Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Xionglin Fan"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Coronavirus disease 2019 (COVID-19) pandemic is a serious threat to global public health and social and economic development. Various vaccine platforms have been developed rapidly and unprecedentedly, and at least 16 vaccines receive emergency use au
Externí odkaz:
https://doaj.org/article/b58f191aff914f5eb4c8f384750a530c
Autor:
Yang Li, Zhaowei Xu, Qing Lei, Dan-yun Lai, Hongyan Hou, He-wei Jiang, Yun-xiao Zheng, Xue-ning Wang, Jiaoxiang Wu, Ming-liang Ma, Bo Zhang, Hong Chen, Caizheng Yu, Jun-biao Xue, Hai-nan Zhang, Huan Qi, Shu-juan Guo, Yandi Zhang, Xiaosong Lin, Zongjie Yao, Huiming Sheng, Ziyong Sun, Feng Wang, Xionglin Fan, Sheng-ce Tao
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109391- (2021)
Summary: The immunogenicity of the SARS-CoV-2 proteome is largely unknown, especially for non-structural proteins and accessory proteins. In this study, we collect 2,360 COVID-19 sera and 601 control sera. We analyze these sera on a protein microarra
Externí odkaz:
https://doaj.org/article/cdba430fbaa340038ec8e9d543016c7d
Autor:
Yang Li, Ming-liang Ma, Qing Lei, Feng Wang, Wei Hong, Dan-yun Lai, Hongyan Hou, Zhao-wei Xu, Bo Zhang, Hong Chen, Caizheng Yu, Jun-biao Xue, Yun-xiao Zheng, Xue-ning Wang, He-wei Jiang, Hai-nan Zhang, Huan Qi, Shu-juan Guo, Yandi Zhang, Xiaosong Lin, Zongjie Yao, Jiaoxiang Wu, Huiming Sheng, Yanan Zhang, Hongping Wei, Ziyong Sun, Xionglin Fan, Sheng-ce Tao
Publikováno v:
Cell Reports, Vol 34, Iss 13, Pp 108915- (2021)
Summary: To fully decipher the immunogenicity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike protein, it is essential to assess which part is highly immunogenic in a systematic way. We generate a linear epitope landscape of
Externí odkaz:
https://doaj.org/article/47c8b794ca2844f29aa78af66e730aea
Autor:
Qing Lei, Hongyan Hou, Caizheng Yu, Yandi Zhang, Jo-Lewis Banga Ndzouboukou, Xiaosong Lin, Zongjie Yao, Hui Fu, Ziyong Sun, Feng Wang, Xionglin Fan
Publikováno v:
Journal of Immunology Research, Vol 2021 (2021)
Background. Neutralizing antibody (nAb) response is generated following infection or immunization and plays an important role in the protection against a broad of viral infections. The role of nAb during clinical progression of coronavirus disease 20
Externí odkaz:
https://doaj.org/article/a627ee8b4fcc46bd9dc201dcc6987935
Autor:
Ling Hao, Yaqi Wu, Yandi Zhang, Zijie Zhou, Qing Lei, Nadeem Ullah, Jo-Lewis Banga Ndzouboukou, Xiaosong Lin, Xionglin Fan
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Bacillus Calmette-Guerin (BCG) is the only licensed vaccine to prevent children from tuberculosis (TB), whereas it cannot provide effective protection for adults. Our previous work showed a novel vaccine candidate, liposomal adjuvant DMT emulsified w
Externí odkaz:
https://doaj.org/article/5198d149f5134443ba4a01099752ca36
Autor:
Nadeem Ullah, Ling Hao, Yaqi Wu, Yandi Zhang, Qing Lei, Jo-Lewis Banga Ndzouboukou, Xiaosong Lin, Xionglin Fan
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Tuberculosis (TB) remains a major and global problem of public health. An effective TB subunit vaccine is urgently needed. Proper selection of the delivery system for the vaccine is crucial for inducing an appropriate immune response tailored to cont
Externí odkaz:
https://doaj.org/article/ef9c98debc6f455aa092e21b03acd0e7
Autor:
Jilei Ma, Xindong Teng, Xiaochun Wang, Xionglin Fan, Yaqi Wu, Maopeng Tian, Zijie Zhou, Longmeng Li
Publikováno v:
EBioMedicine, Vol 22, Iss C, Pp 143-154 (2017)
Adult tuberculosis (TB) is the main cause of TB epidemic and death. The infection results mainly by endogenous reactivation of latent TB infection and secondarily transmitted by exogenous infection. There is no vaccine for adult TB. To this end, we f
Externí odkaz:
https://doaj.org/article/2084659bf1c042f0b421730abe427c99
Autor:
Nadeem Ullah, Ling Hao, Jo-Lewis Banga Ndzouboukou, Shiyun Chen, Yaqi Wu, Longmeng Li, Eman Borham Mohamed, Yangbo Hu, Xionglin Fan
Publikováno v:
Pathogens, Vol 10, Iss 5, p 607 (2021)
Rifampicin (RIF) is one of the most important first-line anti-tuberculosis (TB) drugs, and more than 90% of RIF-resistant (RR) Mycobacterium tuberculosis clinical isolates belong to multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB. I
Externí odkaz:
https://doaj.org/article/3a9d0d9e76454586aff054e5a6ad998f
Autor:
Yaqi Wu, Ming Cai, Jilei Ma, Xindong Teng, Maopeng Tian, Eman Borham Mohamed Borham Bassuoney, Xionglin Fan
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Adults are the leading population affected by tuberculosis (TB) epidemic and death. Developing an effective vaccine against adult TB is urgently needed. Mycobacterium bovis Bacillus Calmette-Guerin (BCG) prime-heterologous boost strategy has been exp
Externí odkaz:
https://doaj.org/article/8d025be2abe748f383f2dd6e63588be0
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Despite the vaccine Mycobacterium bovis Bacillus Calmette–Guérin is used worldwide, tuberculosis (TB) remains the first killer among infectious diseases. An effective vaccine is urgently required. DNA vaccine has shown prophylactic as well as ther
Externí odkaz:
https://doaj.org/article/a61737d2f4004c30978bfc96fca82961