Zobrazeno 1 - 10
of 1 046
pro vyhledávání: '"Xinyi, Chen"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Hepatocellular carcinoma (HCC), a prevalent primary malignant tumor, is notorious for its high mortality rate. Despite advancements in HCC treatment, patient outcomes remain suboptimal. This study endeavors to assess the potential
Externí odkaz:
https://doaj.org/article/27d6424cf1cf4d75b4e2f2f97b0b8dcf
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-8 (2024)
Abstract Background Observational studies have found associations between sex hormones and metabolic syndrome(Mets), but the causal relationships remains unclear. This study utilizes univariable and multivariable Mendelian randomization (MR) to eluci
Externí odkaz:
https://doaj.org/article/9e168ebb50144b2bb3229b603a620291
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Patients with mucopolysaccharidosis (MPS) often face delayed diagnoses, limited treatment options and high healthcare costs, that may significantly affect patients' quality of life. The objective of this study was to understand me
Externí odkaz:
https://doaj.org/article/81ca5734c49249f4aba06585398e063c
Autor:
Xing Wang, Yuanyuan Liu, Qiuyan Zhao, Xin Wang, Xinyi Chen, Li Hou, Shaodan Tian, Zi-Mei Peng, Xiao-Jian Han, Tao Wang, Zhen Zhang, Fang-Fang Tou, Shan Huang, Jun Rao, Lixiao Chen, Zhi Zheng
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-15 (2024)
Abstract Paired immunoglobin-like type 2 receptor beta (PILRB) mainly plays a crucial role in regulating innate immunity, but whether PILRB is involved in cancer is poorly understood. Here, we report that PILRB potentiates the PI3K/AKT pathway to dri
Externí odkaz:
https://doaj.org/article/8e34be5d33e647fc9a572d2cdea46c5e
Autor:
Dan Luo, Xinyi Chen, Min Wang, Mengdie Zhang, Yang li, Songhua Chen, Yu Zhang, Wei Wang, Qian Wu, Yuxiao Ling, Yiqing Zhou, Kui Liu, Jianmin Jiang, Bin Chen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The spatial delays of pulmonary tuberculosis (PTB) have been less explored. In this study, a total of 151,799 notified PTB cases were included, with median patient and diagnostic delays of 15 [interquartile range (IOR), 4–35] and 2 (IOR, 0
Externí odkaz:
https://doaj.org/article/4ce08153be60434e8529ab2012464889
Autor:
Yunan Yan, Senlin Zhu, Minghui Jia, Xinyi Chen, Wenlingli Qi, Fengfei Gu, Teresa G. Valencak, Jian-Xin Liu, Hui-Zeng Sun
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Understanding biological mechanisms is fundamental for improving animal production and health to meet the growing demand for high-quality protein. As an emerging biotechnology, single-cell transcriptomics has been gradually applied in divers
Externí odkaz:
https://doaj.org/article/5579850278ad4e19bcbb4dc3e0cb7773
Publikováno v:
Shipin Kexue, Vol 45, Iss 13, Pp 138-145 (2024)
In order to explore the effects of in vitro fermentation of quinoa water insoluble dietary fiber and exogenous addition of lactic acid bacteria on the gut microbiota and short-chain fatty acids (SCFAs), fecal filtrate (FF) from healthy subjects eithe
Externí odkaz:
https://doaj.org/article/14febe8c728441c4a65597d62c449e33
Autor:
Mingyu Yao, Zhenhai Zeng, Siheng Li, Zhilin Zou, Zhongxing Chen, Xinyi Chen, Qingyi Gao, Guoli Zhao, Aodong Chen, Zheng Li, Yiran Wang, Rui Ning, Colm McAlinden, Xingtao Zhou, Jinhai Huang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Glaucoma affects approximately 80 million individuals worldwide, a condition for which current treatment options are inadequate. The primary risk factor for glaucoma is elevated intraocular pressure. Intraocular pressure is determined by the
Externí odkaz:
https://doaj.org/article/056671a822684ff79aaafdd3c9844e4c
Autor:
Beibei Jin, Xiaoying Ding, Jiamin Dai, Chen Peng, Chunyu Zhu, Qinru Wei, Xinyi Chen, Ronghui Qiang, Xiaoyi Ding, Hongxiang Du, Wenbo Deng, Xiaoqing Yang
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Recurrent spontaneous abortion (RSA) is a challenging condition that affects the health of women both physically and mentally, but its pathogenesis and treatment have yet to be studied in detail. In recent years, Wharton’s jelly
Externí odkaz:
https://doaj.org/article/82c6eec8fb054cee9d5fff5f3ca20fac
Autor:
Xinyi Chen, Yiran Guo, Ting Zhao, Jiuwei Lu, Jian Fang, Yinsheng Wang, Gang Greg Wang, Jikui Song
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Isoform 1 of DNA methyltransferase DNMT3A (DNMT3A1) specifically recognizes nucleosome monoubiquitylated at histone H2A lysine-119 (H2AK119ub1) for establishment of DNA methylation. Mis-regulation of this process may cause aberrant DNA methy
Externí odkaz:
https://doaj.org/article/f313f491cb134f9da42a75c9d183fafc