Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Xiu-Yun Zhao"'
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 1, Pp 6-20 (2025)
The endoplasmic reticulum, a key cellular organelle, regulates a wide variety of cellular activities. Endoplasmic reticulum autophagy, one of the quality control systems of the endoplasmic reticulum, plays a pivotal role in maintaining endoplasmic re
Externí odkaz:
https://doaj.org/article/eab50be41323444d9788007240dd08a8
Autor:
Ji-Chuan Liu, Xiu-Yun Zhao, Ming-Lei Wu, Yi-fan Shi, Ze-Ping Huang, Li-Pao Fang, Chao Zhu, Xuan Peng, Zi-Ling Shi, Li-Jun Lan, Wen-Li Ji, Li Luo, Lei Feng, Zeng-Li Zhang, De-en Xu, Shao Li, Zheng-Hong Qin, Yan-Yun Sun, Melitta Schachner, Quan-Hong Ma
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-17 (2024)
Abstract Neurons rely heavily on high mitochondrial metabolism to provide sufficient energy for proper development. However, it remains unclear how neurons maintain high oxidative phosphorylation (OXPHOS) during development. Mitophagy plays a pivotal
Externí odkaz:
https://doaj.org/article/a156d36b40004d2b8152d6ad79d8307b
Autor:
Mei-Hong Lu, Wen-Li Ji, Hong Chen, Yan-Yun Sun, Xiu-Yun Zhao, Fen Wang, Yi Shi, Yan-Ning Hu, Bo-Xiang Liu, Jing-wen Wu, De-En Xu, Jia-Wei Zheng, Chun-Feng Liu, Quan-Hong Ma
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by memory impairments, which has no effective therapy. Stem cell transplantation shows great potential in the therapy of various disease. However, the application of stem cell the
Externí odkaz:
https://doaj.org/article/2e184c9759804955bf4870eae6628a38
Autor:
Xiu-Yun Zhao, Mei-Hong Lu, De-Juan Yuan, De-En Xu, Pei-Pei Yao, Wen-Li Ji, Hong Chen, Wen-Long Liu, Chen-Xiao Yan, Yi-Yuan Xia, Shao Li, Jin Tao, Quan-Hong Ma
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Mitochondria are the double membrane organelles providing most of the energy for cells. In addition, mitochondria also play essential roles in various cellular biological processes such as calcium signaling, apoptosis, ROS generation, cell growth, an
Externí odkaz:
https://doaj.org/article/7d8a18013bfc4381a4478160a94a11f4
Autor:
Zhi‐Hang Huang, Hai Wang, Dong‐Mei Wang, Xiu‐Yun Zhao, Wen‐Wen Liu, Xin Zhong, Dong‐Mei He, Ben‐Rong Mu, Mei‐Hong Lu
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:5779-5793
Alzheimer's disease (AD) is a neurodegenerative disorder with cognitive impairment and abnormal mental behaviour. There is currently no effective cure. The development of early diagnostic markers and the mining of potential therapeutic targets are on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7a5036ae04dcb52448f506b9173996
https://doi.org/10.1111/jcmm.17593
https://doi.org/10.1111/jcmm.17593
Autor:
Xiu-Yun Zhao, Li-Hua Cheng, Ruxiang Xu, Pei-Pei Yao, Luigi Puglielli, De-En Xu, Ji-Bo Chen, Chun-Feng Liu, Ting-Hua Wang, Wen-Li Ji, Zhaotao Wang, Quan-Hong Ma, Rui Huang, Li-Pao Fang, Li-Jun Lan, Mei-Hong Lu
Publikováno v:
Experimental Neurology. 311:67-79
Sphingolipids emerge as essential modulators in the etiology of Alzheimer's disease (AD) with unclear mechanisms. Elevated levels of SM synthase 1 (SMS1), which catalyzes the synthesis of SM from ceramide and phosphatidylcholine, have been observed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c657b12ef7fcef17df0e0c81328e513a
https://doi.org/10.1016/j.expneurol.2018.09.012
https://doi.org/10.1016/j.expneurol.2018.09.012
Autor:
Zhen-Yu Li, Li-Hua Chen, Xiu-Yun Zhao, Hong Chen, Mei-Hong Lu, Yan-Yun Sun, Zhao-Tao Wang, Mei Chen, Li Lu, Wenhui Huang, De-En Xu, Ru-Xiang Xu, Quanhong Ma
Background: Alzheimer’s disease (AD) is a neurodegenerative disorder with limited available drugs for treatment. Enhancing autophagy attenuates AD pathology in various AD model mice. Thus, development of potential drugs enhancing autophagy may brin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47b5d2c76a4f8d7418ed2e873365774d
https://doi.org/10.21203/rs.3.rs-36989/v1
https://doi.org/10.21203/rs.3.rs-36989/v1
Autor:
Ruxiang Xu, Ting-Ting Pan, Ji-Bo Chen, Wen-Li Ji, De-En Xu, Yuchio Yanagawa, Qi-Fa Li, Quan-Hong Ma, Yue Zhang, Shao Li, Mei-Hong Lu, Xiu-Yun Zhao, Fen Wang, Ze-Ping Huang, Chun-Feng Liu, Lu-Lu Xue, Yi-Yuan Xia, Ting-Hua Wang
Publikováno v:
Journal of Alzheimer's disease : JAD. 75(1)
Excitatory (E) and inhibitory (I) balance of neural network activity is essential for normal brain function and of particular importance to memory. Disturbance of E/I balance contributes to various neurological disorders. The appearance of neural hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0ca79613164ef8666d5cec12d6ad49
https://pubmed.ncbi.nlm.nih.gov/32280096
https://pubmed.ncbi.nlm.nih.gov/32280096
Autor:
Mei Chen, Zhao-Tao Wang, Wenhui Huang, Xiu-Yun Zhao, Yan-Yun Sun, Zhen-Yu Li, Li Lu, Quan-Hong Ma, Ruxiang Xu, De-En Xu, Li-Hua Chen, Hong Chen, Mei-Hong Lu, Rui Chen
Publikováno v:
Experimental Neurology. 342:113742
Alzheimer's disease (AD) is a neurodegenerative disorder with limited available drugs for treatment. Enhancing autophagy attenuates AD pathology in various AD model mice. Thus, development of potential drugs which enhance autophagy may bring benefici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a729cd39d8df546b528ecc5ed4fc663
https://doi.org/10.1016/j.expneurol.2021.113742
https://doi.org/10.1016/j.expneurol.2021.113742