Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Xiong‐Wen Zhang"'
Corylifol A ameliorates muscle atrophy by inhibiting TAOK1/p38‐MAPK/FoxO3 pathway in cancer cachexia
Autor:
Ruiqin Zhang, Qiang Shen, Yueping Wang, Xue Deng, Jialing Fan, Xiaofan Gu, Meng Fan, Kun Wei, Chun‐Ru Cheng, Wei‐Dong Zhang, Xiong‐wen Zhang, Xuan Liu
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 5, Pp 2098-2113 (2023)
Abstract Background Corylifol A (CYA) is one of the main active components of Psoralea corylifolia L. CYA had been reported to have ameliorating effects on dexamethasone‐induced atrophy of C2C12 mouse skeletal myotubes, but its effects on cancer ca
Externí odkaz:
https://doaj.org/article/01758432d18e47698922a96cd0b6ce6e
Autor:
Qiao-Yu Fang, Yue-Ping Wang, Rui-Qin Zhang, Meng Fan, Li-Xing Feng, Xiao-Dong Guo, Chun-Ru Cheng, Xiong-Wen Zhang, Xuan Liu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Introduction: Carnosol exhibited ameliorating effects on muscle atrophy of mice developed cancer cachexia in our previous research.Method: Here, the ameliorating effects of carnosol on the C2C12 myotube atrophy result from simulated cancer cachexia i
Externí odkaz:
https://doaj.org/article/9a36eac94e424db5a4b09e00b3937853
Autor:
Yu-Shui Ma, Kai-Jian Chu, Chang-Chun Ling, Ting-Miao Wu, Xu-Chao Zhu, Ji-Bin Liu, Fei Yu, Zhi-Zhen Li, Jing-Han Wang, Qing-Xiang Gao, Bin Yi, Hui-Min Wang, Li-Peng Gu, Liu Li, Lin-Lin Tian, Yi Shi, Xiao-Qing Jiang, Da Fu, Xiong-Wen Zhang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 324- (2022)
Externí odkaz:
https://doaj.org/article/7ad2da247b944c84b179fbeae5fd10cd
Autor:
Yu-Shui Ma, Kai-Jian Chu, Chang-Chun Ling, Ting-Miao Wu, Xu-Chao Zhu, Ji-Bin Liu, Fei Yu, Zhi-Zhen Li, Jing-Han Wang, Qing-Xiang Gao, Bin Yi, Hui-Min Wang, Li-Peng Gu, Liu Li, Lin-Lin Tian, Yi Shi, Xiao-Qing Jiang, Da Fu, Xiong-Wen Zhang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 229-241 (2020)
Numerous studies have suggested that dysregulated long noncoding RNAs (lncRNAs) contributed to the development and progression of many cancers. lncRNA OIP5 antisense RNA 1 (OIP5-AS1) has been reported to be increased in several cancers. However, the
Externí odkaz:
https://doaj.org/article/18068193cbee457d9a7e1006084c5708
Autor:
Chao Zhang, Na Yang, Chun-Hao Yang, Hua-Sheng Ding, Cheng Luo, Yu Zhang, Mao-Jiang Wu, Xiong-Wen Zhang, Xu Shen, Hua-Liang Jiang, Ling-Hua Meng, Jian Ding
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4881 (2009)
BACKGROUND: Deregulation of the phosphatidylinositol 3-kinases (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway plays a central role in tumor formation and progression, providing validated targets for cancer therapy. S9, a hybrid of alpha-meth
Externí odkaz:
https://doaj.org/article/f10535cd57594174ba42b5099b64f719
Autor:
Bai, Cui-Bing, Qiao, Rui, Liao, Jia-Xin, Xiong, Wen-Zhang, Zhang, Jie, Chen, Shui-Sheng, Yang, Song
Publikováno v:
In Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 5 September 2018 202:252-259
Autor:
Ji‐Xia Kuang, Qiang Shen, Rui‐Qin Zhang, Qiao‐Yu Fang, Xue Deng, Meng Fan, Chun‐Ru Cheng, Xiong‐Wen Zhang, Xuan Liu
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 131:500-513
Cancer-derived exosomes are involved in the development of cancer cachexia. Carnosol, which exhibited ameliorating effects on cancer cachexia of C26 tumour-bearing mice in our previous study, alleviated atrophy of C2C12 myotubes induced by exosomes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a5461d46fd7ac2fe9bb3173c6ec97f
https://doi.org/10.1111/bcpt.13795
https://doi.org/10.1111/bcpt.13795
Autor:
Qiao, Rui1,2 qiaorui@mail.ipc.ac.cn, Xiong, Wen-Zhang1, Bai, Cui-Bing1,2 baicuibing@126.com, Liao, Jia-Xin1, Zhang, Lin1,2
Publikováno v:
Supramolecular Chemistry. Nov2018, Vol. 30 Issue 11, p911-917. 7p.
Akademický článek
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Autor:
Hong-yu Li, Yan Nan Kong, Meng Li Zhu, Jian Bei Xi, Feng Jie Guan, Yanfen Fang, Mingliang Ma, Brendan Frett, Xiong Wen Zhang, Wenhao Hu, Yun Zhao, Tong Zhu
Publikováno v:
European journal of medicinal chemistry. 126
We present herein the discovery and development of novel and potent Nek2 inhibitors with distinctive in vitro and in vivo antitumor activity based on an imidazo[1,2-a]pyridine scaffold. Our studies identified a nonlinear SAR for activity against both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b076e4a73e7c54ff0d9d231c92fb25a
https://pubmed.ncbi.nlm.nih.gov/28039836
https://pubmed.ncbi.nlm.nih.gov/28039836