Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Xiongjie Shi"'
Autor:
Xuping Yang, Qinhui Liu, Yanping Li, Qin Tang, Tong Wu, Lei Chen, Shiyun Pu, Yingnan Zhao, Guorong Zhang, Cuiyuan Huang, Jinhang Zhang, Zijing Zhang, Ya Huang, Min Zou, Xiongjie Shi, Wei Jiang, Rui Wang, Jinhan He
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 484-494 (2020)
The diabetes medication canagliflozin (Cana) is a sodium glucose cotransporter 2 (SGLT2) inhibitor acting by increasing urinary glucose excretion and thus reducing hyperglycaemia. Cana treatment also reduces body weight. However, it remains unclear w
Externí odkaz:
https://doaj.org/article/6af5c4ed9b494dcbaec0f4ee17d251b8
Autor:
Biran Zhu, Lei Lei, Yumiao Sun, Xiongjie Shi, Kaiyu Fu, Jianghuan Hua, Christopher J. Martyniuk, Jian Han, Lihua Yang, Bingsheng Zhou
Publikováno v:
Environmental sciencetechnology. 56(16)
In the current study, adult male zebrafish fed a normal diet (ND) or high-fat diet (HFD) were exposed to niclosamide (NIC) at environmentally relevant concentrations to reveal the accumulation and distribution in different tissues and evaluate the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d208f453642067d36502c4b2e4d964
https://pubmed.ncbi.nlm.nih.gov/35901075
https://pubmed.ncbi.nlm.nih.gov/35901075
Autor:
Jie Luo, Wei Qi, Ao Hu, Ju-Qiong Wang, Yi Ding, Ming Sun, Xiongjie Shi, Bao-Liang Song, Xiao-Yi Lu, Wei Jiang, Xiaolu Zhao
Publikováno v:
Nature. 588:479-484
Cholesterol is an essential lipid and its synthesis is nutritionally and energetically costly1,2. In mammals, cholesterol biosynthesis increases after feeding and is inhibited under fasting conditions3. However, the regulatory mechanisms of cholester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7c311faab1a47077561cc443321c45
https://doi.org/10.1038/s41586-020-2928-y
https://doi.org/10.1038/s41586-020-2928-y
Autor:
Bao-Liang Song, Le-Wei Dong, Xiongjie Shi, Xiaolu Zhao, Yanni Xiong, Ju-Qiong Wang, Jian Xiao, Liu-Ting Yang, Zi-Mu Zhou, Jie Luo
Publikováno v:
Protein & Cell, Vol 12, Iss 4, Pp 279-296 (2020)
Protein & Cell
Protein & Cell
Sterol-regulatory element binding proteins (SREBPs) are the key transcriptional regulators of lipid metabolism. The activation of SREBP requires translocation of the SREBP precursor from the endoplasmic reticulum to the Golgi, where it is sequentiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559f59183e997700b834489f11fd6547
https://doi.org/10.1007/s13238-020-00753-3
https://doi.org/10.1007/s13238-020-00753-3
Publikováno v:
Environmental Science & Technology. 54:355-363
Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate (TBPH) is a ubiquitous environmental contaminant, but its toxicity is not fully understood. Accordingly, we investigated the effects of TBPH and its metabolite, mono-(2-ethyhexyl)tetrabromophthalate (TBME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0984163595d05ac4b378d4d2e362fb52
https://doi.org/10.1021/acs.est.9b05796
https://doi.org/10.1021/acs.est.9b05796
Autor:
Ming Sun, Lu Yi Jiang, Bao-Liang Song, Liang Chen, Xian Xiu Fang, Guanghou Shui, Xiongjie Shi, Jie Luo, Sin Man Lam, Mei Yan Ma, Xue Tong Zhao
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 10, Pp 1765-1775 (2019)
Sterol-regulated HMG-CoA reductase (HMGCR) degradation and SREBP-2 cleavage are two major feedback regulatory mechanisms governing cholesterol biosynthesis. Reportedly, lanosterol selectively stimulates HMGCR degradation, and cholesterol is a specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590aa33dbe350de4305b447a609d52db
https://doi.org/10.1194/jlr.ra119000201
https://doi.org/10.1194/jlr.ra119000201
Autor:
Chang Xie, Ya-Cheng Liao, Bo-Liang Li, Zi-Mu Zhou, Bao-Liang Song, Hong-Hua Miao, Xiongjie Shi, Jie Luo, Jian Xiao, Bei-Bei Chu, Luyi Jiang, Mei-Xin Li, Ting Xiao, Ao Hu, Zekai Kong
Publikováno v:
Science China Life Sciences. 62:1117-1135
Most mammalian cells take up cholesterol from low-density lipoproteins (LDLs) via receptor-mediated endocytosis. After reaching lysosomes, LDL-derived cholesterol continues to transport to downstream organelles including the ER for specific structura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c89fe77013c4deec4e6ca11153a01d9e
https://doi.org/10.1007/s11427-019-9569-9
https://doi.org/10.1007/s11427-019-9569-9
Autor:
Chang Xie, Ting Xiao, Jiqiu Wang, Jie Hong, Wei Qi, Jian Wei, Yun-Feng Li, Xiongjie Shi, Xue-Min Gong, Bo-Liang Li, Ju-Qiong Wang, Guang Ning, Bao-Liang Song, Jie Luo
Publikováno v:
Nature Metabolism. 1:570-583
Metabolism in mammals is regulated by complex interplay among different organs. Fatty acid synthesis is increased in white adipose tissue (WAT) when it is inhibited in the liver. Here we identify glycoprotein non-metastatic melanoma protein B (Gpnmb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b7c049a134da5e1d598768abee382a
https://doi.org/10.1038/s42255-019-0065-4
https://doi.org/10.1038/s42255-019-0065-4
Publikováno v:
Environmental Pollution. 247:293-301
The growing production and extensive use of organophosphate flame retardants (OPFRs) have led to an increase in their environmental distribution and human exposure. Developmental toxicity is a major concern of OPFRs' adverse health effects. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f06c64039ae4b925c336f543c24957
https://doi.org/10.1016/j.envpol.2018.12.066
https://doi.org/10.1016/j.envpol.2018.12.066
Autor:
Wen-Wei Qiu, Wang Jie, Fan Yang, Jie Luo, Bao-Liang Song, Wei Qi, Hui Li, Shi-You Jiang, Jie Tang, Jin-Kai Wang, Xiongjie Shi, Jing-Jie Tang, Bing Liu, Hai-Wei Cui
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
Statins are inhibitors of HMG-CoA reductase, the rate-limiting enzyme of cholesterol biosynthesis, and have been clinically used to treat cardiovascular disease. However, a paradoxical increase of reductase protein following statin treatment may atte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda3908f58e97e3451eb6bd260dba8db
http://link.springer.com/article/10.1038/s41467-018-07590-3
http://link.springer.com/article/10.1038/s41467-018-07590-3