Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Xitao Xie"'
Autor:
Huiming Zhang, Cheryl Murzello, Yan Sun, Mi-Seong Kim, Xitao Xie, Randall M. Jeter, John C. Zak, Scot E. Dowd, Paul W. Paré
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 23, Iss 8, Pp 1097-1104 (2010)
Choline (Cho) is an essential nutrient for humans as well as the precursor of glycine betaine (GlyBet), an important compatible solute in eukaryotes that protects cells from osmotic stress caused by dehydrating conditions. The key enzyme for plant Ch
Externí odkaz:
https://doaj.org/article/9ef826f428cb4acf8b15a0d3d4f227bc
Autor:
Xiaodong Zhang, Rudolf Zechner, Haiwei Gu, Bradlee L. Heckmann, Xitao Xie, Alicia M. Saarinen, Jun Liu
Publikováno v:
The FASEB Journal. 33:6655-6666
G0/G1 switch gene 2 (G0S2) is a specific inhibitor of adipose triglyceride lipase (ATGL), the rate-limiting enzyme for intracellular lipolysis. Recent studies show that G0S2 plays a critical role in promoting triacylglycerol (TG) accumulation in the
Autor:
Benjamin P. Bowen, Paul R. Langlais, Christian Meyer, Sandeep Sinha, Lawrence J. Mandarino, Meenu Madan, Xitao Xie, Zhengping Yi, Danjun Ma
Publikováno v:
Obesity. 24:1506-1514
Objective To provide a more global view of adipocyte changes in human insulin resistance by proteomics analyses. Methods Baseline biopsies of abdominal subcutaneous adipose tissue were obtained from 23 subjects without diabetes. Euglycemic clamps wer
Autor:
Xiaodong Zhang, Xitao Xie, Heckmann, Bradlee L., Saarinen, Alicia M., Haiwei Gu, Zechner, Rudolf, Jun Liu
Publikováno v:
FASEB Journal; May2019, Vol. 33 Issue 5, p6655-6666, 12p
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 307:E1047-E1056
Fat-specific protein 27 (FSP27) plays a pivotal role in controlling the formation of large lipid droplet and energy metabolism. The cellular levels of FSP27 are tightly regulated through the proteasomal ubiquitin-mediated degradation. However, the up
Autor:
Xiaodong Zhang, Bradlee L. Heckmann, Lawrence J. Mandarino, Xitao Xie, Jun Liu, Alicia M. Saarinen, Paul R. Langlais
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 306:E1449-E1459
Adipose triglyceride lipase (ATGL), the rate-limiting enzyme for triacylglycerol (TG) hydrolysis, has long been known to be a phosphoprotein. However, the potential phosphorylation events that are involved in the regulation of ATGL function remain in
Publikováno v:
Diabetes. 63:934-946
Recent biochemical and cell-based studies identified G0/G1 switch gene 2 (G0S2) as an inhibitor of adipose triglyceride lipase (ATGL), a key mediator of intracellular triacylglycerol (TG) mobilization. Here, we show that upon fasting, G0S2 protein ex
Autor:
Xitao Xie, Xiaodong Zhang, Xingyuan Yang, Alicia M. Saarinen, Jun Liu, Bradlee L. Heckmann, Xin Lu
Publikováno v:
Journal of Biological Chemistry. 289:1905-1916
Biochemical and cell-based studies have identified the G0S2 (G0/G1 switch gene 2) as a selective inhibitor of the key intracellular triacylglycerol hydrolase, adipose triglyceride lipase. To better understand the physiological role of G0S2, we constr
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1831:276-281
The G0/G1 switch gene 2 (G0S2) was originally identified in blood mononuclear cells following induced cell cycle progression. Translation of G0S2 results in a small basic protein of 103 amino acids in size. It was initially believed that G0S2 mediate
Autor:
M Madan, Zhengping Yi, Christian Meyer, Xitao Xie, Sandeep Sinha, Wayne T. Willis, Paul R. Langlais, Benjamin P. Bowen
Publikováno v:
International journal of obesity (2005).
To gain further insight into the role of adipocyte mitochondria in systemic lipid metabolism, inflammation and insulin sensitivity in humans and to provide a better understanding of the mechanisms of action of the peroxisome proliferator-activated re