Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Xiomara A. Perez"'
Publikováno v:
Neurobiology of Disease, Vol 91, Iss , Pp 47-58 (2016)
L-dopa-induced dyskinesias (LIDs) are a serious complication of L-dopa therapy for Parkinson's disease. Emerging evidence indicates that the nicotinic cholinergic system plays a role in LIDs, although the pathways and mechanisms are poorly understood
Externí odkaz:
https://doaj.org/article/5a44146eb22a4d109e0dafbb5cc48753
Autor:
Maryka Quik, Archana Mallela, Matthew Chin, J. Michael McIntosh, Xiomara A. Perez, Tanuja Bordia
Publikováno v:
Neurobiology of Disease, Vol 50, Iss , Pp 30-41 (2013)
l-Dopa-induced dyskinesias (LIDs) are abnormal involuntary movements that develop with long term l-dopa therapy for Parkinson's disease. Studies show that nicotine administration reduced LIDs in several parkinsonian animal models. The present work wa
Externí odkaz:
https://doaj.org/article/401ea9edfd694718987778451cf4922b
Autor:
Amy B. Manning-Boğ, W. Michael Caudle, Xiomara A. Perez, Stephen H. Reaney, Ronald Paletzki, Martha Z. Isla, Vivian P. Chou, Alison L. McCormack, Gary W. Miller, J. William Langston, Charles R. Gerfen, Donato A. DiMonte
Publikováno v:
Neurobiology of Disease, Vol 27, Iss 2, Pp 141-150 (2007)
Mutations in the gene for DJ-1 have been associated with early-onset autosomal recessive parkinsonism. Previous studies of null DJ-1 mice have shown alterations in striatal dopamine (DA) transmission with no DAergic cell loss. Here we characterize a
Externí odkaz:
https://doaj.org/article/361092cdf0f14aeea0d1a41938d92889
Autor:
Erica L. Unger, David J. Eve, Xiomara A. Perez, Dawn K. Reichenbach, Yanqun Xu, Michael K. Lee, Anne M. Andrews
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 2, Pp 431-443 (2006)
Genetic and biochemical abnormalities associated with α-synuclein are implicated in the etiology of Parkinson's disease (PD). In this study, altered locomotor behavior linked to the expression of mutant or wildtype human α-synuclein was investigate
Externí odkaz:
https://doaj.org/article/4f006b12e90a44ca98aceff5367c5f68
Autor:
Brittany L. Taylor, James Ciprano, Aaron S. Goldstein, Xiomara I. Perez, Joseph W. Freeman, Chinyere Onyekachi Utaegbulam Freeman
Publikováno v:
Regen Eng Transl Med
In the USA, approximately 500,000 bone grafting procedures are performed annually to treat injured or diseased bone. Autografts and allografts are the most common treatment options but can lead to adverse outcomes such as donor site morbidity and mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfc832d1b3e3fa7e596a2997550d671
https://doi.org/10.1007/s40883-018-0084-9
https://doi.org/10.1007/s40883-018-0084-9
Autor:
Lars eDittrich, Jaime Eduardo Heiss, Deepti Ravindranath Warrier, Xiomara Andrea Perez, Maryka eQuik, Thomas Sean Kilduff
Publikováno v:
Frontiers in Neural Circuits, Vol 6 (2012)
We have previously demonstrated that Type I neuronal Nitric Oxide Synthase (nNOS)-expressing neurons are sleep-active in the cortex of mice, rats and hamsters. These neurons are known to be GABAergic, to express Neuropeptide Y and, in rats, to co-exp
Externí odkaz:
https://doaj.org/article/ee71e878c6ca4173858048e75ba2c16e
Publikováno v:
Nicotine & Tobacco Research. 21:357-369
Emerging studies indicate that striatal cholinergic interneurons play an important role in synaptic plasticity and motor control under normal physiological conditions, while their disruption may lead to movement disorders. Here we discuss the involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b969ef9160df1971ca9cd621f9c493c
https://doi.org/10.1093/ntr/nty063
https://doi.org/10.1093/ntr/nty063
Publikováno v:
Journal of Neural Transmission. 125:1251-1262
Cholinergic signaling plays a key role in regulating striatal function. The principal source of acetylcholine in the striatum are the cholinergic interneurons which, although low in number, densely arborize to modulate striatal neurotransmission. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64e5beb7deaba8717a5098550417182
https://doi.org/10.1007/s00702-018-1845-9
https://doi.org/10.1007/s00702-018-1845-9
Autor:
Xiomara I. Perez, Mollie S. Davis, Palangat Radhakrishnan, Joel Yarmush, Devasena Manchikalapati, Ileana Marrero-Berrios, Rene S. Schloss, Tim Maguire, Hattiyangangadi Kamath, Joseph SchianodiCola
Publikováno v:
Drug Delivery and Translational Research. 8:226-238
Mesenchymal stromal cell (MSC) therapies have become potential treatment options for multiple ailments and traumatic injuries. In the clinical setting, MSC are likely to be co-administered with local anesthetics (LA) which have been shown to have dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4454a5da54fb2451c11fbb3ed3b1eb36
https://doi.org/10.1007/s13346-017-0454-8
https://doi.org/10.1007/s13346-017-0454-8
Publikováno v:
Movement Disorders. 32:538-548
Background Dyskinesias are a disabling motor complication that arises with prolonged l-dopa treatment. Studies using D1 receptor drugs and genetically modified mice suggest that medium spiny neurons expressing D1 receptors play a primary role in l-do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c18eb24b2795a317f3b99200decd077a
https://doi.org/10.1002/mds.26955
https://doi.org/10.1002/mds.26955