Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Xiu-Jing Zheng"'
Autor:
Xiang Zhang, Cheng-Hao Xu, Juan Mo, Xiu-Jing Zheng, Yan-Fang Chen, An-Qi Yang, Yi-Heng Zhang, Peng-Yu Wang, Xia Yuan, Xin-Shan Ye
Publikováno v:
ACS Applied Materials & Interfaces. 15:7713-7724
Publikováno v:
Bioconjugate Chemistry. 33:807-820
Dense glycosylation and the trimeric conformation of the human immunodeficiency virus-1 (HIV-1) envelope protein limit the accessibility of some cellular glycan processing enzymes and end up with high-mannose-type
Publikováno v:
RSC Medicinal Chemistry. 12:1239-1243
Globo H is a tumor-associated carbohydrate antigen (TACA), which serves as a valuable target for antitumor vaccine or cancer immunotherapies. However, most TACAs are T-cell-independent, and they cannot induce powerful immune response due to their poo
Publikováno v:
RSC Med Chem
Globo H is a tumor-associated carbohydrate antigen (TACA), which serves as a valuable target for antitumor vaccine or cancer immunotherapies. However, most TACAs are T-cell-independent, and they cannot induce powerful immune response due to their poo
Autor:
Meng-Man Wei, Xin-Shan Ye, Gao-Lan Zhang, De-Cai Xiong, Yu-Feng Ma, Chengcheng Song, Xiu-Jing Zheng
Publikováno v:
Organic Chemistry Frontiers. 5:2179-2188
Vi antigen is the capsular polysaccharide of Salmonella typhi, which can cause typhoid fever. With the increasing threat of antiboitic resistance, vaccination against Salmonella typhi is a preferred way to prevent this disease. Chemical synthesis of
Publikováno v:
Oncotarget
// Chengcheng Song 1, 2 , Xiu-Jing Zheng 1 , Chang-Cheng Liu 1 , Yifa Zhou 2 and Xin-Shan Ye 1 1 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China 2 School of Life Scienc
Autor:
Xin-Shan Ye, Yifa Zhou, Haili Guo, Fan Zhang, Qin Li, Chengcheng Song, Xiu-Jing Zheng, Yafei Cao
Publikováno v:
Glycoconjugate journal. 36(5)
Even though a vaccine that targets tumor-associated carbohydrate antigens on epithelial carcinoma cells presents an attractive therapeutic approach, relatively poor immunogenicity limits its development. In this study, we investigated the immunologic
Publikováno v:
ACS Chemical Biology. 11:1702-1709
Some conserved glycans on the HIV envelope protein are targets of broadly neutralizing antibodies (bnAbs) of HIV. BnAbs provide a precise definition of broadly neutralizing epitopes on the envelope protein of HIV. These epitopes are promising for vac
Publikováno v:
Organic & Biomolecular Chemistry. 14:7226-7237
Glycoprotein MUC1 is an attractive target for anti-tumor vaccine development. However, the weak immunogenicity of MUC1 remains a significant problem. To solve this problem, several STn derivatives with N-acetyl modifications were synthesized and inco
Publikováno v:
Organic & Biomolecular Chemistry. 13:3677-3690
It is well known that tumor cells express some aberrant glycans, termed tumor-associated carbohydrate antigens (TACAs). TACAs are good targets for the development of carbohydrate-based anticancer vaccines. However, one of the major problems is that c