Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Xinlai Qian"'
Autor:
Yuhan Hu, Qingzu Gao, Shuai Ma, Pei Yu, Shuang Ding, Xiaofei Yao, Zheying Zhang, Shuya Lu, Manman Lu, Jinghang Zhang, Yanling Wang, Xinlai Qian, Jiateng Zhong
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-14 (2022)
Abstract FMR1, a new m6A reader, is known to be involved in the regulation of cancer progression. However, its role, regulatory mechanism, and clinical significance in colorectal cancer (CRC) are elusive. Here, we showed that FMR1 was upregulated in
Externí odkaz:
https://doaj.org/article/b60d336b207f4042a9844588cfe1c544
Autor:
Jiateng Zhong, Yu Qin, Pei Yu, Weiyue Xia, Baoru Gu, Xinlai Qian, Yuhan Hu, Wei Su, Zheying Zhang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Tumor-infiltrating immune cells are associated with prognosis and immunotherapy targets in colorectal cancer (CRC). The recently developed CIBERSORT method allows immune cell analysis by deconvolution of high-throughput data onto gene expression. In
Externí odkaz:
https://doaj.org/article/daa4af62af134701beaec6fea0dde1ac
Autor:
Guoyang He, Wei Li, Wenli Zhao, Hui Men, Qingqing Chen, Jinlong Hu, Jingyu Zhang, Huifang Zhu, Wenxin Wang, Meijing Deng, Zishan Xu, Gaoxiang Wang, Lin Zhou, Xinlai Qian, Li Liang
Publikováno v:
Cancer Science. 114:2014-2028
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e595d835f7a314f7a5ac44c38fc9a19a
https://doi.org/10.1111/cas.15739
https://doi.org/10.1111/cas.15739
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 3, Pp 1084-1094 (2018)
Background/Aims: Iron plays a fundamental role in cell biology and its concentration must be precisely regulated. It is well documented that excess iron burden contributes to the occurrence and progression of cancer. Hepcidin secreted by liver plays
Externí odkaz:
https://doaj.org/article/1df311e8ac284d91b44f6e577eb8688d
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 3, Pp 897-906 (2017)
Background/Aims: Cysteine-rich intestinal protein 1 (CRIP1), a member of the LIM/double zinc finger protein family, is abnormally expressed in several tumour types. However, few data are available on the role of CRIP1 in cancer. In the present study,
Externí odkaz:
https://doaj.org/article/5a80cd4db2f64c5fa330f09bfaec6f74
Autor:
Xiwen Xiong, Jiahui Yu, Rui Fan, Cuicui Zhang, Lin Xu, Xupeng Sun, Yanmei Huang, Qingzhi Wang, Hai-Bin Ruan, Xinlai Qian
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212523 (2019)
Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme in mammalian nicotinamide adenine dinucleotide (NAD)+ biosynthesis. Through its NAD+-biosynthetic activity, NAMPT influences the activity of NAD+-dependent enzymes, such as sirt
Externí odkaz:
https://doaj.org/article/818aa026f01c40c38cea3589ae054dd0
Publikováno v:
Experimental biology and medicine (Maywood, N.J.).
Liver diseases, including viral hepatitis, fatty liver, metabolic-associated fatty liver disease, liver cirrhosis, alcoholic liver disease, and liver neoplasms, are major global health challenges. Despite the continued development of new drugs and te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fad98675da80776cafe2fce336e2ec
https://pubmed.ncbi.nlm.nih.gov/36533576
https://pubmed.ncbi.nlm.nih.gov/36533576
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186994 (2017)
Copper, as the third most abundant transition metal ions of human, plays an essential role in the redox reaction, signal transduction, hematopoiesis, and other physiological processes. Abnormal content of copper ions in the body will cause some disea
Externí odkaz:
https://doaj.org/article/c5ce25c6652143339570a3eff234b2b5
Autor:
Huifang Zhu, Yongzhen Li, Jingyu Guo, Shuang Feng, Hong Ge, Chuansha Gu, Mengyao Wang, Ruicong Nie, Na Li, Yongxia Wang, Haijun Wang, Jiateng Zhong, Xinlai Qian, Guoyang He
Publikováno v:
Journal of proteomics.
Proteins and translationally modified proteins like phosphoproteins have essential regulatory roles in tumorigenesis. This study attempts to elucidate the dysregulated proteins driving colorectal cancer (CRC). To explore the differential proteins, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3877d603b33c621c237a0e258c81b2c5
https://pubmed.ncbi.nlm.nih.gov/36596410
https://pubmed.ncbi.nlm.nih.gov/36596410
Autor:
Guangjie He, Jing Li, Lu Yang, Chunhua Hou, Tianjun Ni, Zhijun Yang, Xinlai Qian, Changzheng Li
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148026 (2016)
Small-molecule thiols, such as cysteine (CYS) and glutathione (GSH), are essential for maintaining the cellular redox environment and play important roles in regulating various cellular physiological functions. A fluorescence probe (compound 1-Cu2+)
Externí odkaz:
https://doaj.org/article/c37bbf0592be4f0d8d9fce9b2e58110f