade67645
Autor:
Qiuhong Zhu, Panpan Liang, Hao Meng, Fangzhen Li, Wei Miao, Cuiying Chu, Wei Wang, Dongxue Li, Cong Chen, Yu Shi, Xingjiang Yu, Yifang Ping, Chaoshi Niu, Hai-bo Wu, Aili Zhang, Xiu-wu Bian, Wenchao Zhou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The peptidyl-prolyl cis-trans isomerase Pin1 is a pivotal therapeutic target in cancers, but the regulation of Pin1 protein stability is largely unknown. High Pin1 expression is associated with SUMO1-modified protein hypersumoylation in glio
Externí odkaz:
https://doaj.org/article/68d6219593424984988e9b55888ae088
Autor:
Junyu Xiang, Ni Zhang, Aibei Du, Jinyang Li, Mengyun Luo, Yuzhu Wang, Meng Liu, Luming Yang, Xianfeng Li, Lin Wang, Qin Liu, Dongfeng Chen, Tao Wang, Xiu‐wu Bian, Zhong‐yi Qin, Li Su, Liangzhi Wen, Bin Wang
Publikováno v:
Advanced Science, Vol 10, Iss 35, Pp n/a-n/a (2023)
Abstract Effective treatment for metastasis, a leading cause of cancer‐associated death, is still lacking. To seed on a distal organ, disseminated cancer cells (DCCs) must adapt to the local tissue microenvironment. However, it remains elusive how
Externí odkaz:
https://doaj.org/article/64c023a85571406490f61f9ed3718926
Autor:
Lian Zhang, Yujiao He, Yi Jiang, Qi Wu, Yanchen Liu, Qingqiang Xie, Yuxiu Zou, Jiaqian Wu, Chundong Zhang, Zhongjun Zhou, Xiu-Wu Bian, Guoxiang Jin
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-12 (2023)
Abstract Necroptosis plays a double-edged sword role in necroptotic cancer cell death and tumor immune escape. How cancer orchestrates necroptosis with immune escape and tumor progression remains largely unclear. We found that RIP3, the central activ
Externí odkaz:
https://doaj.org/article/be51e2b2d5484729a54affecb56f772d
Autor:
Pei-Pei Zhang, Zhi-Cheng He, Xiao-Hong Yao, Rui Tang, Jie Ma, Tao Luo, Chuhong Zhu, Tian-Ran Li, Xindong Liu, Dingyu Zhang, Shuyang Zhang, Yi-Fang Ping, Ling Leng, Xiu-Wu Bian
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Severe neurological symptoms are associated with Coronavirus disease 2019 (COVID-19). However, the morphologic features, pathological nature and their potential mechanisms in patient brains have not been revealed despite evidence of neurotro
Externí odkaz:
https://doaj.org/article/69b7bb7621654d2382b8ee1570a265d5
Autor:
Ye Yuan, Li‐Hong Wang, Xian‐Xian Zhao, Jiao Wang, Meng‐Si Zhang, Qing‐Hua Ma, Sen Wei, Ze‐Xuan Yan, Yue Cheng, Xiao‐Qing Chen, Hong‐Bo Zou, Jia Ge, Yan Wang, Xia Zhang, You‐Hong Cui, Tao Luo, Xiu‐Wu Bian
Publikováno v:
Cancer Communications, Vol 42, Iss 9, Pp 868-886 (2022)
Abstract Background Elucidation of the post‐transcriptional modification has led to novel strategies to treat intractable tumors, especially glioblastoma (GBM). The ubiquitin‐proteasome system (UPS) mediates a reversible, stringent and stepwise p
Externí odkaz:
https://doaj.org/article/61ab64593cf34375896dc4f05b09588d
Autor:
You-Li Wu, Feng Wu, Mian-Fu Cao, Yang Lan, Ming-Shan Du, Song-Tao Yu, Yan Wang, Xiao-Chu Yan, Xiu-Wu Bian, Guang-Jie Duan
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Primary pulmonary hyalinizing clear cell carcinoma (HCCC) is a rare salivary gland-type tumor newly recognized in recent years, with approximately 21 cases reported to date in the English literature, which constitutes a challenge in pathology diagnos
Externí odkaz:
https://doaj.org/article/1c0e5a4237a5421aaf75e1e6c4cc7e93
Autor:
Yan-Xia Wang, Haibo Wu, Yong Ren, Shengqing Lv, Chengdong Ji, Dongfang Xiang, Mengsi Zhang, Huimin Lu, Wenjuan Fu, Qing Liu, Zexuan Yan, Qinghua Ma, Jingya Miao, Ruili Cai, Xi Lan, Bin Wu, Wenying Wang, Yinhua Liu, Dai-Zhong Wang, Mianfu Cao, Zhicheng He, Yu Shi, Yifang Ping, Xiaohong Yao, Xia Zhang, Peng Zhang, Ji Ming Wang, Yan Wang, Youhong Cui, Xiu-Wu Bian
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract Medulloblastoma (MB) is one of the most common childhood malignant brain tumors (WHO grade IV), traditionally divided into WNT, SHH, Group 3, and Group 4 subgroups based on the transcription profiles, somatic DNA alterations, and clinical ou
Externí odkaz:
https://doaj.org/article/c19b175391054b93946eadcdcf017196