Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Xinye Han"'
Autor:
Wenhao An, Changyuan Ren, Lei Yuan, Zhiqiang Qiu, Peishen Wang, Yanwen Cheng, Zi He, Xinye Han, Shouwei Li, Yihua An
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionGliomas are the most common primary intracranial tumors, known for their high invasiveness and destructiveness. Sialic acid-binding immunoglobulin-like lectin 7 (SIGLEC7) is present in various immune cells, especially macrophages, and sig
Externí odkaz:
https://doaj.org/article/d87e15298ad34eab93074ac2b9406067
Autor:
Wenhao An, Jiajun Zhou, Zhiqiang Qiu, Peishen Wang, Xinye Han, Yanwen Cheng, Zi He, Yihua An, Shouwei Li
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAdvancements in modern medicine have extended human lifespan, but they have also led to an increase in age-related diseases such as Alzheimer’s disease (AD) and atherosclerosis (AS). Growing research evidence indicates a close connection
Externí odkaz:
https://doaj.org/article/4db8b6fc5c564106b316d785e45290e1
Autor:
Di Yu, Yingying Liang, Claudia Kim, Anbalagan Jaganathan, Donglei Ji, Xinye Han, Xuelan Yang, Yanjie Jia, Ruirui Gu, Chunyu Wang, Qiang Zhang, Ka Lung Cheung, Ming-Ming Zhou, Lei Zeng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
BRD4-NUT’s bipartite binding and activation of p300 in NUT carcinoma nucleates a feed-forward spread of histone hyperacetylation and chromatin condensation that sustains aberrant pro-proliferation gene transcription and perpetual tumor cell growth.
Externí odkaz:
https://doaj.org/article/2b92973a3af04c6f8513cfd7ec585873
Autor:
Zhiqiang Qiu, Xuanyang Bai, Xiangwen Ji, Xiang Wang, Xinye Han, Duo Wang, Fenjun Jiang, Yihua An
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Alzheimer’s disease (AD) is a common neurodegenerative disorder without an effective treatment, and results in an increasingly serious health problem. However, its pathogenesis is complex and poorly understood. Nonetheless, the exact role of dysfun
Externí odkaz:
https://doaj.org/article/142dd35841e14eb4bf75dd96beb0ac6e
Autor:
Lunyu Yang, Zhang Bin, Shi Hui, Li Rong, Benshuai You, Peipei Wu, Xinye Han, Hui Qian, Wenrong Xu
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Mesenchymal stem cells derived from human umbilical cord (hucMSCs) are considered a promising tool for regenerative medicine. circRNAs as newly discovered noncoding RNAs are involved in multiple biological processes. However, little has been known ab
Externí odkaz:
https://doaj.org/article/6daf848753d44c618a46f6e8f19e21a8
Publikováno v:
Journal of Ginseng Research, Vol 39, Iss 1, Pp 22-28 (2015)
Background: Sun ginseng (SG), a specific formulation of quality-controlled red ginseng, contains approximately equal amounts of three major ginsenosides (RK1, Rg3, and Rg5), which reportedly has antitumor-promoting activities in animal models. Method
Externí odkaz:
https://doaj.org/article/5e540aeddc14445097fd665df1b9e15f
Autor:
Li Zhao, Yiqi Wang, Anbalagan Jaganathan, Yifei Sun, Ning Ma, Ning Li, Xinye Han, Xueying Sun, Huanfa Yi, Shibo Fu, Fangbin Han, Xue Li, Kunhong Xiao, Martin J Walsh, Lei Zeng, Ming‐Ming Zhou, Ka Lung Cheung
Publikováno v:
The EMBO Journal. 42
Autor:
Di Yu, Anbalagan Jaganathan, Qi Wang, Ming-Ming Zhou, Nicolas Babault, Qiang Zhang, Chengcheng Zhao, Lei Zeng, Huanfa Yi, Yanjie Jia, Xinye Han, Xuelan Yang, Miaomiao Yu, Ruirui Gu
Publikováno v:
Nature Structural & Molecular Biology. 27:333-341
BRD4, a major tandem-bromodomain-containing transcription regulator, has two isoforms. The long isoform (BRD4L) has an extended C terminus that binds transcription cofactors, while the short isoform (BRD4S) lacks this C-terminal extension. Unlike BRD
Publikováno v:
Medicine. 102:e32945
Autor:
Fenjun, Jiang, Hui, Zhou, Yanwen, Cheng, Zi, He, Peipei, Meng, Kaizhou, Sun, Peishen, Wang, Xinye, Han, Lu, Wang, Mingbin, Yang, Ningjian, Jiang, Yang, Liu, Chunmei, Yuan, Qing, Yang, Yihua, An
Publikováno v:
Experimental Cell Research. 416:113140
Because MSC-NTF has a higher ability to secrete neurotrophic factors, it may have a greater potential than ordinary MSC in clinical applications. At present, research on MSC-NTF mainly focuses on clinical aspects, but its basic research is relatively