Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Xiu-Juan Yuan"'
Autor:
Sheng-Bin Peng, Sajan Joseph, Ramon V. Tiu, Gregory D. Plowman, Michael J. Rodriguez, Eunice Yuen, Jennie Walgren, Jason Manro, Andrew J. Dropsey, Denis McCann, Xi Rao, Robert D. Van Horn, Meghann Pogue, Xiu-Juan Yuan, Yan Zhai, Bryan Anderson, Wenjuan Wu, Robert S. Flack, Lisa Kindler, Weihua Shen, Matthew Whitesell, Baohui Zhao, Shufen Cai, William T. McMillen, Shripad V. Bhagwat
The ERK pathway is critical in oncogenesis; aberrations in components of this pathway are common in approximately 30% of human cancers. ERK1/2 (ERK) regulates cell proliferation, differentiation, and survival and is the terminal node of the pathway.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b6b83642603b80faa51fcf05c737a2b
https://doi.org/10.1158/1535-7163.c.6538636.v1
https://doi.org/10.1158/1535-7163.c.6538636.v1
Autor:
Sheng-Bin Peng, Sajan Joseph, Ramon V. Tiu, Gregory D. Plowman, Michael J. Rodriguez, Eunice Yuen, Jennie Walgren, Jason Manro, Andrew J. Dropsey, Denis McCann, Xi Rao, Robert D. Van Horn, Meghann Pogue, Xiu-Juan Yuan, Yan Zhai, Bryan Anderson, Wenjuan Wu, Robert S. Flack, Lisa Kindler, Weihua Shen, Matthew Whitesell, Baohui Zhao, Shufen Cai, William T. McMillen, Shripad V. Bhagwat
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d0dc26b8998855020bf945222d1189
https://doi.org/10.1158/1535-7163.22507273.v1
https://doi.org/10.1158/1535-7163.22507273.v1
Autor:
Sheng-Bin Peng, Sajan Joseph, Ramon V. Tiu, Gregory D. Plowman, Michael J. Rodriguez, Eunice Yuen, Jennie Walgren, Jason Manro, Andrew J. Dropsey, Denis McCann, Xi Rao, Robert D. Van Horn, Meghann Pogue, Xiu-Juan Yuan, Yan Zhai, Bryan Anderson, Wenjuan Wu, Robert S. Flack, Lisa Kindler, Weihua Shen, Matthew Whitesell, Baohui Zhao, Shufen Cai, William T. McMillen, Shripad V. Bhagwat
In vivo effect of treatment on body weight loss.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952c561d8520c3c104049374b206e09a
https://doi.org/10.1158/1535-7163.22507276.v1
https://doi.org/10.1158/1535-7163.22507276.v1
Autor:
Sheng-Bin Peng, Sajan Joseph, Ramon V. Tiu, Gregory D. Plowman, Michael J. Rodriguez, Eunice Yuen, Jennie Walgren, Jason Manro, Andrew J. Dropsey, Denis McCann, Xi Rao, Robert D. Van Horn, Meghann Pogue, Xiu-Juan Yuan, Yan Zhai, Bryan Anderson, Wenjuan Wu, Robert S. Flack, Lisa Kindler, Weihua Shen, Matthew Whitesell, Baohui Zhao, Shufen Cai, William T. McMillen, Shripad V. Bhagwat
Summary of antitumor activity of LY3214996 and other MAPK pathway inhibitors in cancer models with dominant MAPK pathway alterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6c4588b08e0998a9a4807fcc3a711c
https://doi.org/10.1158/1535-7163.22507261.v1
https://doi.org/10.1158/1535-7163.22507261.v1
Autor:
Ramon V. Tiu, Michael John Rodriguez, Meghann Pogue, Baohui Zhao, Denis J. McCann, Xiu-Juan Yuan, Wenjuan Wu, William T. McMillen, Shufen Cai, Robert S. Flack, Gregory D. Plowman, Jason Manro, Shripad V. Bhagwat, Matthew Whitesell, Andrew J. Dropsey, Eunice Yuen, Robert D. Van Horn, Lisa Kindler, Sajan Joseph, Jennie L. Walgren, Yan Zhai, Xi Rao, Sheng-Bin Peng, Weihua Shen, Bryan D. Anderson
