Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Xinxia Zhu"'
Autor:
Guangzhen Shi, Xinxia Zhu
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Cold is a significant limiting factor in productivity, particularly in northwestern and eastern China. Calcium-Dependent Protein Kinases (CDPKs), a primary calcium signaling sensor in plants, play an important role in their respon
Externí odkaz:
https://doaj.org/article/da2199f01bbc4622b6ed0420dfd141fa
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Calcium-Dependent Protein Kinases (CDPKs) are a class of serine/threonine protein kinases encoded by several gene families that play key roles in biotic and abiotic stresses response and plant growth and development. However, snow lotus (Saussurea in
Externí odkaz:
https://doaj.org/article/4e7f8aa544c441dcaa6a5e9f101a425a
Autor:
Xinxia Zhu, Brennan Olson, Dove Keith, Mason A Norgard, Peter R Levasseur, Parham Diba, Sara Protzek, Ju Li, Xiaolin Li, Tetiana Korzun, Ariana L Sattler, Abigail C Buenafe, Aaron J Grossberg, Daniel L Marks
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102129- (2024)
Background: The prognosis of pancreatic ductal adenocarcinomas (PDAC) remains very poor, emphasizing the critical importance of early detection, where biomarkers offer unique potential. Although growth differentiation factor 15 (GDF15) and Lipocalin
Externí odkaz:
https://doaj.org/article/c0b34edd40a14527bc1bb7e7e9b8b454
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Saussurea involucrata (Sik.) is alpine plant that have developed special adaptive mechanisms to resist adverse environmental conditions such as low temperature chilling during long-term adaptation and evolution. Exploring the chan
Externí odkaz:
https://doaj.org/article/bb906113ed1343efb14869da744f3017
Autor:
Xiaolin Li, Tosca Holtrop, Fleur A.C. Jansen, Brennan Olson, Pete Levasseur, Xinxia Zhu, Mieke Poland, Winni Schalwijk, Renger F. Witkamp, Daniel L. Marks, Klaske vanNorren
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 6, Pp 3014-3027 (2022)
Abstract Background Cachexia‐anorexia syndrome is a complex metabolic condition characterized by skeletal muscle wasting, reduced food intake and prominent involvement of systemic and central inflammation. Here, the gut barrier function was investi
Externí odkaz:
https://doaj.org/article/29f9d48912b94de994b5625095893167
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1312-1332 (2021)
Abstract Background Cancer cachexia is a metabolic disorder characterized by the progressive loss of fat and lean mass that results in significant wasting, ultimately leading to reduced quality of life and increased mortality. Effective therapies for
Externí odkaz:
https://doaj.org/article/0be0168948f74cdf9a0d0b4c5f5d23ee
Autor:
Brennan Olson, Xinxia Zhu, Mason A. Norgard, Peter R. Levasseur, John T. Butler, Abigail Buenafe, Kevin G. Burfeind, Katherine A. Michaelis, Katherine R. Pelz, Heike Mendez, Jared Edwards, Stephanie M. Krasnow, Aaron J. Grossberg, Daniel L. Marks
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Lipocalin 2 (LCN2) has been recently identified as an endogenous regulator of appetite. Here, using pancreatic cancer as a model of cachexia, the authors demonstrate that LCN2 is a critical mediator of cancer-associated anorexia and may be therapeuti
Externí odkaz:
https://doaj.org/article/abf8c7f4da7a45d4af0d1631fd583659
Autor:
Guangzhen Shi, Xinxia Zhu
Publikováno v:
PeerJ, Vol 10, p e12883 (2022)
Background Calcium dependent protein kinases (CDPKs) are a class of important calcium signal sensing response proteins, which play an important regulatory role in response to abiotic stress. However, researchers have not been excavated CDPKs’ role
Externí odkaz:
https://doaj.org/article/dae84f1421de4ef48fdfe6e3e4d53517
Autor:
Katherine A. Michaelis, Mason A. Norgard, Xinxia Zhu, Peter R. Levasseur, Shamilene Sivagnanam, Shannon M. Liudahl, Kevin G. Burfeind, Brennan Olson, Katherine R. Pelz, Diana M. Angeles Ramos, H. Carlo Maurer, Kenneth P. Olive, Lisa M. Coussens, Terry K. Morgan, Daniel L. Marks
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
In the treatment of pancreatic ductal adenocarcinoma (PDAC), comorbidities such as cachexia limit quality of life and survival. Here, the authors show TLR7/8 agonist R848 remodels host and tumour immune responses, promoting survival and attenuating c
Externí odkaz:
https://doaj.org/article/32ad424ed67248b39855a6f6ea030e5f
Autor:
Xinxia Zhu, Kevin G. Burfeind, Katherine A. Michaelis, Theodore P. Braun, Brennan Olson, Katherine R. Pelz, Terry K. Morgan, Daniel L. Marks
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 2, Pp 378-390 (2019)
Abstract Background Up to 80% of pancreatic cancer patients suffer from cachexia, a devastating condition that exacerbates underlying disease, reduces quality of life, and increases treatment complications and mortality. Tumour‐induced inflammation
Externí odkaz:
https://doaj.org/article/f7d21eb0c8d0469eb60e37d9204f3ebe