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Reactive Oxygen Species Contributes to Type 2 Diabetic Neuropathic Pain via the Thioredoxin-Interacting Protein-NOD-Like Receptor Protein 3- N -Methyl-D-Aspartic Acid Receptor 2B Pathway

Autor: Jun-Wu Wang, Xiu-Ying Ye, Ning Wei, Shi-Shu Wu, Zhe-Hao Zhang, Guang-Hui Luo, Xu Li, Jun Li, Hong Cao

Publikováno v: Anesthesia and analgesia. 135(4)

The number of patients with diabetic neuropathic pain (DNP) continues to increase, but available treatments are limited. This study aimed to examine the influence of reactive oxygen species (ROS)-thioredoxin-interacting protein (TXNIP)-NOD-like recep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9397a0ca68515325027a29f9636fc8
https://pubmed.ncbi.nlm.nih.gov/35819160

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Kalirin-7 contributes to type 2 diabetic neuropathic pain via the postsynaptic density-95/N-methyl-D-aspartate receptor 2B-dependent N-methyl-D-aspartate receptor 2B phosphorylation in the spinal cord in rats

Autor: Jia-Hui, Lu, Mao-Biao, Zhang, Jun-Wu, Wang, Xiu-Ying, Ye, Jia-Li, Chen, Gai-Li, Jia, Ci-Shan, Xie, Yu-Jing, Shen, Yuan-Xiang, Tao, Jun, Li, Hong, Cao

Publikováno v: Am J Transl Res

Objective: Diabetic neuropathic pain (DNP) is one of the common complications in type 2 Diabetes Mellitus (DM) patients. However, molecular mechanisms in underlying diabetic neuropathic pain are still poorly understood. Kalirin-7, a multifunctional R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc243e0dd076104bc3bc35b8a88b4269
https://pubmed.ncbi.nlm.nih.gov/32913553

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Activation of CaMKII and GluR1 by the PSD-95-GluN2B Coupling-Dependent Phosphorylation of GluN2B in the Spinal Cord in a Rat Model of Type-2 Diabetic Neuropathic Pain

Autor: Ya Bing Zhu, Jun Wu Wang, Yu Jing Shen, Hong Cao, Jia Li Chen, Xiu Ying Ye, Jia Hui Lu, Gai Li Jia, Jun Li, Mao Biao Zhang, Ci Shan Xie, Yuan Xiang Tao

Publikováno v: Journal of neuropathology and experimental neurology. 79(7)

The mechanisms underlying type-2 diabetic neuropathic pain (DNP) are unclear. This study investigates the coupling of postsynaptic density-95 (PSD-95) to N-methyl-D-aspartate receptor subunit 2B (GluN2B), and the subsequent phosphorylation of GluN2B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdae7c91c27d89ffebe919c3031bc070
https://pubmed.ncbi.nlm.nih.gov/32386416

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[Clinical observation on three-combination needling method for treatment of primary trigeminal neuralgia]

Autor: Yi-Yu, Peng, Yi-Sheng, Huang, Su-Lan, Zhang, Xiu-Ying, Ye, Zhen-Rong, Xiong, Jie, Cao

Publikováno v: Zhongguo zhen jiu = Chinese acupuncturemoxibustion. 28(10)

To probe into a better therapy for primary trigeminal neuralgia.Eighty-six cases were randomly divided into an observation group (n = 46) and a control group (n = 40). The observation group were treated with the three-combination needling method, i.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af51c746025101f6fc4c0a0f2618a689
https://pubmed.ncbi.nlm.nih.gov/18972725

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