Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Xinxing Liao"'
Autor:
Jinchao Shen, Xinxing Liao, Weijun Wu, Tao Feng, Johannes Karges, Mingwei Lin, Hongjie Luo, Yu Chen, Hui Chao
Publikováno v:
Inorganic Chemistry Frontiers. 9:4171-4183
Synthesis and in-depth biological evaluation of IrCOOH–CaCO3@PEG for acidic microenvironment responsive and luminescence-guided combined Ca2+ overload and two-photon photodynamic therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdb7a21a60e8a244dc7e9d4c699729fe
https://doi.org/10.1039/d2qi00951j
https://doi.org/10.1039/d2qi00951j
Publikováno v:
Analytical Chemistry. 93:8062-8070
Peroxynitrite (ONOO-) and glutathione (GSH), two unique reactive species, play an essential regulating role in the oxidation and antioxidation in the living body and are closely associated with various physiological and pathological processes, like c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3c2562d6c74a46602964dabf95f3a8a
https://doi.org/10.1021/acs.analchem.1c01409
https://doi.org/10.1021/acs.analchem.1c01409
Autor:
Thomas W. Rees, Ruilin Guan, Xinxing Liao, Hui Chao, Liang-Nian Ji, Lina Xie, Kai Xiong, Li-Li Wang, Yu Chen
Publikováno v:
Angewandte Chemie International Edition. 60:4657-4665
Immunogenic cell death (ICD) is a vital component of therapeutically induced anti-tumor immunity. An iridium(III) complex (Ir1), containing an N,N-bis(2-chloroethyl)-azane derivate, as an endoplasmic reticulum-localized ICD inducer for non-small cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b471e40bfbf6a1fbc7ffc99929dc32
https://doi.org/10.1002/anie.202013987
https://doi.org/10.1002/anie.202013987
Publikováno v:
Chemical Communications. 57:4408-4411
We developed the first Ru(ii) complex-based bioorthogonal two-photon photosensitizers. Through bioorthogonal labelling, they realize effective tumour-specific photodynamic therapy against triple-negative breast cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32883cc51f2044c29b8fd630e2d9f6dc
https://doi.org/10.1039/d1cc00661d
https://doi.org/10.1039/d1cc00661d
Autor:
Zhou Liu, Liang-Nian Ji, Thomas W. Rees, Xinxing Liao, Libing Ke, Yu Chen, Shi Kuang, Hui Chao, Fangmian Wei
Publikováno v:
Nanoscale. 13:7590-7599
Photodynamic therapy (PDT) is a promising noninvasive cancer treatment. PDT in the clinic faces several hurdles due to the unique tumor environment, a feature of which is high levels of glutathione (GSH). An excess amount of GSH consumes reactive oxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e102e32930da8c689f57d4a0b006d02
https://doi.org/10.1039/d1nr00773d
https://doi.org/10.1039/d1nr00773d
Publikováno v:
Dalton Transactions. 50:14332-14341
Photodynamic therapy (PDT) provides an alternative option to root out localized triple-negative breast cancer (TNBC) and has been experiencing a surge of research interest over recent years. In this study, we put forward a paradigm of designing novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5d8031971a84bd7b95ee5c17404f69
https://doi.org/10.1039/d1dt01460a
https://doi.org/10.1039/d1dt01460a
Autor:
Johannes Karges, Zilong Tang, Jinchao Shen, Shi Kuang, Mingwei Lin, Weijun Wu, Hui Chao, Xinxing Liao
Publikováno v:
Inorganic Chemistry Frontiers. 8:5045-5053
High amounts of glutathione in tumour cells are able to decrease the effectiveness of cancer treatments by capturing the therapeutically necessary reactive oxygen species during the photodynamic therapy (PDT) process. In addition, many photosensitize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7eb5a26707748e9c6f627a89eb1d832
https://doi.org/10.1039/d1qi01038g
https://doi.org/10.1039/d1qi01038g
Autor:
Thomas W. Rees, Yu Chen, Shi Kuang, Liang-Nian Ji, Xiting Zhang, Leli Zeng, Lingli Sun, Xianrui Zhang, Xinxing Liao, Hui Chao
Publikováno v:
Angewandte Chemie International Edition. 59:20697-20703
The efficacy of photodynamic therapy is typically reliant on the local concentration and diffusion of oxygen. Due to the hypoxic microenvironment found in solid tumors, oxygen-independent photosensitizers are in great demand for cancer therapy. We he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b325c51e7c9ed998ed786848986b7e20
https://doi.org/10.1002/anie.202009888
https://doi.org/10.1002/anie.202009888
Autor:
Shi Kuang, Lingli Sun, Xianrui Zhang, Xinxing Liao, Thomas W. Rees, Leli Zeng, Yu Chen, Xiting Zhang, Liangnian Ji, Hui Chao
Publikováno v:
Angewandte Chemie. 132:20878-20884
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05a8704497aaaddd1ffe31b67e148398
https://doi.org/10.1002/ange.202009888
https://doi.org/10.1002/ange.202009888
Autor:
Liting He, Jian Wan, Hui Chao, Thomas W. Rees, Yi-Xian Yuan, Liang-Nian Ji, Chen Qian, Lin Wei, Yu Chen, Kai Xiong, Xinxing Liao
Publikováno v:
Angewandte Chemie International Edition. 59:16631-16637
Inducing necroptosis in cancer cells is an effective approach to circumvent drug-resistance. Metal-based triggers have, however, rarely been reported. Ruthenium(II) complexes containing 1,1-(pyrazin-2-yl)pyreno[4,5-e][1,2,4]triazine were developed wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b91aae1e2de953baae14e56a0739741
https://doi.org/10.1002/anie.202006089
https://doi.org/10.1002/anie.202006089