Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Xinyun Ji"'
Autor:
Chao Lv, Chongqing Hu, Chuanmeng Zhu, Xiaoning Wan, Chen Chen, Xinyun Ji, Yating Qin, Li Lu, Xiaomei Guo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 115963- (2024)
Autoimmune myocarditis, which falls within the broad spectrum of myocarditis, is characterized by an excessive inflammatory response in the heart, and can progress into dilated cardiomyopathy and irreversible heart failure in all possibility. However
Externí odkaz:
https://doaj.org/article/da38fe490b9247e4a21b5f51e9ed4684
Autor:
Weibin Ruan, Xinyun Ji, Yating Qin, Xinxin Zhang, Xiaoning Wan, Chuanmeng Zhu, Chao Lv, Chongqing Hu, Juan Zhou, Li Lu, Xiaomei Guo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Sepsis is a dysregulated systemic inflammatory response that often leads to cardiac dysfunction, which is termed sepsis-induced cardiomyopathy (SIC). Harmine, a natural β-carboline alkaloid compound, has been shown to exert pharmacological effects o
Externí odkaz:
https://doaj.org/article/ea8102c57ef549d0bd2bc90d332249df
Autor:
Yating Qin, Chao Lv, Xinxin Zhang, Weibin Ruan, Xiangyu Xu, Chen Chen, Xiaoning Wan, Xinyun Ji, Juan Zhou, Li Lu, Xiaomei Guo
Publikováno v:
Cardiovascular Therapeutics, Vol 2022 (2022)
Background. Doxorubicin (DOX) is one of the most potent and widely prescribed antitumor agents; however, its clinical use is limited by cardiac side effects. In this study, we aimed to clarify the protective effects of Qiliqiangxin (QL), a traditiona
Externí odkaz:
https://doaj.org/article/fec5e51e6f3b4c29b0640265c8f6fd5a
Autor:
Yating Qin, Chao Lv, Xinxin Zhang, Weibin Ruan, Xiangyu Xu, Chen Chen, Xinyun Ji, Li Lu, Xiaomei Guo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Anthracyclines, such as doxorubicin (DOX), are among the effective chemotherapeutic drugs for various malignancies. However, their clinical use is limited by irreversible cardiotoxicity. This study sought to determine the role of neuraminidase 1 (NEU
Externí odkaz:
https://doaj.org/article/5765ecfe4c1842bd875c0eadebce7f07
Autor:
Xinyun Jing, Niubing Zhang, Xiaojuan Zhou, Ping Chen, Jie Gong, Kaixiang Zhang, Xueting Wu, Wenjuan Cai, Bang-Ce Ye, Pei Hao, Guo-ping Zhao, Sheng Yang, Xuan Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The nucleosome is one of the hallmarks of eukaryotes, a dynamic platform that supports many critical functions in eukaryotic cells. Here, we engineer the in vivo assembly of the nucleosome core in the model bacterium Escherichia coli. We sho
Externí odkaz:
https://doaj.org/article/1d21efe1a6d2422f82d32a6ecbaeef53
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Obstructive sleep apnea (OSA), characterized by chronic intermittent hypoxia (CIH), is a prevalent condition that has been associated with various forms of cancer. Although some clinical studies suggest a potential link between OS
Externí odkaz:
https://doaj.org/article/d6cab5627e1844318f19ce3719f4a53a
Autor:
Xinyun Jian, Cheng Wang, Shijuan Wu, Guo Sun, Chuan Huang, Chengbing Qiu, Yuanzheng Liu, Peter F. Leadlay, Dong Liu, Zixin Deng, Fuling Zhou, Yuhui Sun
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4149-4163 (2024)
Aminoglycosides (AGs) are a class of antibiotics with a broad spectrum of activity. However, their use is limited by safety concerns associated with nephrotoxicity and ototoxicity, as well as drug resistance. To address these issues, semi-synthetic a
Externí odkaz:
https://doaj.org/article/3c9d502866b64bac866eccc70201f248
Autor:
Weibin, Ruan, Xinyun, Ji, Yating, Qin, Xinxin, Zhang, Xiaoning, Wan, Chuanmeng, Zhu, Chao, Lv, Chongqing, Hu, Juan, Zhou, Li, Lu, Xiaomei, Guo
Publikováno v:
Frontiers in Cell and Developmental Biology
Sepsis is a dysregulated systemic inflammatory response that often leads to cardiac dysfunction, which is termed sepsis-induced cardiomyopathy (SIC). Harmine, a natural β-carboline alkaloid compound, has been shown to exert pharmacological effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85225a6d7f90d1c18e4adea197b442af
https://pubmed.ncbi.nlm.nih.gov/35111758
https://pubmed.ncbi.nlm.nih.gov/35111758
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionCongenital disorders of glycosylation (CDG) refer to monogenetic diseases characterized by defective glycosylation of proteins or lipids causing multi-organ disorders. Here, we investigate the clinical features and genetic variants of SSR
Externí odkaz:
https://doaj.org/article/b7ba56e2940e42c083ddfa5d1bd5c69a
Autor:
Longxian Chen, Liang Ou, Xinyun Jing, Yimeng Kong, Bingran Xie, Niubing Zhang, Han Shi, Hang Qin, Xuan Li, Pei Hao
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Single-molecule detection and phasing of A-to-I RNA editing events remain an unresolved problem. Long-read and PCR-free nanopore native RNA sequencing offers a great opportunity for direct RNA editing detection. Here, we develop a neural net
Externí odkaz:
https://doaj.org/article/a401690c88e74036bc88f44bac80f1d9