Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Xinwei Ge"'
Publikováno v:
Journal of Fungi, Vol 9, Iss 4, p 478 (2023)
Fusarium oxysporum f. sp. cubense tropical race 4 (Foc TR4) causes Fusarium wilt of banana, necessitating urgent measures to control this disease. However, the molecular mechanisms underlying Foc TR4 virulence remain elusive. Phosphomannose isomerase
Externí odkaz:
https://doaj.org/article/9e9a06850b11456a95d58ae3d1316929
Publikováno v:
Wireless Networks. 28:3293-3304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d521e4dfab139c3d05ef994d250aab20
https://doi.org/10.1007/s11276-022-03054-1
https://doi.org/10.1007/s11276-022-03054-1
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1860:1687-1697
Accumulating evidence suggests that soluble oligomers are more toxic than final fibrils of amyloid aggregations. Among the mixture of inter-converting intermediates with continuous distribution of sizes and secondary structures, oligomers in the β-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89e360af720e9a7d77420c1d4d0cb4a
https://doi.org/10.1016/j.bbamem.2018.03.011
https://doi.org/10.1016/j.bbamem.2018.03.011
Autor:
Emily H. Pilkington, Bo Wang, Marc-Antonie Sani, Michael Whittaker, Thomas P. Davis, Xinwei Ge, Feng Ding, May Lai, William J Stanley, Pu Chun Ke, John Jf Quinn, Aleksandr Kakinen, Esteban Nicolas Gurzov, Miaoyi Wang
Publikováno v:
Biomacromolecules
Protein aggregation into amyloid fibrils is a ubiquitous phenomenon across the spectrum of neurodegenerative disorders and type 2 diabetes. A common strategy against amyloidogenesis is to minimize the populations of toxic oligomers and protofibrils b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0c9fe281e89412eafb64924900a6b0
http://europepmc.org/articles/PMC5729549
http://europepmc.org/articles/PMC5729549
Autor:
Thomas P. Davis, Xinwei Ge, Feng Ding, Wen Yang, Praveen Govindan-Nedumpully, Emily H. Pilkington, Frances Separovic, Lokman Pang, Esteban Nicolas Gurzov, Aleksandr Kakinen, Pu Chun Ke, Pengyu Chen
Publikováno v:
Chem. Commun.. 53:9394-9397
Aggregation of the highly amyloidogenic IAPP is endogenously inhibited inside beta-cell granules at millimolar concentrations. Combining in vitro experiments and computer simulations, we demonstrated that the stabilization of IAPP upon the formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22da54ca7981bb7e0a43e8f338d89811
https://doi.org/10.1039/c7cc04291d
https://doi.org/10.1039/c7cc04291d
Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding
Autor:
Feng Ding, Thomas P. Davis, Emily H. Pilkington, Xinwei Ge, Pu Chun Ke, Bo Wang, Michael R. Whittaker, John F. Quinn, Aleksandr Kakinen, Thomas Blin
Publikováno v:
Polymer Chemistry. 7:6875-6879
To provide a molecular insight for guiding polymer coating in surface science and nanotechnology, here we examined the structures of brushed polyethylene glycol(bPEG)- and phosphorylcholine(bPC)-grafted iron oxide nanoparticles and analyzed their pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5260d6ca1d69c8723c99f1f827af62dd
https://doi.org/10.1039/c6py01480a
https://doi.org/10.1039/c6py01480a
Autor:
Feng Ding, Jozef Adamcik, Pu Chun Ke, Aleksandr Kakinen, Raffaele Mezzenga, Thomas P. Davis, Xinwei Ge, Bo Wang
Publikováno v:
Nano research. 11(7)
Understanding how small molecules interface with amyloid fibrils at the nanoscale is of importance for developing therapeutic treatments against amyloid-based diseases. Here, we show for the first time that human islet amyloid polypeptides (IAPP) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9828b461d0a7256762acc08658679199
https://pubmed.ncbi.nlm.nih.gov/30275931
https://pubmed.ncbi.nlm.nih.gov/30275931
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Oligomers populated during the early amyloid aggregation process are more toxic than mature fibrils, but pinpointing the exact toxic species among highly dynamic and heterogeneous aggregation intermediates remains a major challenge. β-barrel oligome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a29100c1ff3f4b58f51c7943d1037ee
https://doi.org/10.1038/s41598-018-28649-7
https://doi.org/10.1038/s41598-018-28649-7
Amyloid aggregation of amyloid-beta (Aβ) and islet amyloid polypeptide (IAPP) is associated with Alzheimer’s disease (AD) and type-2 diabetes (T2D), respectively. With T2D being the risk factor for AD and the ability of IAPP to cross the blood-bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd30d041ecb632820212197302f3dea9
https://europepmc.org/articles/PMC5955824/
https://europepmc.org/articles/PMC5955824/
Publikováno v:
Small. 11:4894-4899
It has been under debate if a self-assembled monolayer (SAM) with two immiscible ligands of different chain lengths and/or bulkiness can form a stripe-like pattern on a nanoparticle (NP) surface. The entropic gain upon such pattern formation due to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ffc63c4fff67e04b45171d6479e208
https://doi.org/10.1002/smll.201501049
https://doi.org/10.1002/smll.201501049