Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Xinyan Zhu"'
Autor:
Yu Qian, Zhengxiong Ma, Zhenmei Xu, Yaning Duan, Yangjie Xiong, Ruixue Xia, Xinyan Zhu, Zongwei Zhang, Xinyu Tian, Han Yin, Jian Liu, Jing Song, Yang Lu, Anqi Zhang, Changyou Guo, Lihua Jin, Woo Jae Kim, Jiyuan Ke, Fei Xu, Zhiwei Huang, Yuanzheng He
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract WNT signaling is fundamental in development and homeostasis, but how the Frizzled receptors (FZDs) propagate signaling remains enigmatic. Here, we present the cryo-EM structure of FZD4 engaged with the DEP domain of Dishevelled 2 (DVL2), a k
Externí odkaz:
https://doaj.org/article/1012ce2eba994bd7832db8ef1a6fb40e
Autor:
Xinyu Qu, Xiongwu Xiao, Xinyan Zhu, Zhenfeng Shao, Mi Wang, Huayi Wu, Hongkai Zhao, Jianya Gong, Deren Li
Publikováno v:
Geo-spatial Information Science, Vol 27, Iss 4, Pp 1017-1034 (2024)
Road traffic crashes are becoming thorny issues being faced worldwide. Traffic crashes are spatiotemporal events and the research on the spatiotemporal patterns and variation trends of traffic crashes has been carried out. However, the impact of buil
Externí odkaz:
https://doaj.org/article/1337dde17fba4076a15ee62e6b447ef1
Autor:
Hanchen Shen, Hongbin Wang, Jianlan Mo, Jianyu Zhang, Changhuo Xu, Feiyi Sun, Xinwen Ou, Xinyan Zhu, Lidong Du, Huaqiang Ju, Ruquan Ye, Guangfu Shi, Ryan T.K. Kwok, Jacky W.Y. Lam, Jianwei Sun, Tianfu Zhang, Shipeng Ning, Ben Zhong Tang
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 299-312 (2024)
Ultrahigh dose-rate (FLASH) radiotherapy is an emerging technology with excellent therapeutic effects and low biological toxicity. However, tumor recurrence largely impede the effectiveness of FLASH therapy. Overcoming tumor recurrence is crucial for
Externí odkaz:
https://doaj.org/article/f3b895ccb8d1429386dc260ec747833c
Autor:
Bin Li, Pengchao Ruan, Xieyu Xu, Zhangxing He, Xinyan Zhu, Liang Pan, Ziyu Peng, Yangyang Liu, Peng Zhou, Bingan Lu, Lei Dai, Jiang Zhou
Publikováno v:
Nano-Micro Letters, Vol 16, Iss 1, Pp 1-14 (2024)
Highlights A fluorinated zincophilic covalent organic framework (COF-S-F) with sulfonic acid group (-SO3H) is prepared on the surface of Zn anode, which promotes the desolvation of hydrated Zn ions and inhibits the side reactions. The highly electron
Externí odkaz:
https://doaj.org/article/7312b8c3678d440ab0f37817b21e7f43
Autor:
Jiaping Zheng, Xinyan Zhu, Guiqing Xu, Xingchen Wang, Mengyang Cao, Shusen Zhu, Rui Huang, Yu Zhou
Publikováno v:
Nutrition Journal, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background Moderate caffeine intake decreases the risk of metabolic disorders and all-cause mortality, and the mechanism may be related to its ergogenic actions. Thyroid hormones are vital in metabolic homeostasis; however, their association
Externí odkaz:
https://doaj.org/article/9d6e2c10eef040e68cf29d5a99186c3a
Autor:
Jiale Liang, Asuka Inoue, Tatsuya Ikuta, Ruixue Xia, Na Wang, Kouki Kawakami, Zhenmei Xu, Yu Qian, Xinyan Zhu, Anqi Zhang, Changyou Guo, Zhiwei Huang, Yuanzheng He
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
GPR174 is a lysophosphatidylserine (LysoPS) activated GPCR. Here, the authors report the cryo-EM structure of LysoPS-bound human GPR174 in complex with Gs protein. The study reveals how GPR174 recognizes the lipid ligand and engages Gs in a distinct
Externí odkaz:
https://doaj.org/article/691d84105e0e4cb1bd29054ee3e3403b
Publikováno v:
International Journal of Applied Earth Observations and Geoinformation, Vol 123, Iss , Pp 103472- (2023)
Road traffic safety issues pose a serious threat to urban health, and how the built environment affects traffic crashes has been hotly discussed. However, there are limitations in the selection of built environment factors according to the classic 5D
Externí odkaz:
https://doaj.org/article/7a11e92e07984fb5a2a7adf1253c2ba5
Autor:
Xinyan Zhu, Yu Qian, Xiaowan Li, Zhenmei Xu, Ruixue Xia, Na Wang, Jiale Liang, Han Yin, Anqi Zhang, Changyou Guo, Guangfu Wang, Yuanzheng He
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
aGPCRs play key roles in multiple physiological processes. Here the authors report cryo-EM structures of GPR110 in complexes with Gq, Gs, Gi, G12 and G13 protein to reveal a detailed mechanism of aGPCR activation via the tethered stalk peptide and pr
Externí odkaz:
https://doaj.org/article/857e2ebca086453f83c837a93f55f5f9
Publikováno v:
Applied Sciences, Vol 13, Iss 22, p 12192 (2023)
The magnetized zeolite with an optimized conversion rate of 53% can be readily synthesized from industrial anthracite using a water-based method. The highly porous structure of ferromagnetism zeolite demonstrates robust magnetic properties with a mag
Externí odkaz:
https://doaj.org/article/0651a5d77e1c497bb963f4655716c2b8
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
ObjectWe explored developing an internal validation model to predict the moderate to severe endoscopic activity of ulcerative colitis (UC) patients based on non-invasive or minimally-invasive parameters.MethodsUlcerative Colitis Endoscopic Index of S
Externí odkaz:
https://doaj.org/article/41d6e27731334c78869efc48ec84329a