Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Xinyu Von Buttlar"'
Autor:
Alexandra D’Oto, Jie Fang, Hongjian Jin, Beisi Xu, Shivendra Singh, Anoushka Mullasseril, Victoria Jones, Ahmed Abu-Zaid, Xinyu von Buttlar, Bailey Cooke, Dongli Hu, Jason Shohet, Andrew J. Murphy, Andrew M. Davidoff, Jun Yang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The histone demethylase KDM6B is reported to be essential for neuroblastoma cell survival. Here the authors show that KDM6B regulates CDK4/6-pRB-E2F pathway through H3K27me3-dependent enhancer-promoter interactions in neuroblastoma.
Externí odkaz:
https://doaj.org/article/2ad9ab2b23fe41648721a58a68144d5b
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 6, Pp 100179- (2021)
Osimertinib, a third-generation EGFR tyrosine kinase inhibitor, is the preferred frontline therapy for EGFR-mutant advanced NSCLC. However, despite its high initial response rates, multiple EGFR-independent mechanisms of resistance have been reported
Externí odkaz:
https://doaj.org/article/3fd1b14909ff4b49bc19c48805063e42
Autor:
Kelsey Poorman, John Y. Hu, Sushma Jonna, Stephen V. Liu, Xinyu von Buttlar, Ari M. Vanderwalde, Jorge Nieva, Michelle Saul
Publikováno v:
Transl Lung Cancer Res
Background Higher tumor mutation burden (TMB) in advanced non-small cell lung cancer (NSCLC) is associated with superior outcomes with checkpoint inhibitor therapy. Tissue samples subject to TMB analysis may be acquired after DNA-damaging therapies s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd685da253d4a305e1ff25f9cbbcfe7
https://doi.org/10.21037/tlcr-20-1076
https://doi.org/10.21037/tlcr-20-1076
Autor:
Andrew J. Murphy, Jason M. Shohet, Alexandra D’Oto, Dongli Hu, Xinyu von Buttlar, Andrew M. Davidoff, Beisi Xu, Bailey Cooke, Jun J. Yang, Shivendra V. Singh, Victoria Jones, Anoushka Mullasseril, Hongjian Jin, Jie Fang, Ahmed Abu-Zaid
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
The H3K27me2/me3 histone demethylase KDM6B is essential to neuroblastoma cell survival. However, the mechanism of KDM6B action remains poorly defined. We demonstrate that inhibition of KDM6B activity 1) reduces the chromatin accessibility of E2F targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da49739893ca1a7c26cbefa1e9542786
https://doi.org/10.1038/s41467-021-27502-2
https://doi.org/10.1038/s41467-021-27502-2
Publikováno v:
JTO Clinical and Research Reports
JTO Clinical and Research Reports, Vol 2, Iss 6, Pp 100179-(2021)
JTO Clinical and Research Reports, Vol 2, Iss 6, Pp 100179-(2021)
Osimertinib, a third-generation EGFR tyrosine kinase inhibitor, is the preferred frontline therapy for EGFR-mutant advanced NSCLC. However, despite its high initial response rates, multiple EGFR-independent mechanisms of resistance have been reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb5c302e462ad4b68459790d42368c9
http://europepmc.org/articles/PMC8474351
http://europepmc.org/articles/PMC8474351
Publikováno v:
Journal of Emergency and Critical Care Medicine. 6:7-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca928145b8e056877e20a1cfc02f637a
https://doi.org/10.21037/jeccm-20-139
https://doi.org/10.21037/jeccm-20-139
Autor:
Camille H. Boustani, Xinyu Von Buttlar, Jacob Zaemes, Neil Sarna, Duncan Moore, Banafsheh Motazedi
Publikováno v:
American Journal of Gastroenterology. 115:S771-S772
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05235e126ac592b816f9496630f474c2
https://doi.org/10.14309/01.ajg.0000708152.19975.91
https://doi.org/10.14309/01.ajg.0000708152.19975.91
Autor:
Sue C. Kaste, Matthew J. Krasin, Monika L. Metzger, Xinyu von Buttlar, Jamie E. Flerlage, Brandon M. Triplett
Publikováno v:
Pediatric bloodcancerREFERENCES. 66(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2954becb8b14564a4f8abf0f528dfa4
https://pubmed.ncbi.nlm.nih.gov/31429511
https://pubmed.ncbi.nlm.nih.gov/31429511
Autor:
Jorge Nieva, Stephen V. Liu, John Y. Hu, Sushma Jonna, Xinyu von Buttlar, Ari M. Vanderwalde, Michelle Saul, Kelsey Poorman
Publikováno v:
Journal of Clinical Oncology. 37:2627-2627
2627 Background: Higher non-synonymous tumor mutation burden (TMB) in non-small cell lung cancer (NSCLC) is associated with a higher likelihood of response to checkpoint inhibitors. Tissue samples subject to TMB analysis may be obtained after exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75154d21640be73ebd29277371de628b
https://doi.org/10.1200/jco.2019.37.15_suppl.2627
https://doi.org/10.1200/jco.2019.37.15_suppl.2627
Autor:
Nobel Del Mar, Natalie H. Guley, Anton Reiner, Xinyu von Buttlar, Marcia G. Honig, Angela S. Yu
Publikováno v:
Experimental neurology. 271
Diffuse axonal injury is thought to be the basis of the functional impairments stemming from mild traumatic brain injury. To examine how axons are damaged by traumatic events, such as motor vehicle accidents, falls, sports activities, or explosive bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a701626c9ceccf2ac79f6290a52ea26
https://pubmed.ncbi.nlm.nih.gov/25957630
https://pubmed.ncbi.nlm.nih.gov/25957630