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Akademický článek

Perirenal fat thickness contributes to the estimated 10-year risk of cardiovascular disease and atherosclerotic cardiovascular disease in type 2 diabetes mellitus

Autor: Wei Wang, Feng Yan Lv, Mei Tu, Xiu Li Guo

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

ObjectivePerirenal adipose tissue (PAT) has emerged as a potential therapeutic target for cardiovascular disease (CVD). However, the relationship between increased perirenal fat thickness (PrFT) and CVD risks in individuals with type 2 diabetes melli

Externí odkaz: https://doaj.org/article/b055a6d7536c4ea4bef6ee394497581f

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Akademický článek

Systemic immune-inflammation index mediates the association between metabolic dysfunction-associated fatty liver disease and sub-clinical carotid atherosclerosis: a mediation analysis

Autor: Wei Wang, Xiu Li Guo, Xiu Ping Qiu, Yun Jie Yu, Mei Tu

Publikováno v: Frontiers in Endocrinology, Vol 15 (2024)

BackgroundLimited research has been conducted to quantitatively assess the impact of systemic inflammation in metabolic dysfunction-associated fatty liver disease (MAFLD) and sub-clinical carotid atherosclerosis (SCAS). The systemic immune-inflammati

Externí odkaz: https://doaj.org/article/26252ec2724d46139e507627ea037d9a

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Akademický článek

Perirenal fat thickness as a superior obesity-related marker of subclinical carotid atherosclerosis in type 2 diabetes mellitus

Autor: Xiu Li Guo, Jian Wen Wang, Mei Tu, Wei Wang

Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)

ObjectiveEmerging evidence highlighted that perirenal adipose tissue might regulate the cardiovascular and metabolism system through several pathways. This study aimed to assess the association between perirenal fat thickness (PrFT) and subclinical c

Externí odkaz: https://doaj.org/article/1c011ee83a8b4709a6b96997ba161968

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Akademický článek

Apolipoprotein A1 is associated with osteocalcin and bone mineral density rather than high-density lipoprotein cholesterol in Chinese postmenopausal women with type 2 diabetes mellitus

Autor: Wei Wang, Zhe Yuan Chen, Fen Yan Lv, Mei Tu, Xiu Li Guo

Publikováno v: Frontiers in Medicine, Vol 10 (2023)

ObjectiveDisturbances in high-density lipoprotein cholesterol (HDL-c) metabolic pathways can affect bone metabolism, which may rely on the particle function of apolipoprotein rather than HDL-c levels. This study aimed to evaluate the correlation of s

Externí odkaz: https://doaj.org/article/f4d768bf3f6f45b59b2e2bc01de3a616

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Akademický článek

Perirenalfat thickness is associated with bone turnover markers and bone mineral density in postmenopausal women with type 2 diabetes mellitus

Autor: Wei Wang, Rong Huang, Ping Tai Tang, Mei Tu, Xiu Li Guo

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

ObjectivesEmerging evidence demonstrated that perirenal fat may modulate bone metabolism through several pathological pathways. This study was aimed to assess the associations between perirenal fat thickness (PrFT) and bone turnover markers (BTMs) an

Externí odkaz: https://doaj.org/article/00dbb993578f4252b4356f398e637f97

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Akademický článek

Monocyte to High-Density lipoprotein and Apolipoprotein A1 Ratios: Novel Indicators for Metabolic Syndrome in Chinese Newly Diagnosed Type 2 Diabetes

Autor: Wei Wang, Zhe Yuan Chen, Xiu Li Guo, Mei Tu

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

ObjectiveIncreasing evidence highlighted that chronic inflammation involved in the development of metabolic syndrome (MetS) and Type 2 diabetes mellitus (T2DM). This prospective study was aimed to assess the association between MetS and novel pro-inf

Externí odkaz: https://doaj.org/article/86e9ea8ae749474481c8556d4f57e462

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Akademický článek

Perirenal Fat Thickness: A Surrogate Marker for Metabolic Syndrome in Chinese Newly Diagnosed Type 2 Diabetes

Autor: Xiu Li Guo, Mei Tu, Yang Chen, Wei Wang

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

ObjectiveIncreasing evidence suggested that perirenal fat thickness (PrFT) was associated with metabolic risk factors. This study aimed to assess the association between PrFT and metabolic syndrome (MetS) in Chinese newly diagnosed type 2 diabetes (T

Externí odkaz: https://doaj.org/article/ad6d385b43d942d289b52c63a3aa00b4

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DSC2 Suppresses the Metastasis of Gastric Cancer through Inhibiting the BRD4/Snail Signaling Pathway and the Transcriptional Activity of β-Catenin

Autor: Chao Sun, Lei Wang, Dan-dan Du, Jian-bo Ji, Xiao-xia Yang, Bing-fang Yu, Peng-fei Shang, Xiu-Li Guo

Publikováno v: Oxidative Medicine and Cellular Longevity. 2022:1-19

Downregulated DSC2 involved in the metastasis of cancers. Unfortunately, its role on the development of gastric cancer (GC) and the potential mechanisms remain unclear. Bioinformatics analysis, Western blot, qRT-PCR, and immunohistochemistry were per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7639803bd4cc762808bdd33404f7e8f8
https://doi.org/10.1155/2022/4813571

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Combination therapy with miR34a and doxorubicin synergistically inhibits Dox-resistant breast cancer progression via down-regulation of Snail through suppressing Notch/NF-κB and RAS/RAF/MEK/ERK signaling pathway

Autor: Jin Qiuyang, Xiu-Li Guo, Jing Liao, Lei Wang, Jianbo Ji, Bingfang Yu, Xiaoxia Yang, Pengfei Shang

Publikováno v: Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2819-2834 (2021)

Resistance to breast cancer (BCa) chemotherapy severely hampers the patient's prognosis. MicroRNAs provide a potential therapeutic prospect for BCa. In this study, the reversal function of microRNA34a (miR34a) on doxorubicin (Dox) resistance of BCa a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d1e2cc77fa6a08f92f69d1dd05e875
http://www.sciencedirect.com/science/article/pii/S221138352100215X

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