Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Xinnuo Lei"'
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-15 (2024)
Abstract Duck circovirus (DuCV) is a small, nonenveloped, single-stranded DNA virus with immunosuppressive effects on ducks that leads to slow growth and elevated mortality following mixed infections. Its infection manifests as feather loss, slow gro
Externí odkaz:
https://doaj.org/article/cb992065c7d54004af87909bc2f030dc
Autor:
Xinnuo Lei, Jinzhao Ban, Zhi Wu, Shinuo Cao, Mo Zhou, Li Zhang, Rui Zhu, Huipeng Lu, Shanyuan Zhu
Publikováno v:
Veterinary Sciences, Vol 11, Iss 6, p 274 (2024)
The continuously evolving PRRSV has been plaguing pig farms worldwide for over 30 years, with conventional vaccines suffering from insufficient protection and biosecurity risks. To address these challenges, we identified 10 PRRSV-specific CTL epitope
Externí odkaz:
https://doaj.org/article/fa215afc67e54aca9a491c441fc440f4
Autor:
Hongyi Zhou, Xinnuo Lei, Tyler Benson, James Mintz, Xiaojing Xu, Ruth B. Harris, Neal L. Weintraub, Xiaoling Wang, Weiqin Chen
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 10, Pp 1912-1925 (2015)
Mutations in BSCL2/SEIPIN cause Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2), but the mechanisms whereby Bscl2 regulates adipose tissue function are unclear. Here, we generated adipose tissue (mature) Bscl2 knockout (Ad-mKO) mice, in whi
Externí odkaz:
https://doaj.org/article/c466152b19d94f8e891d7195badf1161
Autor:
Wei Wang, Leping Liu, Shiyin Guo, Yixing Qiu, Yan Qin, Yuqing Jian, Caiyun Peng, Bin Li, Yi Hu, Xinnuo Lei, Aibing Wang, Huanghe Yu
Publikováno v:
Journal of Pharmacy and Pharmacology. 73:60-69
Objectives To explore the in vivo anti-obesity effect of chikusetsusaponin V and explore the underlying mechanism by transcriptomic and metabonomic methods. Methods The physiological parameters of high-fat-diet induced obese mice administered with or
Autor:
Wanting Yu, Yang Zhan, Zhibang Deng, Xiong Cai, Hongyu Lei, Yi Yang, Yujie Sun, Naidong Wang, Xinnuo Lei, Aibing Wang
Publikováno v:
J Virol
The capsid protein (Cap) is the sole structural protein and the main antigen of porcine circovirus type 2 (PCV2). Structural loops of the Cap play crucial roles in viral genome packaging, capsid assembly, and virus-host interactions. Although the mol
Autor:
Hongyu Lei, Zhibang Deng, Naidong Wang, Xiong Cai, Yang Zhan, Wanting Yu, Aibing Wang, Xinnuo Lei, Yi Yang, Yujie Sun
Publikováno v:
J Virol
The capsid protein (Cap) is the sole structural protein and the main antigen of porcine circovirus type 2 (PCV2). Structural loops of the Cap play crucial roles in viral genome packaging, capsid assembly, and virus-host interactions. Although the mol
Publikováno v:
Expert review of vaccines. 19(3)
Introduction: Over the past two decades, virus-like particles (VLPs) have been developed as a new generation of vaccines against viral infections. Based on VLPs, chimeric VLPs (chi-VLPs) have been generated through genetic modifications or chemical c
Autor:
Huabo Su, Hongyi Zhou, Weiqin Chen, Xinnuo Lei, Todd A. Lydic, Jie Li, Neal L. Weintraub, Yun Yan
Publikováno v:
Journal of Molecular and Cellular Cardiology. 140:55
Mutations in the BSCL2 gene underlie human type 2 Berardinelli-Seip congenital lipodystrophy (BSCL2) disease. Global Bscl2(–/–) mice recapitulate human BSCL2 lipodystrophy and results in the development of insulin resistance and hypertrophic card
Autor:
Jiaxin Zhang, Yiwen Qin, Aibing Wang, Dongliang Wang, Yawen Zhou, Naidong Wang, Liu Jue, Yi Yang, Yifan Jiang, Yang Zhan, Meng Li, Xinnuo Lei
Publikováno v:
Research in veterinary science. 124
Porcine circovirus type 2 (PCV2) causes huge economic losses in the global swine industry and has a complex and poorly understood virus-host interaction mechanism. We reported that the C-terminal of the capsid protein of all PCV2 isolates shared a st
Publikováno v:
Molecular and Cellular Endocrinology. 411:207-213
Obesity and its associated morbidities represent one of the major and most rapidly expanding health epidemics in the world. Recent genome-wide association studies (GWAS) have identified several variants in LYPLAL1 gene that are significantly associat