Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Xiu‐Xuan Sun"'
Autor:
Huijie Bian, Liang Chen, Zhao-Hui Zheng, Xiu-Xuan Sun, Jie-Jie Geng, Ruo Chen, Ke Wang, Xu Yang, Shi-Rui Chen, Si-Yu Chen, Rong-Hua Xie, Kui Zhang, Jin-Lin Miao, Jun-Feng Jia, Hao Tang, Shuang-Shuang Liu, Hong-Wei Shi, Yong Yang, Xiao-Chun Chen, Vinay Malhotra, Nosheen Nasir, Iffat Khanum, Faisal Mahmood, Saeed Hamid, Claudio Marcel Berdun Stadnik, Kengi Itinose, Caroline Cândida Carvalho de Oliveira, Cesar Dusilek, Lucas Rivabem, Adilson Joaquim Westheimer Cavalcante, Suzara Souto Lopes, Wladmir Faustino Saporito, Fábio José Concilio Fucci, Jesus Abraham Simon-Campos, Ling Wang, Lin-Na Liu, Qing-Yi Wang, Ding Wei, Zheng Zhang, Zhi-Nan Chen, Ping Zhu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Meplazumab, a humanized CD147 antibody, has shown favourable safety and efficacy in our previous clinical studies. In DEFLECT (NCT04586153), 167 patients with severe COVID-19 were enroled and randomized to receive three dosages of meplazumab
Externí odkaz:
https://doaj.org/article/4930312c464b4f5aab592cc1118df724
Autor:
Jiao Wu, Liang Chen, Chuan Qin, Fei Huo, Xue Liang, Xu Yang, Kui Zhang, Peng Lin, Jiangning Liu, Zhuan Feng, Jiansheng Zhou, Zhuo Pei, Yatao Wang, Xiu-Xuan Sun, Ke Wang, Jiejie Geng, Zhaohui Zheng, Xianghui Fu, Man Liu, Qingyi Wang, Zheng Zhang, Huijie Bian, Ping Zhu, Zhi-Nan Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract COVID‐19 patients can develop clinical and histopathological features associated with fibrosis, but the pathogenesis of fibrosis remains poorly understood. CD147 has been identified as a universal receptor for SARS-CoV-2 and its variants,
Externí odkaz:
https://doaj.org/article/f3e46ee400804832b5eb1b08549fe995
Autor:
Hong‐Yong Cui, Wei Wei, Mei‐Rui Qian, Ruo‐Fei Tian, Xin Fu, Hong‐Wei Li, Gang Nan, Ting Yang, Peng Lin, Xi Chen, Yu‐Meng Zhu, Bin Wang, Xiu‐Xuan Sun, Jian‐Hua Dou, Jian‐Li Jiang, Ling Li, Shi‐Jie Wang, Zhi‐Nan Chen
Publikováno v:
Cancer Communications, Vol 42, Iss 8, Pp 750-767 (2022)
Abstract Background The mechanism underlying colorectal cancer (CRC) initiation and progression remains elusive, and overall survival is far from satisfactory. Previous studies have shown that PDGFA‐associated protein 1 (PDAP1) is upregulated in se
Externí odkaz:
https://doaj.org/article/ced8328fe33441678208f1ccfb5e4ab6
Autor:
Hong-Yong Cui, Shi-Jie Wang, Fei Song, Xu Cheng, Gang Nan, Yu Zhao, Mei-Rui Qian, Xi Chen, Jia-Yue Li, Fen-Ling Liu, Yu-Meng Zhu, Ruo-Fei Tian, Bin Wang, Bin Wu, Yang Zhang, Xiu-Xuan Sun, Ting Guo, Xiang-Min Yang, Hai Zhang, Ling Li, Jing Xu, Hui-Jie Bian, Jian-Li Jiang, Zhi-Nan Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-15 (2021)
Abstract Major gaps in understanding the molecular mechanisms of colorectal cancer (CRC) progression and intestinal mucosal repair have hampered therapeutic development for gastrointestinal disorders. Trefoil factor 3 (TFF3) has been reported to be i
