Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Xiongzhi Zeng"'
Publikováno v:
JACS Au, Vol 2, Iss 2, Pp 443-452 (2022)
Externí odkaz:
https://doaj.org/article/0eaf342d651944e696949040e9ef9ae0
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Kv4 potassium channels are responsible for transient outward K+ currents in the cardiac action potential (AP). Previous experiments by our group demonstrated that Jingzhaotoxin-V (JZTX-V) selectively inhibits A-type potassium channels. However, the s
Externí odkaz:
https://doaj.org/article/28ec03ca264e4939a258e1b3d0253d7f
Publikováno v:
Toxins, Vol 6, Iss 8, Pp 2568-2579 (2014)
Intermediate-conductance Ca2+-activated K+ (IK) channels are calcium/calmodulin-regulated voltage-independent K+ channels. Activation of IK currents is important in vessel and respiratory tissues, rendering the channels potential drug targets. A vari
Externí odkaz:
https://doaj.org/article/5a2da890aaa84f2d90860b5fcd7394ef
Publikováno v:
Toxins, Vol 6, Iss 7, Pp 2177-2193 (2014)
Voltage-gated sodium channels (VGSCs; NaV1.1–NaV1.9) have been proven to be critical in controlling the function of excitable cells, and human genetic evidence shows that aberrant function of these channels causes channelopathies, including epileps
Externí odkaz:
https://doaj.org/article/317afe6234df427bb573f244043ee756
Publikováno v:
Toxins, Vol 10, Iss 2, p 64 (2018)
Jingzhaotoxin-34 (JZTX-34) is a selective inhibitor of tetrodotoxin-sensitive (TTX-S) sodium channels. In this study, we found that JZTX-34 selectively acted on Nav1.7 with little effect on other sodium channel subtypes including Nav1.5. If the DIIS3
Externí odkaz:
https://doaj.org/article/96fedad530e54ebfbd916caa68b26f2e
Autor:
Yiya Zhang, Yong Huang, Quanze He, Jinyan Liu, Ji Luo, Li Zhu, Shanshan Lu, Pengfei Huang, Xinyi Chen, Xiongzhi Zeng, Songping Liang
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100682 (2014)
Spider venom comprises a mixture of compounds with diverse biological activities, which are used to capture prey and defend against predators. The peptide components bind a broad range of cellular targets with high affinity and selectivity, and appea
Externí odkaz:
https://doaj.org/article/7ad26c6b31bb464fa05ec0d962014da0
Publikováno v:
International Journal of Peptide Research & Therapeutics; May2024, Vol. 30 Issue 3, p1-9, 9p
Publikováno v:
Chinese Journal of Chemical Physics. 35:1-15
Nanosystems play an important role in many applications. Due to their complexity, it is challenging to accurately characterize their structure and properties. An important means to reach such a goal is computational simulation, which is grounded on a
Autor:
Luzhao Sun, Buhang Chen, Wendong Wang, Yanglizhi Li, Xiongzhi Zeng, Haiyang Liu, Yu Liang, Zhenyong Zhao, Ali Cai, Rui Zhang, Yeshu Zhu, Yuechen Wang, Yuqing Song, Qingjie Ding, Xuan Gao, Hailin Peng, Zhenyu Li, Li Lin, Zhongfan Liu
Publikováno v:
ACS Nano. 16:285-294
The epitaxial growth of single-crystal thin films relies on the availability of a single-crystal substrate and a strong interaction between epilayer and substrate. Previous studies have reported the roles of the substrate (
Publikováno v:
The journal of physical chemistry letters. 13(28)
The potential energy surface (PES) is crucial for interpreting a variety of chemical reaction processes. However, predicting accurate PESs with high-level electronic structure methods is a challenging task due to the high computational cost. As an ap