Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Xiqian Lan"'
Autor:
Jianning Chen, Haiting Xiao, Rui Xue, Vinod Kumar, Rukhsana Aslam, Syed Faizan Mehdi, Huairong Luo, Ashwani Malhotra, Xiqian Lan, Pravin Singhal
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-19 (2023)
Abstract Background Diabetic nephropathy (DN) is a major complication of diabetes mellitus. Clinical reports indicate that smoking is a significant risk factor for chronic kidney disease, and the tobacco epidemic exacerbates kidney damage in patients
Externí odkaz:
https://doaj.org/article/d6b96e99c79d4b48b0f6c9421366e931
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ff7e6424617c4b87872075efbaac09ec
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/844705026c2444fb96f680d2bb786041
Autor:
Cassie Shu Zhu, Wei Wang, Xiaoling Qiang, Weiqiang Chen, Xiqian Lan, Jianhua Li, Haichao Wang
Publikováno v:
Cells, Vol 10, Iss 9, p 2220 (2021)
Sepsis remains a common cause of death in intensive care units, accounting for approximately 20% of total deaths worldwide. Its pathogenesis is partly attributable to dysregulated inflammatory responses to bacterial endotoxins (such as lipopolysaccha
Externí odkaz:
https://doaj.org/article/ed00bd74548a4ca6b1245367b6b4a11c
Autor:
Xiqian Lan, Rivka Lederman, Judith M Eng, Seyedeh Shadafarin Marashi Shoshtari, Moin A Saleem, Ashwani Malhotra, Pravin C Singhal
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167071 (2016)
BackgroundCigarette smoking plays an important role in the progression of chronic kidney disease (CKD). Nicotine, one of the major components of cigarette smoking, has been demonstrated to increase proliferation of renal mesangial cells. In this stud
Externí odkaz:
https://doaj.org/article/41b03aee2cc74313966835174cd12235
Autor:
Xiqian Lan, Partab Rai, Nirupama Chandel, Kang Cheng, Rivka Lederman, Moin A Saleem, Peter W Mathieson, Mohammad Husain, John T Crosson, Kalpna Gupta, Ashwani Malhotra, Pravin C Singhal
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e55748 (2013)
Morphine has been reported to accelerate the progression of chronic kidney disease. However, whether morphine affects slit diaphragm (SD), the major constituent of glomerular filtration barrier, is still unclear. In the present study, we examined the
Externí odkaz:
https://doaj.org/article/58f10f5c3ef1429cb4a2635bcdbe0a2d
Autor:
Zhengang Ma, Chunfeng Li, Guoqing Pan, Zhihong Li, Bing Han, Jinshan Xu, Xiqian Lan, Jie Chen, Donglin Yang, Quanmei Chen, Qi Sang, Xiaocun Ji, Tian Li, Mengxian Long, Zeyang Zhou
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84137 (2013)
Microsporidia have attracted much attention because they infect a variety of species ranging from protists to mammals, including immunocompromised patients with AIDS or cancer. Aside from the study on Nosema ceranae, few works have focused on elucida
Externí odkaz:
https://doaj.org/article/7622d46f69ad4979b1ab27a8e834827c
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50783 (2012)
Proinflammatory cytokine tumor necrosis factor-alpha (TNF-α) is a crucial effector of immune responses in the brain that participates in the pathogenesis of several acute and chronic neurodegenerative disorders. Accumulating evidence has suggested t
Externí odkaz:
https://doaj.org/article/3f3d9e4194e44e919ed69c1f2fec4566
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19439 (2011)
Diminished adult neurogenesis is considered a potential mechanism in the pathogenesis of HIV-1-associated dementia (HAD). In HAD, HIV-1-infected and immune-activated brain mononuclear phagocytes (MP; perivascular macrophages and microglia) drive cent
Externí odkaz:
https://doaj.org/article/57ed4f9f312544bfafb1a88da380b93d
Autor:
Cassie Shu Zhu, Xiaoling Qiang, Weiqiang Chen, Jianhua Li, Xiqian Lan, Huan Yang, Jonathan Gong, Lance Becker, Ping Wang, Kevin J. Tracey, Haichao Wang
Publikováno v:
Science Advances. 9
Antibody-based strategies have been attempted to antagonize early cytokines of sepsis, but not yet been tried to target inducible late-acting mediators. Here, we report that the expression and secretion of procathepsin-L (pCTS-L) was induced by serum