Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Xinming, Zhuo"'
Autor:
Shravan Leonard-Murali, Chetana Bhaskarla, Ghanshyam S. Yadav, Sudeep K. Maurya, Chenna R. Galiveti, Joshua A. Tobin, Rachel J. Kann, Eishan Ashwat, Patrick S. Murphy, Anish B. Chakka, Vishal Soman, Paul G. Cantalupo, Xinming Zhuo, Gopi Vyas, Dara L. Kozak, Lindsey M. Kelly, Ed Smith, Uma R. Chandran, Yen-Michael S. Hsu, Udai S. Kammula
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Immune checkpoint inhibition has shown success in treating metastatic cutaneous melanoma but has limited efficacy against metastatic uveal melanoma, a rare variant arising from the immune privileged eye. To better understand this resistance,
Externí odkaz:
https://doaj.org/article/c3827bd8a22341ebb07936043ec06ea7
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101547- (2024)
Externí odkaz:
https://doaj.org/article/cf45864f736842fa9f66d50c9168bd6c
Autor:
Xinming Zhuo, Barry E. Knox
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract CRX and NRL are retina-specific transcription factors that control rod photoreceptor differentiation and synergistically activate rod phototransduction gene expression. Previous experiments showed they interact in vitro and in yeast two-hybr
Externí odkaz:
https://doaj.org/article/1b6a7a0c5fb949d2aa93208b32babbd4
Autor:
Dongwon Lee, Wu Chen, Heet Naresh Kaku, Xinming Zhuo, Eugene S Chao, Armand Soriano, Allen Kuncheria, Stephanie Flores, Joo Hyun Kim, Armando Rivera, Frank Rigo, Paymaan Jafar-nejad, Arthur L Beaudet, Matthew S Caudill, Mingshan Xue
Publikováno v:
eLife, Vol 12 (2023)
UBE3A encodes ubiquitin protein ligase E3A, and in neurons its expression from the paternal allele is repressed by the UBE3A antisense transcript (UBE3A-ATS). This leaves neurons susceptible to loss-of-function of maternal UBE3A. Indeed, Angelman syn
Externí odkaz:
https://doaj.org/article/aba3381792b34656adb654c46bc529f1
Autor:
Shu-qun Shi, Carrie E. Mahoney, Pavel Houdek, Wenling Zhao, Matthew P. Anderson, Xinming Zhuo, Arthur Beaudet, Alena Sumova, Thomas E. Scammell, Carl Hirschie Johnson
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Normal neurodevelopment requires precise expression of the key ubiquitin ligase gene Ube3a. Comparing newly generated mouse models for Ube3a downregulation (models of Angelman syndrome) vs. Ube3a upregulation (models for autism), we find reciprocal e
Externí odkaz:
https://doaj.org/article/b41a57afdeb4418496ca592e63b055fe
Autor:
Erica Shen, Nathan K. Leclair, Kristi Herlth, Melissa Soucy, Nick Renzette, Xinming Zhuo, Kevin Kelly, Gregory Omerza, Hilary Onyiuke, Ian McNeill, Leo Wolansky, Kevin Becker, Lei Li, Qian Wu, Ketan R. Bulsara
Publikováno v:
Acta Neurochirurgica. 165:1323-1331
Autor:
Xinming Zhuo, Qun Wang, Liesbeth Vossaert, Roseen Salman, Adriel Kim, Ignatia Van den Veyver, Amy Breman, Arthur Beaudet
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249695 (2021)
A major challenge for cell-based non-invasive prenatal testing (NIPT) is to distinguish individual presumptive fetal cells from maternal cells in female pregnancies. We have sought a rapid, robust, versatile, and low-cost next-generation sequencing m
Externí odkaz:
https://doaj.org/article/71b7afd547874f3db09b53d76f120a69
Publikováno v:
MethodsX, Vol 5, Iss , Pp 1140-1147 (2018)
Live imaging has become the favorite method in recent years to study the protein transport, localization and dynamics in live cells. Protein transport is extremely essential for proper function of photoreceptors. Aberration in the proper transport of
Externí odkaz:
https://doaj.org/article/77c21cc617ba4fc6aba57e9b375e7582
Autor:
Erin Rooney Riggs, Taylor I. Bingaman, Carrie-Ann Barry, Andrea Behlmann, Krista Bluske, Bret Bostwick, Alison Bright, Chun-An Chen, Amanda R. Clause, Avinash V. Dharmadhikari, Mythily Ganapathi, Claudia Gonzaga-Jauregui, Andrew R. Grant, Madeline Y. Hughes, Se Rin Kim, Amanda Krause, Jun Liao, Aimé Lumaka, Michelle Mah, Caitlin M. Maloney, Shruthi Mohan, Ikeoluwa A. Osei-Owusu, Emma Reble, Olivia Rennie, Juliann M. Savatt, Hermela Shimelis, Rebecca K. Siegert, Tam P. Sneddon, Courtney Thaxton, Kelly A. Toner, Kien Trung Tran, Ryan Webb, Emma H. Wilcox, Jiani Yin, Xinming Zhuo, Masa Znidarsic, Christa Lese Martin, Catalina Betancur, Jacob A.S. Vorstman, David T. Miller, Christian P. Schaaf
Publikováno v:
Genetics in Medicine
Genetics in Medicine, 2022, 24 (9), pp.1899-1908. ⟨10.1016/j.gim.2022.05.001⟩
Genetics in Medicine, 2022, 24 (9), pp.1899-1908. ⟨10.1016/j.gim.2022.05.001⟩
International audience; Purpose: Neurodevelopmental disorders (NDDs), such as intellectual disability (ID) and autism spectrum disorder (ASD), exhibit genetic and phenotypic heterogeneity, making them difficult to differentiate without a molecular di
Autor:
Xinming Zhuo, Heet Naresh Kaku, Wu Chen, Dongwon Lee, Eugene S Chao, Armand Soriano, Allen Kuncheria, Stephanie Flores, Joo Hyun Kim, Armando Rivera, Frank Rigo, Paymaan Jafar-nejad, Arthur L Beaudet, Matthew S Caudill, Mingshan Xue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4e13c3783756ca698a986118db25056
https://doi.org/10.7554/elife.81892.sa2
https://doi.org/10.7554/elife.81892.sa2