Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Xiu-Rong Dong"'
Publikováno v:
Journal of Developmental Biology, Vol 3, Iss 4, Pp 93-111 (2015)
Proper control of the temporal onset of cellular differentiation is critical for regulating cell lineage decisions and morphogenesis during development. Pbx homeodomain transcription factors have emerged as important regulators of cellular differenti
Externí odkaz:
https://doaj.org/article/d18a7359ece5487a81139895ddb33d10
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61421 (2013)
Hedgehog (Hh) signaling plays fundamental roles in morphogenesis, tissue repair, and human disease. Initiation of Hh signaling is controlled by the interaction of two multipass membrane proteins, patched (Ptc) and smoothened (Smo). Recent studies ide
Externí odkaz:
https://doaj.org/article/024412c336d54677a35007c850171867
Publikováno v:
Circ Res
Transplantation-accelerated arteriosclerosis is one of the major challenges for long-term survival of patients with solid organ transplantation. Although stem/progenitor cells have been implicated to participate in this process, the cells of origin a
Autor:
Jay Shendure, Sarah J. Collins, Kathleen J. Millen, Xiu Rong Dong, Paul Wakenight, Mark W. Majesky, Daryl M. Okamura, Chris M. Brewer, Andrew E. Timms, Aaron McKenna, Branden R. Nelson, William M. Mahoney
Publikováno v:
Developmental Cell. 56:2722-2740.e6
Summary Spiny mice (Acomys cahirinus) are terrestrial mammals that evolved unique scar-free regenerative wound-healing properties. Myofibroblasts (MFs) are the major scar-forming cell type in skin. We found that following traumatic injury to ear pinn
Autor:
Limin Gong, Siddharth K. Prakash, Lawrence Yang Zhu, Regie Lyn P. Santos-Cortez, Shao Qing Kuang, Corey L. Reynolds, Ellen S. Regalado, Eric C. Swindell, Xue Yan Duan, Suzanne M. Leal, Deborah A. Nickerson, Jay Shendure, Guillaume Jondeau, Michael J. Bamshad, Catherine Boileau, Callie S. Kwartler, Milan Jamrich, Andrew M. Peters, Mark W. Majesky, Olga Medina-Martinez, Dianna M. Milewicz, Dongchuan Guo, Xiu-Rong Dong
Publikováno v:
Journal of Clinical Investigation. 126:948-961
The ascending thoracic aorta is designed to withstand biomechanical forces from pulsatile blood. Thoracic aortic aneurysms and acute aortic dissections (TAADs) occur as a result of genetically triggered defects in aortic structure and a dysfunctional
Autor:
Mark W. Majesky, Ko Momotani, Xiu Rong Dong, Li Jin, Mykhaylo V. Artamonov, Avril V. Somlyo, Aaron S. Franke, Ruoya Ho
Publikováno v:
Journal of Biological Chemistry. 290:10353-10367
This study identifies signaling pathways that play key roles in the formation and maintenance of epicardial cells, a source of progenitors for coronary smooth muscle cells (SMCs). After epithelial to mesenchymal transition (EMT), mesenchymal cells in
Publikováno v:
Developmental Biology. 383:307-320
The epicardium and coronary vessels originate from progenitor cells in the proepicardium. Here we show that Tbx18, a T-box family member highly expressed in the proepicardium, controls critical early steps in coronary development. In Tbx18−/− mou
Autor:
Raphael A. Nemenoff, Joanna M. Poczobutt, Henrick Horita, Xiu Rong Dong, Allison C. Ostriker, Jenna N. Regan, Mark W. Majesky, Ashim Bagchi, Sizhao Lu, Mary C.M. Weiser-Evans
Publikováno v:
Circulation research. 120(2)
Rationale: The vascular adventitia is a complex layer of the vessel wall consisting of vasa vasorum microvessels, nerves, fibroblasts, immune cells, and resident progenitor cells. Adventitial progenitors express the stem cell markers, Sca1 and CD34 (
Autor:
Colin T. Maguire, Xiu Rong Dong, Kelly A. Hogan, Victoria L. Bautch, Mark W. Majesky, Jenna Passman, San-Pin Wu
Publikováno v:
Proceedings of the National Academy of Sciences. 105:9349-9354
We characterize a sonic hedgehog (Shh) signaling domain restricted to the adventitial layer of artery wall that supports resident Sca1-positive vascular progenitor cells (AdvSca1). Using patched-1 ( Ptc1 lacZ ) and patched-2 ( Ptc2 lacZ ) reporter mi
Publikováno v:
Journal of Developmental Biology
Volume 3
Issue 4
Pages 93-111
Journal of Developmental Biology, Vol 3, Iss 4, Pp 93-111 (2015)
Journal of developmental biology
Volume 3
Issue 4
Pages 93-111
Journal of Developmental Biology, Vol 3, Iss 4, Pp 93-111 (2015)
Journal of developmental biology
Proper control of the temporal onset of cellular differentiation is critical for regulating cell lineage decisions and morphogenesis during development. Pbx homeodomain transcription factors have emerged as important regulators of cellular differenti