Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Xiting Lian"'
Autor:
LeYuan Gu, WeiHui Shao, Lu Liu, Qing Xu, YuLing Wang, JiaXuan Gu, Yue Yang, ZhuoYue Zhang, YaXuan Wu, Yue Shen, Qian Yu, XiTing Lian, HaiXiang Ma, YuanLi Zhang, HongHai Zhang
Publikováno v:
eLife, Vol 13 (2024)
The advent of midazolam holds profound implications for modern clinical practice. The hypnotic and sedative effects of midazolam afford it broad clinical applicability. However, the specific mechanisms underlying the modulation of altered consciousne
Externí odkaz:
https://doaj.org/article/20ca8e0a75394714835daa95d8d3517f
Autor:
Qing Xu, YuLing Wang, XiTing Lian, Lu Liu, WeiHui Shao, JiaXuan Gu, LeYuan Gu, Qian Yu, YuanLi Zhang, ZhuoYue Zhang, HaiXiang Ma, Yue Shen, HongHai Zhang
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102403- (2023)
Summary: The locus coeruleus (LC) and noradrenergic neurotransmission are involved in the regulation of sudden unexpected death in epilepsy (SUDEP). Here, we present a protocol for modulating the noradrenergic pathway from LC to heart to prevent SUDE
Externí odkaz:
https://doaj.org/article/8c72f32a5717468ea66244f275d37378
Autor:
XiTing Lian, Qing Xu, YuLing Wang, LeYuan Gu, Qian Yu, WeiHui Shao, HaiXiang Ma, Yue Shen, Lu Liu, JiaXuan Gu, HongHai Zhang
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106284- (2023)
Summary: Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among epilepsy patients. However, the underlying mechanism remains elusive. Seizure-induced respiratory arrest (S-IRA) is recognized as a main cause of SUDEP, but the
Externí odkaz:
https://doaj.org/article/560f0abfe75a419e9da826703f82df82
Autor:
YuLing Wang, Qing Xu, Qian Yu, LeYuan Gu, HaiXiang Ma, Yue Shen, XiTing Lian, WeiHui Shao, JiaXuan Gu, Lu Liu, HongHai Zhang
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102129- (2023)
Summary: The dorsal raphe nucleus (DR) and the pre-Bötzinger complex (PBC) may play an important role in regulating seizure-induced respiratory arrest (S-IRA), the main contributor to sudden unexpected death in epilepsy. Here, we describe pharmacolo
Externí odkaz:
https://doaj.org/article/44323863adb249d8b23b64980a5b2a2c
Autor:
HaiXiang Ma, Qian Yu, Yue Shen, XiTing Lian, LeYuan Gu, YuLing Wang, Qing Xu, Han Lu, HaiTing Zhao, Chang Zeng, Kazuki Nagayasu, HongHai Zhang
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105228- (2022)
Summary: Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among patients with epilepsy. However, the underlying mechanism of SUDEP remains elusive. Previous studies showed seizure-induced respiratory arrest (S-IRA) is the mai
Externí odkaz:
https://doaj.org/article/527cf5f575e949d59bc057346885bf51
Autor:
LeYuan Gu, Lu Liu, WeiHui Shao, JiaXuan Gu, Qing Xu, YuLing Wang, Qian Yu, XiTing Lian, HongHai Zhang
Generation of the unconsciousness associated with arousal during the initial stage of anesthesia by midazolam is critical for general anesthesia, however, the exact mechanism remains unknown. Here, firstly, we found that the destruction of noradrener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e2664b4ca5f8877136f1ba0dd5a3684
https://doi.org/10.1101/2023.03.20.533578
https://doi.org/10.1101/2023.03.20.533578
Autor:
Haixiang Ma, Leyuan Gu, Yuling Wang, Qing Xu, Weihui Shao, Qian Yu, Xiting Lian, Lu Liu, Jiaxuan Gu, Na Ji, Yuanli Zhang, Xiaoling Liu, Kazuki Nagayasu, Honghai Zhang
General anesthesia is widely used in various clinical practices due to its ability to cause loss of consciousness. However, the exact mechanism of anesthesia-induced unconsciousness remains unclear. It is generally thought that arousal-related brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69ee5432131b95648ce32dac32cdafaa
https://doi.org/10.21203/rs.3.rs-2665304/v1
https://doi.org/10.21203/rs.3.rs-2665304/v1
Autor:
HaiXiang Ma, LeYuan Gu, YuLing Wang, Qing Xu, Qian Yu, XiTing Lian, WeiHui Shao, Lu Liu, JiaXuan Gu, Yue Shen, HongHai Zhang
In order to explore the mechanism of general anesthesia emergence, based on the common clinical phenomenon-delayed emergence, we explore the role of 5-hydroxytryptamine (5-HT) neurons in the dorsal raphe nucleus in promoting awakening from sevofluran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e26ee2c5762d7904ba8b2c96cfa1882
https://doi.org/10.1101/2022.05.22.492958
https://doi.org/10.1101/2022.05.22.492958
Sudden unexpected death of epilepsy (SUDEP) is the leading cause of of death in patients with epilepsy. Due to the complicated pathogenesis of SUDEP, however, the exact mechanism of SUDEP remains elusive. Currently, although it is recognized that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b9f43a277445701d7e171ff96b09ed4
https://doi.org/10.1101/2022.01.10.475630
https://doi.org/10.1101/2022.01.10.475630
Autor:
Qian Yu, HaiXaing Ma, HaiTing Zhao, Han Lu, Chang Zeng, LeYuan Gu, HongHai Zhang, Kazuki Nagayasu, XiTing Lian, Yue Shen
Sudden unexpected death in epilepsy (SUDEP) is the fatal cause leading to the death of epilepsy patients, especially those with anti-epileptic drug resistance. However, the underlying mechanism of SUDEP remains elusive. Our previous study demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f90ea4e30e3d0ee2dfcbaaffd61f8bd6
https://doi.org/10.1101/2020.12.04.410969
https://doi.org/10.1101/2020.12.04.410969