Výsledky vyhledávání - "Xiong‐Ke Hu"

Akademický článek

Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)

This study uncovers the role of extracellular vesicles from bone matrix as a messenger in the development of osteoporosis and vascular calcification (calcification paradox) during skeletal aging and menopause by transferring miR-483-5p and miR-2861.

Externí odkaz: https://doaj.org/article/ab6085afb96c4c6ca3fad64ef9bffdb0

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Akademický článek

Neuronal Induction of Bone‐Fat Imbalance through Osteocyte Neuropeptide Y

Publikováno v: Advanced Science, Vol 8, Iss 24, Pp n/a-n/a (2021)

Abstract A differentiation switch of bone marrow mesenchymal stem/stromal cells (BMSCs) from osteoblasts to adipocytes contributes to age‐ and menopause‐associated bone loss and marrow adiposity. Here it is found that osteocytes, the most abundan

Externí odkaz: https://doaj.org/article/c95444b404b64534abd3b7ebb0ee29c2

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Akademický článek

Extracellular Vesicles from Child Gut Microbiota Enter into Bone to Preserve Bone Mass and Strength

Publikováno v: Advanced Science, Vol 8, Iss 9, Pp n/a-n/a (2021)

Abstract Recently, the gut microbiota (GM) has been shown to be a regulator of bone homeostasis and the mechanisms by which GM modulates bone mass are still being investigated. Here, it is found that colonization with GM from children (CGM) but not f

Externí odkaz: https://doaj.org/article/79bbd951f9f5421191d8bcacdee71b01

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Harmine targets inhibitor of DNA binding‐2 and activator protein‐1 to promote preosteoclast PDGF‐BB production

Autor: Yong Zhou, You-You Li, Hui Xie, Hao Yin, Zheng-Zhao Liu, Jie Huang, Yi-Yi Wang, Chun-Yuan Chen, Xiong-Ke Hu, Meng-Lu Chen, Kun Xia, Zhen-Xing Wang, Zheng-Guang Wang, Jia Cao

Publikováno v: Journal of Cellular and Molecular Medicine

Osteoporosis is one of the most common metabolic bone diseases affecting millions of people. We previously found that harmine prevents bone loss in ovariectomized mice via increasing preosteoclast platelet‐derived growth factor‐BB (PDGF‐BB) pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d870dac0fbdb71bc549a6b9e0d01f952
https://doi.org/10.1111/jcmm.16562

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Extracellular Vesicles from Akkermansia muciniphila Elicit Antitumor Immunity Against Prostate Cancer via Modulation of CD8+ T Cells and Macrophages

Autor: Ran Xu, Kun Xia, Hui Xie, Chun-Yuan Chen, Jiang-Hua Liu, Xiong-Ke Hu, Zhen-Xing Wang, Shan-Shan Rao, Zhong-Wei Luo, Yi-Wei Liu

Publikováno v: International Journal of Nanomedicine. 16:2949-2963

Zhong-Wei Luo,1,2 Kun Xia,1,2 Yi-Wei Liu,1,2 Jiang-Hua Liu,1,2 Shan-Shan Rao,2,3 Xiong-Ke Hu,1,2 Chun-Yuan Chen,1,2 Ran Xu,4 Zhen-Xing Wang,1,2 Hui Xie1,2,5– 8 1Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80229b59c68d7286b2203cdd5d193443
https://doi.org/10.2147/ijn.s304515

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Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3

Publikováno v: Autophagy

Senile osteoporosis (OP) is often concomitant with decreased autophagic activity. OPTN (optineurin), a macroautophagy/autophagy (hereinafter referred to as autophagy) receptor, is found to play a pivotal role in selective autophagy, coupling autophag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7311ca95f2653e019c163489ab951b4
https://doi.org/10.1080/15548627.2020.1839286

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Fasting before or after wound injury accelerates wound healing through the activation of pro-angiogenic SMOC1 and SCG2

Publikováno v: Theranostics

Healing of the chronic diabetic ulceration and large burns remains a clinical challenge. Therapeutic fasting has been shown to improve health. Our study tested whether fasting facilitates diabetic and burn wound healing and explored the underlying me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3dcf63d2e9936abd69e23c210bc656b
http://europepmc.org/articles/PMC7069085

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Neuronal Induction of Bone‐Fat Imbalance through Osteocyte Neuropeptide Y

Publikováno v: Advanced Science, Vol 8, Iss 24, Pp n/a-n/a (2021)
Advanced Science

A differentiation switch of bone marrow mesenchymal stem/stromal cells (BMSCs) from osteoblasts to adipocytes contributes to age‐ and menopause‐associated bone loss and marrow adiposity. Here it is found that osteocytes, the most abundant bone ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bea3b382b541cee5b3e74c2789b7ca4
https://doaj.org/article/c95444b404b64534abd3b7ebb0ee29c2

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Extracellular Vesicles from

Autor: Zhong-Wei, Luo, Kun, Xia, Yi-Wei, Liu, Jiang-Hua, Liu, Shan-Shan, Rao, Xiong-Ke, Hu, Chun-Yuan, Chen, Ran, Xu, Zhen-Xing, Wang, Hui, Xie

Publikováno v: International Journal of Nanomedicine

Purpose Prostate cancer (PCa) is one of the most common malignancies in males. Despite the success of immunotherapy in many malignant cancers, strategies are still needed to improve therapeutic efficacy in PCa. This study aimed to investigate the eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c5f87a3d66b55dcf20ce5fa7ac66d411
https://pubmed.ncbi.nlm.nih.gov/33907401

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