Publikováno v:
Molecular Cancer Therapeutics. 19:325-336
The ERK pathway is critical in oncogenesis; aberrations in components of this pathway are common in approximately 30% of human cancers. ERK1/2 (ERK) regulates cell proliferation, differentiation, and survival and is the terminal node of the pathway.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0b68b64a3ac95f9cdd0139808ce027
https://doi.org/10.1158/1535-7163.mct-19-0183
https://doi.org/10.1158/1535-7163.mct-19-0183
Autor:
Youyan Zhang, Eliza Vakana, Michele Dowless, Susan Jaken, Louis Stancato, Wayne Blosser, Nicholas Simpson, Lysiane Huber, Sheng-Bin Peng, Susan E. Pratt, Jennifer R. Stephens, Jason Manro, Xiu-Juan Yuan
Publikováno v:
Oncotarget
// Eliza Vakana 1, * , Susan Pratt 1, * , Wayne Blosser 1 , Michele Dowless 1 , Nicholas Simpson 2 , Xiu-Juan Yuan 3 , Susan Jaken 3 , Jason Manro 4 , Jennifer Stephens 1 , Youyan Zhang 1 , Lysiane Huber 1 , Sheng-Bin Peng 1 , Louis F. Stancato 1 1 O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9dee6fe3b13bc87210e961795693e6c
http://europepmc.org/articles/PMC5354729
http://europepmc.org/articles/PMC5354729
Autor:
Deshun Lu1 Lu_Deshun@lilly.com, Xiu-Juan Yuan1 yuanxi@lilly.com, Evans Jr., Robert J.1 evansro@lilly.com, Pappas, Amy T.1 pappasam@lilly.com, He Wang1 hwang@lilly.com, Su, Eric W.1 ewsu@lilly.com, Hamdouchi, Chafiq1 chafiq@lilly.com, Venkataraman, Chandrasekar1 Venkataramanch@lilly.com
Publikováno v:
BMC Immunology. 2005, Vol. 6, p15-10. 10p. 2 Diagrams, 10 Graphs.
Publikováno v:
Advanced Materials Research. :1721-1724
We go deep into the internal structure of the Boolean functions values, and study the relationship of algebraic immunity and algebraic degree of Boolean functions with the Hamming weight with the diffusion included. Then we get some theorems which re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3757f12ce419b8b24c538f8a2683463
https://doi.org/10.4028/www.scientific.net/amr.774-776.1721
https://doi.org/10.4028/www.scientific.net/amr.774-776.1721
Autor:
Marty W. Mayo, Young E. Whang, Lee V. Madrid, Albert S. Baldwin, David R. Jones, Sandy D. Westerheide, Xiu Juan Yuan
Publikováno v:
Journal of Biological Chemistry. 277:11116-11125
PTEN is a lipid phosphatase responsible for down-regulating the phosphoinositide 3-kinase product phosphatidylinositol 3,4,5-triphosphate. Phosphatidylinositol 3,4,5-triphosphate is involved in the activation of the anti-apoptotic effector target, Ak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964cc0726903436611422bfaa02f50ae
https://doi.org/10.1074/jbc.m108670200
https://doi.org/10.1074/jbc.m108670200
Autor:
Young E. Whang, Xiu Juan Yuan
Publikováno v:
Oncogene. 21:319-327
The PTEN tumor suppressor is frequently mutated in human tumors. Loss of PTEN function is associated with constitutive survival signaling through the phosphatidylinositol-3 kinase/Akt pathway. Therefore, we asked if reconstitution of PTEN function wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26896ea7a731d62dbfea19032bc6e95e
https://doi.org/10.1038/sj/onc/1205054
https://doi.org/10.1038/sj/onc/1205054