Externí odkaz:
https://doaj.org/article/905099627b2b43b695d0164c1941b807
Autor:
Huijie Bian, Zhao-Hui Zheng, Ding Wei, Aidong Wen, Zheng Zhang, Jian-Qi Lian, Wen-Zhen Kang, Chun-Qiu Hao, Jing Wang, Rong-Hua Xie, Ke Dong, Jie-Lai Xia, Jin-Lin Miao, Wen Kang, Guoquan Li, Di Zhang, Mingru Zhang, Xiu-Xuan Sun, Likun Ding, Kui Zhang, Junfeng Jia, Jin Ding, Zhiqin Li, Yanyan Jia, Lin-Na Liu, Zhe Zhang, Zhao-Wei Gao, Hong Du, Na Yao, Qing Wang, Ke Wang, Jie-Jie Geng, Bin Wang, Ting Guo, Ruo Chen, Yu-Meng Zhu, Li-Juan Wang, Qian He, Rui-Rui Yao, Ying Shi, Xiang-Min Yang, Jian-Sheng Zhou, Yi-Nan Ma, Ya-Tao Wang, Xue Liang, Fei Huo, Zhe Wang, Yang Zhang, Xu Yang, Ye Zhang, Lu-Hua Gao, Ling Wang, Xiao-Chun Chen, Hao Tang, Shuang-Shuang Liu, Qing-Yi Wang, Zhi-Nan Chen, Ping Zhu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-11 (2021)
Abstracts Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking CD147 via anti-CD147 antibody could suppress the in vitro SARS-CoV-2 replication. Meplazumab
Externí odkaz:
https://doaj.org/article/5eed9c4f8a264dcb9b830636e8b40c7c
Autor:
Yue Zhai, Liang Chen, Qian Zhao, Zhao-Hui Zheng, Zhi-Nan Chen, Huijie Bian, Xu Yang, Huan-Yu Lu, Peng Lin, Xi Chen, Ruo Chen, Hao-Yang Sun, Lin-Ni Fan, Kun Zhang, Bin Wang, Xiu-Xuan Sun, Zhuan Feng, Yu-Meng Zhu, Jian-Sheng Zhou, Shi-Rui Chen, Tao Zhang, Si-Yu Chen, Jun-Jie Chen, Kui Zhang, Yan Wang, Yang Chang, Rui Zhang, Bei Zhang, Li-Juan Wang, Xiao-Min Li, Qian He, Xiang-Min Yang, Gang Nan, Rong-Hua Xie, Liu Yang, Jing-Hua Yang, Ping Zhu
Publikováno v:
Science. 379
Autoimmune diseases such as ankylosing spondylitis (AS) can be driven by emerging neoantigens that disrupt immune tolerance. Here, we developed a workflow to profile posttranslational modifications involved in neoantigen formation. Using mass spectro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::661892599655adcad762cf5e1595e944
https://doi.org/10.1126/science.abg2482
https://doi.org/10.1126/science.abg2482
Autor:
Zhaohui Zheng, Wen Kang, Mingru Zhang, Ya-Tao Wang, Kui Zhang, Jin Ding, Likun Ding, Yanyan Jia, Ye Zhang, Xiang-Min Yang, Aidong Wen, Ding Wei, Bin Wang, Li-Juan Wang, Lin-Na Liu, Yu-Meng Zhu, Xue Liang, Yi-Nan Ma, Hao Tang, Guoquan Li, Jing Wang, Jie-Lai Xia, Yang Zhang, Hong Du, Zhe Zhang, Xiu-Xuan Sun, Rong-Hua Xie, Jie-Jie Geng, Ke Wang, Ling Wang, Na Yao, Xiao-Chun Chen, Ke Dong, Qing-Yi Wang, Shuang-Shuang Liu, Ping Zhu, Jian-Qi Lian, Junfeng Jia, Qian He, Zhe Wang, Rui-Rui Yao, Zhi-Nan Chen, Ting Guo, Huijie Bian, Chun-Qiu Hao, Jinlin Miao, Wen-Zhen Kang, Di Zhang, Lu-Hua Gao, Xu Yang, Zhao-Wei Gao, Fei Huo, Zheng Zhang, Ruo Chen, Qing Wang, Jian-Sheng Zhou, Ying Shi, Zhiqin Li
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-11 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
