Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Xinrui L. Zhang"'
Publikováno v:
eLife, Vol 11 (2022)
Assembly of transcriptomes encoding unique neuronal identities requires selective accessibility of transcription factors to cis-regulatory sequences in nucleosome-embedded postmitotic chromatin. Yet, the mechanisms controlling postmitotic neuronal ch
Externí odkaz:
https://doaj.org/article/d46b42c268714194bf35b12e734bcfbc
Autor:
Meagan M. Kitt, Nobuko Tabuchi, W. Clay Spencer, Heath L. Robinson, Xinrui L. Zhang, Brent A. Eastman, Katherine J. Lobur, Jerry Silver, Lin Mei, Evan S. Deneris
Publikováno v:
Cell reports. 39(3)
Neurons must function for decades of life, but how these non-dividing cells are preserved is poorly understood. Using mouse serotonin (5-HT) neurons as a model, we report an adult-stage transcriptional program specialized to ensure the preservation o