Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Xiu-jun Wang"'
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 275, Iss , Pp 116239- (2024)
The mechanisms of the exposure to fine particulate matter (PM) as a risk factor for pulmonary injury are not fully understood. The transcription factor, NF-E2-related factor 2 (Nrf2), plays a key role in protection lung against PM insult and cancer c
Externí odkaz:
https://doaj.org/article/936c1c4194cf4a25a5fbd0a9a04777d6
Autor:
Ahmed Hammad, Zhao-Hong Zheng, Akhileshwar Namani, Mohamed Elshaer, Xiu Jun Wang, Xiuwen Tang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background The nuclear phosphatase mitogen-activate protein kinase phosphatase-1 (MKP-1) is a key negative regulator of the innate immune response through the regulation of the biosynthesis of proinflammatory cytokines. In colorectal cancer
Externí odkaz:
https://doaj.org/article/8b1680c8f4f749229317cc398375742b
Autor:
jing ji, Jing Feng, Gang Pan, Ming-Xiao Lv, Jin-Yu Lv, Wen-Wen Liu, Xing-Bei He, Wen-Lian Tang, Qi-Lan Qian, Zhen Zhang, Yu-Xin Xu, Mang-Ru Xie, Dan-Dan Xia, Yu Bao, Xiu-Jun Wang, Jin-Ming Ma, Bin Liu
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 79:353-365
Autor:
Xiuwen Tang, Xiu Jun Wang, John D. Hayes, Lin Luo, Yulong Li, Yangxia Li, Yan Hai, Xiaoyuan Wu, Peng Gao, Miao Geng, Kaihua Liu, Hongyan Wang
PDF file - 499K, Recombinant his-RXRa was unable to interact with GST-hNRF2 mutant fusion protein that lacked residues 209-316 between the Neh5 and Neh6 domains.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023fb76f821861c5a4cb8845663800da
https://doi.org/10.1158/0008-5472.22393946.v1
https://doi.org/10.1158/0008-5472.22393946.v1
Autor:
Xiuwen Tang, Xiu Jun Wang, John D. Hayes, Lin Luo, Yulong Li, Yangxia Li, Yan Hai, Xiaoyuan Wu, Peng Gao, Miao Geng, Kaihua Liu, Hongyan Wang
The transcription factor NRF2 (NFE2L2) is a pivotal activator of genes encoding cytoprotective and detoxifying enzymes that limit the action of cytotoxic therapies in cancer. NRF2 acts by binding antioxidant response elements (ARE) in its target gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9425c923425097ba9811f9cc6ceae5af
https://doi.org/10.1158/0008-5472.c.6503912.v1
https://doi.org/10.1158/0008-5472.c.6503912.v1
Supplementary Figure Legend from Generation of a Stable Antioxidant Response Element–Driven Reporter Gene Cell Line and Its Use to Show Redox-Dependent Activation of Nrf2 by Cancer Chemotherapeutic Agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdb075c1a2fe6475414ae907e4866d2
https://doi.org/10.1158/0008-5472.22366175.v1
https://doi.org/10.1158/0008-5472.22366175.v1
The NF-E2 p45-related factor 2 (Nrf2) regulates cytoprotective genes that contain an antioxidant response element (ARE) in their promoters. To investigate whether anticancer drugs can induce ARE-driven gene expression, we have developed a stable huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09dde76cf882e6a2859f7d92f116af83
https://doi.org/10.1158/0008-5472.c.6495026
https://doi.org/10.1158/0008-5472.c.6495026
Autor:
Xiuwen Tang, Xiu Jun Wang, John D. Hayes, Lin Luo, Yulong Li, Yangxia Li, Yan Hai, Xiaoyuan Wu, Peng Gao, Miao Geng, Kaihua Liu, Hongyan Wang
PDF file - 572K, Cellular co-localization of ectopic GFP and RFP in HEK293T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f5c47008d0af2dd2cdff22b1d0a198
https://doi.org/10.1158/0008-5472.22393943.v1
https://doi.org/10.1158/0008-5472.22393943.v1
Autor:
Xiuwen Tang, Xiu Jun Wang, John D. Hayes, Lin Luo, Yulong Li, Yangxia Li, Yan Hai, Xiaoyuan Wu, Peng Gao, Miao Geng, Kaihua Liu, Hongyan Wang
PDF file - 239K, The interaction of mNrf2 with RXRa in MCF7-RXRa cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b215a246057d31b8cc8c14b86f3fe27
https://doi.org/10.1158/0008-5472.22393931
https://doi.org/10.1158/0008-5472.22393931
Autor:
Xiuwen Tang, Xiu Jun Wang, John D. Hayes, Lin Luo, Yulong Li, Yangxia Li, Yan Hai, Xiaoyuan Wu, Peng Gao, Miao Geng, Kaihua Liu, Hongyan Wang
PDF file - 288K, The binding of NRF2 to the ARE sites in MCF7 and MCF7-RXRo cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4dc36cacc870c8d82f3be536697d26
https://doi.org/10.1158/0008-5472.22393928.v1
https://doi.org/10.1158/0008-5472.22393928.v1