Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Xiu-Wen Han"'
Publikováno v:
Life Sciences. 76:2053-2069
Anandamide (arachidonyl-ethanolamide, AEA) is an important endogenous cannabinoid ligand isolated from porcine brain. AEA has a flexible molecular structure with a series of four non-conjugated double bonds, a hydrophobic alkyl chain, and a carboxyam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0196cd10e4aa963ff24e305de25b30d2
https://doi.org/10.1016/j.lfs.2004.08.041
https://doi.org/10.1016/j.lfs.2004.08.041
Publikováno v:
The Journal of Organic Chemistry. 70:1679-1683
Highly enantioselective hydrogenation of exocyclic enamides, (Z)-3-arylidene-4-acyl-3,4-dihydro-2H-benzoxazines, was achieved in up to 98.6% ee by using Rh/(R,R)-Me-Duphos complex as the catalytic system. The absolute configuration of the product was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1506a039af0842d79f0c37c66e651b3
https://doi.org/10.1021/jo048212s
https://doi.org/10.1021/jo048212s
Publikováno v:
Advanced Synthesis & Catalysis. 346:909-912
Chiral ferrocenyloxazoline derived N,P ligands are used in the iridium-catalyzed asymmetric hydrogenation of quinolines, and up to 92% ee was obtained. The role of the planar chirality is also studied.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c576a62e3fc269781fa19aaa7deed252
https://doi.org/10.1002/adsc.200404017
https://doi.org/10.1002/adsc.200404017
Publikováno v:
Journal of Medicinal Chemistry. 42:4021-4027
Aminoalkylindoles (AAIs), although structurally dissimilar from the classical cannabinoids (CCs), are known to be capable of binding to cannabinoid receptors and of evoking cannabimimetic responses. However, their mode of binding remains unknown. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e72af6937dcba37bf0f39ef551bd799
https://doi.org/10.1021/jm980592k
https://doi.org/10.1021/jm980592k
Publikováno v:
Chemical and Pharmaceutical Bulletin. 53:674-676
Two new iridoid glycosides designated as senburiside III (2) and senburiside IV (3), together with one known iridoid glycoside senburiside I (1) and three known secoiridoid glucosides swertiamarin (4), gentiopicroside (5) and sweroside (6), were isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc841e5c1c7ccc90a2cb0753ae3e2131
https://doi.org/10.1248/cpb.53.674
https://doi.org/10.1248/cpb.53.674
Autor:
Shakiru O. Alapafuja, Xiu-Wen Han, Alexandros Makriyannis, Demetris P. Papahatjis, Spyros P. Nikas, Carol A. Paronis, Ioannis Papanastasiou, Anna L. Bowman, Aneetha Halikhedkar, Vidyanand G. Shukla
In pursuit of a more detailed understanding of the structural requirements for the key side chain cannabinoid pharmacophore, we have extended our SAR to cover a variety of conformationally modified side chains within the 9-keto and 9-hydroxyl tricycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adac27b12fe168f2dc873ae8aa3a7cec
https://europepmc.org/articles/PMC3650853/
https://europepmc.org/articles/PMC3650853/
Publikováno v:
ChemInform. 40
t-BuOK was found to be an effective promoting reagent for tandem ring-opening/closing reactions of various N-Ts aziridines and aryl propargyl alcohols to afford dihydroxazine derivatives in moderate to good yields. A plausible reaction mechanism has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0e36e69635c83b7cf458aaf26a22508
https://doi.org/10.1002/chin.200930171
https://doi.org/10.1002/chin.200930171
Publikováno v:
Organic letters. 11(5)
t-BuOK was found to be an effective promoting reagent for tandem ring-opening/closing reactions of various N-Ts aziridines and aryl propargyl alcohols to afford dihydroxazine derivatives in moderate to good yields. A plausible reaction mechanism has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4e023e9ac128879d1929415abb3447
https://pubmed.ncbi.nlm.nih.gov/19191580
https://pubmed.ncbi.nlm.nih.gov/19191580
Publikováno v:
ChemInform. 38
A new catalytic system ([Ru(p-cymene)Cl-2](2)/I-2) has been developed for the hydrogenation of quinoline derivatives with high reactivity. For the 2-methyl-quinoline, the hydrogenation reaction can proceed smoothly at an S/C of 20,000/1 with complete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e06f16c143ff8d377faa6329e1674b
https://doi.org/10.1002/chin.200742142
https://doi.org/10.1002/chin.200742142
Publikováno v:
ChemInform. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4b04ad5e1c5d6515342e8bd509ea76
https://doi.org/10.1002/chin.200632173
https://doi.org/10.1002/chin.200632173