Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Xionghao Lin"'
Autor:
Balamurugan Packialakshmi, Emily Limerick, Hans C. Ackerman, Xionghao Lin, Sergei Nekhai, James D. Oliver, Ian J. Stewart, Mark A. Knepper, Courtney Fitzhugh, Xiaoming Zhou
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Sickle cell nephropathy (SCN) is a leading cause of morbidity and mortality in sickle cell disease (SCD). Early intervention is crucial for mitigating its effects. However, current diagnostic methods rely on generic tests and may not detect SCN until
Externí odkaz:
https://doaj.org/article/7a05457372a249c682dc078f533230cd
Autor:
Namita Kumari, Asrar Ahmad, Clemilson Berto-Junior, Andrey Ivanov, Fayuan Wen, Xionghao Lin, Sharmin Diaz, Iheanyi Okpala, James G. Taylor, VI, Marina Jerebtsova, Sergei Nekhai
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108813- (2024)
Summary: Sickle cell disease (SCD) is characterized by hemolysis, vaso-occlusion, and ischemia. HIV-1 infection was previously shown to be suppressed in SCD PBMCs. Here, we report that HIV-1 suppression is attributed to the increased expression of ir
Externí odkaz:
https://doaj.org/article/4bbe06d506ad444d967a38da2597546b
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/58ff4637b4584a2c82169daaf1324efd
Autor:
Carmen Stecher, Sanja Marinkov, Lucia Mayr-Harting, Ana Katic, Marie-Theres Kastner, Franz J. J. Rieder-Rommer, Xionghao Lin, Sergei Nekhai, Christoph Steininger
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Human cytomegalovirus (HCMV) carries the human protein phosphatase 1 (PP1) and other human proteins important for protein translation in its tegument layer for a rapid supply upon infection. However, the biological relevance behind PP1 incorporation
Externí odkaz:
https://doaj.org/article/42440a3da85b49728b006a1bfe90dc33
Autor:
Andrey Ivanov, Xionghao Lin, Tatiana Ammosova, Andrey V. Ilatovskiy, Namita Kumari, Hatajai Lassiter, Nowah Afangbedji, Xiaomei Niu, Michael G. Petukhov, Sergei Nekhai
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-23 (2018)
Abstract Background HIV-1 transcription activator protein Tat is phosphorylated in vitro by CDK2 and DNA-PK on Ser-16 residue and by PKR on Tat Ser-46 residue. Here we analyzed Tat phosphorylation in cultured cells and its functionality. Results Mass
Externí odkaz:
https://doaj.org/article/5d0f09d884364e67bf1122b20246c298
Autor:
Awadh Alanazi, Andrey Ivanov, Namita Kumari, Xionghao Lin, Songping Wang, Dmytro Kovalskyy, Sergei Nekhai
Publikováno v:
Viruses, Vol 13, Iss 10, p 2004 (2021)
The HIV-1 Tat protein interacts with TAR RNA and recruits CDK9/cyclin T1 and other host factors to induce HIV-1 transcription. Thus, Tat–TAR RNA interaction, which is unique for HIV-1, represents an attractive target for anti-HIV-1 therapeutics. To
Externí odkaz:
https://doaj.org/article/8306fee3070542aab3c600b29a022a81
Autor:
Namita Kumari, Tatiana Ammosova, Sharmin Diaz, Xionghao Lin, Xiaomei Niu, Andrey Ivanov, Marina Jerebtsova, Subhash Dhawan, Patricia Oneal, Sergei Nekhai
Publikováno v:
Blood Advances, Vol 1, Iss 3, Pp 170-183 (2016)
Abstract: The low incidence of HIV-1 infection in patients with sickle cell disease (SCD) and inhibition of HIV-1 replication in vitro under the conditions of low intracellular iron or heme treatment suggests a potential restriction of HIV-1 infectio
Externí odkaz:
https://doaj.org/article/2e2cc677196b44009c2cc815a6598f35
Autor:
Xionghao Lin, Tatiana Ammosova, Meng S. Choy, Colette A. Pietzsch, Andrey Ivanov, Asrar Ahmad, Yasemin Saygideğer, Namita Kumari, Dmytro Kovalskyy, Aykut Üren, Wolfgang Peti, Alexander Bukreyev, Sergei Nekhai
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Ebola virus (EBOV) is a non-segmented negative-sense RNA virus that causes a severe human disease. The ongoing EBOV outbreak in the Eastern part of Democratic Republic of the Congo has resulted to date in over 2500 confirmed cases including over 1500
Externí odkaz:
https://doaj.org/article/cef38a91be7c4905b107b9da78868f86
Autor:
Packialakshmi, Balamurugan, Limerick, Emily, Ackerman, Hans C., Xionghao Lin, Nekhai, Sergei, Oliver III, James D., Stewart, Ian J., Knepper, Mark A., Fitzhugh, Courtney, Xiaoming Zhou
Publikováno v:
Frontiers in Physiology; 2024, p1-14, 14p
Autor:
Xionghao Lin, Sergei Nekhai, Dmitri Sviridov, Michael Bukrinsky, Adam R. Ward, Tatiana Pushkarsky, Andrey Ivanov
Publikováno v:
Molecular Neurobiology. 59:1088-1097
HIV-associated neurocognitive disorders (HAND) is a term used to describe a variety of neurological impairments observed in HIV-infected individuals. The pathogenic mechanisms of HAND and of its connection to HIV infection remain unknown, but one of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49522be8434dbc6ae5fc66515f242979
https://doi.org/10.1007/s12035-021-02608-2
https://doi.org/10.1007/s12035-021-02608-2