sRecent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking CD147 via anti-CD147 antibody could suppress the in vitro SARS-CoV-2 replication. Meplazumab is a hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75687c7363155e1fcbe09c51c370a951
https://doaj.org/article/5eed9c4f8a264dcb9b830636e8b40c7c
https://doaj.org/article/5eed9c4f8a264dcb9b830636e8b40c7c
Autor:
Nai-Shan Zheng, Xiang-Yu Zhao, Ding Wei, Jin-Lin Miao, Ze-Kun Liu, Yu-Le Yong, Ren-Yu Zhang, Yi-Xiao Guo, Lin He, Bin Wang, Xiu-Xuan Sun, Hai-Jiao Yang, Tian-Jiao Zhang, Qian He, Xiao-Min Li, Hai Zhang, Rong Hou, Peng Lin, Ying-Ming Xu, Xiao-Jun Huang, Zhi-Nan Chen, Huijie Bian
Publikováno v:
Cancer letters. 542
T cell acute lymphoblastic leukemia (T-ALL) is invasive and heterogeneous, and existing therapies are sometimes unsuccessful. Chimeric antigen receptor (CAR) T cell therapy is a breakthrough tumor treatment method, particularly for B cell acute lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d7b8d38674a9451a9898e6188003f3
https://pubmed.ncbi.nlm.nih.gov/35659513
https://pubmed.ncbi.nlm.nih.gov/35659513
Autor:
Zhaohui Zheng, Kui Zhang, Ling Li, Ting Guo, Xiaochun Chen, Fengfan Yang, Chuan Qin, Zhang Kun, Yang Zhang, Zhuo Pei, Jiangning Liu, Yu-Meng Zhu, Qingguo Yan, Xue Liang, Jie-Jie Geng, Qing-Yi Wang, Xu Ke, Ming-Yan Shi, Ya-Tao Wang, Jiao Wu, Ying Shi, Yong-Qiang Deng, Peng Lin, Ke Wang, Ding Wei, Peng Du, Liang Chen, Zheng Zhang, Jing Zhang, Yirong Li, Xiu-Xuan Sun, Xu Yang, Hao Tang, Wen Xie, Ping Zhu, Zhe Wang, Zhi-Nan Chen, Guizhen Wu, Youchun Wang, Jian-Li Jiang, Fei Huo, Jun Zhang, Huijie Bian, Ruo Chen, Yufeng Yuan, Hua Zhu, Xianghui Fu, Jinlin Miao
Publikováno v:
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
SARS-CoV-2 mutations contribute to increased viral transmissibility and immune escape, compromising the effectiveness of existing vaccines and neutralizing antibodies. An in-depth investigation on COVID-19 pathogenesis is urgently needed to develop a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3073fcfa61bd25734410465d0da4e5
https://doi.org/10.1038/s41392-021-00760-8
https://doi.org/10.1038/s41392-021-00760-8
Autor:
Yang Zhang, Mei-Rui Qian, Huijie Bian, Zhi-Nan Chen, Xu Cheng, Xiang-Min Yang, Gang Nan, Ruo-Fei Tian, Ting Guo, Yu-Meng Zhu, Yu Zhao, Fen-Ling Liu, Jian-Li Jiang, Ling Li, Jing Xu, Shijie Wang, Xiu-Xuan Sun, Bin Wang, Hong-Yong Cui, Hai Zhang, Jia-Yue Li, Song Fei, Bin Wu, Xi Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-15 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Major gaps in understanding the molecular mechanisms of colorectal cancer (CRC) progression and intestinal mucosal repair have hampered therapeutic development for gastrointestinal disorders. Trefoil factor 3 (TFF3) has been reported to be involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f0df9ce75733e0e32109a48dbfcd2c
https://doi.org/10.1038/s41392-021-00677-2
https://doi.org/10.1038/s41392-021-00677-2