Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Xinren Yu"'
Autor:
Xinren Yu, Karen A. Panckeri, Lacramioara Ivanciu, Rodney M. Camire, Carmen H. Coxon, Adam Cuker, Scott L. Diamond
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 1, Pp 54-63 (2020)
Abstract Background Microfluidic clotting assays permit drug action studies for hemophilia therapeutics under flow. However, limited availability of patient samples and Inter‐donor variability limit the application of such assays, especially with m
Externí odkaz:
https://doaj.org/article/71da544d77aa43e085358a8ca40dc390
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Microfluidic thrombosis assays allow the control of anticoagulation, hemodynamics, pharmacology, and procoagulant surfaces containing collagen ± tissue factor (TF). With corn trypsin inhibitor (CTI) ranging from low (1–4 μg/mL) to high levels (40
Externí odkaz:
https://doaj.org/article/1bd4e7d44bfe43beb44e566e8e82f7ed
Autor:
Zihan Hu1, Xinren Yu1, Pei Chen1, Keyu Jin1, Jing Zhou2,3, Guoxiang Wang2, Jiangning Yu2, Tong Wu1, Yulong Wang3, Fuqing Lin1, Tingting Zhang1 ztt-sjtu@hotmail.com, Yun Wang2 yunwang@fudan.edu.cn, Xuan Zhao1 zhaoxuan301@tongji.edu.cn
Publikováno v:
Molecular Pain. Jan-Dec2023, Vol. 19, p1-14. 14p.
Autor:
Xinren Yu, Adele Doyle
Publikováno v:
Regenerative Engineering and Translational Medicine. 9:108-124
Purpose Cardiovascular diseases, the world’s leading cause of death, are linked to changes in tissue mechanical and material properties that affect the signaling of cells in the damaged tissue. It is hard to predict the effect of altered physical c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::118fe4ecc1b65fb8d403a6bb814c67dc
https://doi.org/10.1007/s40883-022-00264-z
https://doi.org/10.1007/s40883-022-00264-z
Autor:
Karen Panckeri, Adam Cuker, Lacramioara Ivanciu, Xinren Yu, Rodney M. Camire, Carmen H. Coxon, Scott L. Diamond
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 1, Pp 54-63 (2020)
Research and Practice in Thrombosis and Haemostasis
Research and Practice in Thrombosis and Haemostasis
Background Microfluidic clotting assays permit drug action studies for hemophilia therapeutics under flow. However, limited availability of patient samples and Inter‐donor variability limit the application of such assays, especially with many patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e96d1a9a1eb9944ac13366a54315f20
https://doaj.org/article/71da544d77aa43e085358a8ca40dc390
https://doaj.org/article/71da544d77aa43e085358a8ca40dc390
Autor:
Scott L. Diamond, Xinren Yu
Publikováno v:
Thrombosis and Haemostasis. 119:586-593
Neutrophils can release extracellular traps (NETs) in infectious, inflammatory and thrombotic diseases. NETs have been detected in deep vein thrombosis, atherothrombosis, stroke, disseminated intravascular coagulation and trauma. We have previously s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223f1f051e13997899d2977514fa768d
https://doi.org/10.1055/s-0039-1678529
https://doi.org/10.1055/s-0039-1678529
Autor:
Joseph Schmidhofer, Justin Yeh, Jacqueline Kreutzer, Vivekanand Allada, Thomas G. Diacovo, Ganga Krishnamurthy, Victor O. Morell, Xinren Yu, Diana Vargas, Julie A. Vincent, Emile A. Bacha, Hairu Zhou, Scott L. Diamond
Publikováno v:
Circulation. 142
Background: Thrombotic events contribute significantly to early mortality in neonates with CHD requiring a systemic-to-pulmonary artery shunt. However, thromboprophylaxis remains suboptimal with few pharmacological agents studied and shown to be of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c652d3169dcabac6161e1bd518f40813
https://doi.org/10.1161/circ.142.suppl_3.13384
https://doi.org/10.1161/circ.142.suppl_3.13384
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Frontiers in Medicine
Frontiers in Medicine
Microfluidic thrombosis assays allow the control of anticoagulation, hemodynamics, pharmacology, and procoagulant surfaces containing collagen ± tissue factor (TF). With corn trypsin inhibitor (CTI) ranging from low (1–4 μg/mL) to high levels (40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53448bc1e011fe5be5b6af9370b52781
https://doi.org/10.3389/fmed.2018.00209
https://doi.org/10.3389/fmed.2018.00209
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 16(2)
Essentials Neutrophil extracellular traps (NETs) are generated during thrombosis and sepsis. The effect of hemodynamics on NETosis during sterile thrombosis was studied using microfluidics. Pressure gradients > 70 mmHg per mm-clot across sterile occl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c11347973f607b1010ef19710239ba
https://pubmed.ncbi.nlm.nih.gov/29156107
https://pubmed.ncbi.nlm.nih.gov/29156107
Publikováno v:
Biomicrofluidics. 12:042201
Extreme flows can exist within pathological vessel geometries or mechanical assist devices which create complex forces and lead to thrombogenic problems associated with disease. Turbulence and boundary layer separation are difficult to obtain in micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b993cd32ba6b5b6179849416260933
https://doi.org/10.1063/1.5021769
https://doi.org/10.1063/1.5021769