Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Xinzhu Pu"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Doxorubicin (DOX)-induced cardiotoxicity has been widely observed, yet the specific impact on cardiac fibroblasts is not fully understood. Additionally, the modulation of the transforming growth factor beta (TGF-β) signaling pathway by DOX
Externí odkaz:
https://doaj.org/article/9dd0bbe5de2645ceafc5b8b5e1dc7056
Autor:
Cameron Skaggs, Steve Nick, Conner Patricelli, Laura Bond, Kali Woods, Luke Woodbury, Julia Thom Oxford, Xinzhu Pu
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract Objective Doxorubicin (DOX) is a highly effective chemotherapeutic used to treat many adult and pediatric cancers. However, its use is limited due to a dose-dependent cardiotoxicity, which can lead to lethal cardiomyopathy. In contrast to th
Externí odkaz:
https://doaj.org/article/46234a302fb44cf7bf5c5723a0ed518c
Publikováno v:
BMC Research Notes, Vol 17, Iss 1, Pp 1-2 (2024)
Abstract Objectives Osteoarthritis (OA) is a major concern in the United States and worldwide. Development and validation of robust decellularization techniques is critical in generating suitable bioscaffolds for future OA treatment options. Data des
Externí odkaz:
https://doaj.org/article/5d496f3281db497d92b45719197352d7
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Objective Extracellular matrix proteins play important roles in embryonic development and antibodies that specifically detect these proteins are essential to understanding their function. The zebrafish embryo is a popular model for vertebrat
Externí odkaz:
https://doaj.org/article/cd40e211117d41fd9f11a0a7b218479b
Autor:
Olga A. Mass, Joseph Tuccinardi, Luke Woodbury, Cody L. Wolf, Bri Grantham, Kelsey Holdaway, Xinzhu Pu, Matthew D. King, Don L. Warner, Cheryl L. Jorcyk, Lisa R. Warner
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Oncostatin M (OSM) is a pleiotropic, interleukin-6 family inflammatory cytokine that plays an important role in inflammatory diseases, including inflammatory bowel disease, rheumatoid arthritis, and cancer progression and metastasis. Recentl
Externí odkaz:
https://doaj.org/article/9d8f0adf525449bc92eb3e4f5ff6c2f0
Autor:
Guniz Bas, Stacie Loisate, Stephanie F. Hudon, Kali Woods, Eric J. Hayden, Xinzhu Pu, Richard Beard, Julia T. Oxford, Gunes Uzer
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract A primary component of exercise, mechanical signals, when applied in the form of low intensity vibration (LIV), increases mesenchymal stem cell (MSC) osteogenesis and proliferation. While it is generally accepted that exercise effectively co
Externí odkaz:
https://doaj.org/article/42ee66dff37e4553bb1fb6d141b96e08
Autor:
Roxanne N. Stone, Stephanie M. Frahs, Makenna J. Hardy, Akina Fujimoto, Xinzhu Pu, Cynthia Keller-Peck, Julia Thom Oxford
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6241 (2021)
Osteoarthritis is a major concern in the United States and worldwide. Current non-surgical and surgical approaches alleviate pain but show little evidence of cartilage restoration. Cell-based treatments may hold promise for the regeneration of hyalin
Externí odkaz:
https://doaj.org/article/3b928cdcd58a4f35adf18b9020656c45
Autor:
Nisha Shrestha, Sheenah L. Bryant, Christopher Thomas, Devon Richtsmeier, Xinzhu Pu, Juliette Tinker, Daniel Fologea
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The ability of pore-forming proteins to interact with various analytes has found vast applicability in single molecule sensing and characterization. In spite of their abundance in organisms from all kingdoms of life, only a few pore-forming
Externí odkaz:
https://doaj.org/article/5b75edd8d9644309bf79188984136256
Autor:
Julia Thom Oxford, Ken A. Cornell, Jared J. Romero, Diane B. Smith, Tracy L. Yarnell, Rhiannon M. Wood, Cheryl L. Jorcyk, Trevor J. Lujan, Allan R. Albig, Kristen A. Mitchell, Owen M. McDougal, Daniel Fologea, David Estrada, Juliette K. Tinker, Rajesh Nagarajan, Don L. Warner, Troy T. Rohn, Jim Browning, Richard S. Beard, Lisa R. Warner, Brad E. Morrison, Clare K. Fitzpatrick, Gunes Uzer, Laura Bond, Stephanie M. Frahs, Cynthia Keller-Peck, Xinzhu Pu, Luke G. Woodbury, Matthew W. Turner
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2141 (2020)
The Center of Biomedical Research Excellence in Matrix Biology strives to improve our understanding of extracellular matrix at molecular, cellular, tissue, and organismal levels to generate new knowledge about pathophysiology, normal development, and
Externí odkaz:
https://doaj.org/article/46a0ad2feae84ca5a20308983f1c4fb1
Autor:
Barbara A Hocevar, Lisa M Kamendulis, Xinzhu Pu, Susan M Perkins, Zheng-Yu Wang, Erica L Johnston, John M DeWitt, Lang Li, Patrick J Loehrer, James E Klaunig, E Gabriela Chiorean
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90052 (2014)
Several risk factors have been identified as potential contributors to pancreatic cancer development, including environmental and lifestyle factors, such as smoking, drinking and diet, and medical conditions such as diabetes and pancreatitis, all of
Externí odkaz:
https://doaj.org/article/64ead8c36f794c6f9d18d3b79cc723be