Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Xinjing Luo"'
Autor:
Chenghong Ni, Shiyi Zeng, Chen Zhang, Kehan Lao, Jifeng Wang, Weiwei Wang, Xuanrong Mo, Xinjing Luo
Publikováno v:
European Journal of Inflammation, Vol 19 (2021)
Objective The objective is to examine the effect of tumor necrosis factor α (TNFα) on apoptosis and proliferation of rheumatoid arthritis synovial fibroblasts (RASFs) and to elucidate the regulatory roles of Kruppel-like factor 4 (KLF4) in TNFα-in
Externí odkaz:
https://doaj.org/article/787b4bfe225840f1b7b2293207897ac6
Autor:
Donglei Wu, Xinye Wang, Shuaijun Xu, Wanjun Zhang, Shiyi Zeng, Chenghong Ni, Xinjing Luo, Guoju Lv
Publikováno v:
European Journal of Inflammation, Vol 18 (2020)
Kruppel-like factor 2 (KLF2) is associated with acute and chronic inflammation. However, the role of KLF2 in rheumatoid arthritis (RA) remains unknown. Here, we investigated the expression of KLF2 in mice with collagen-induced arthritis (CIA) to dete
Externí odkaz:
https://doaj.org/article/a0323bae016b47598dee7910cdc0797c
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Human fibroblast-like synoviocytes play a vital role in joint synovial inflammation in rheumatoid arthritis (RA). Proinflammatory cytokines induce fibroblast-like synoviocyte activation and dysfunction. The inflammatory mediator Krüppel-like factor
Externí odkaz:
https://doaj.org/article/099a269d61f64162beae37ed779d0f78
Publikováno v:
Inflammation. 46:912-924
Hypoxia and increased levels of inflammatory cytokines in the joints are characteristics of rheumatoid arthritis (RA). However, the effects of hypoxia and tumor necrosis factor-α (TNF-α) on interleukin (IL)-6 and IL-8 production on fibroblast-like
Publikováno v:
Inflammation. 40:894-903
Transforming growth factor β-activated kinase-1 (TAK1) is a key upstream kinase in cell signaling during inflammation, which regulates the expression of inflammatory mediators. Small interfering RNA (siRNA) against TAK1 offers promise as a potential
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Mediators of Inflammation
Mediators of Inflammation
Human fibroblast-like synoviocytes play a vital role in joint synovial inflammation in rheumatoid arthritis (RA). Proinflammatory cytokines induce fibroblast-like synoviocyte activation and dysfunction. The inflammatory mediator Krüppel-like factor
Publikováno v:
Biochemical and Biophysical Research Communications. 393:860-863
WD40 repeat proteins have a wide range of diverse biological functions including signal transduction, cell cycle regulation, RNA splicing, and transcription. Myocardial ischemic preconditioning up-regulated protein 2 (MIP2) is a novel member of the W
Publikováno v:
Inflammation. 32:322-332
Forkhead box protein A1 (FoxA1) is an evolutionarily conserved winged helix transcription factor with diverse regulatory functions. However, little is known about the role of FoxA1 in acute lung injury (ALI) and pulmonary cell injury. In this study,
Publikováno v:
Cell Stress and Chaperones. 14:417-425
Forkhead box protein A1 (Foxa1) is an evolutionarily conserved winged helix transcription factor that was traditionally considered to be involved in embryonic development and cell differentiation. However, little is known about the role of Foxa1 in o
Publikováno v:
Cell Stress and Chaperones. 13:365-373
It has recently been suggested that heat shock protein (Hsp) 70, an intracellular protein, can be released into the extracellular compartment and exert important immunomodulatory functions. Although elevated Hsp70 has been found in synovial fluid fro