Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Xinjie Wu"'
Autor:
Yu Lu, Hongtao Song, Tong Lu, Lunbiao Gan, Jiayu Zhang, Keying Zhang, Shiqi Lu, Xinjie Wu, Fengze Nie, Sijia Di, Donghui Han, Fa Yang, Weijun Qin, Weihong Wen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)
Background and aims Endosialin, also known as tumor endothelial marker1 or CD248, is a transmembrane glycoprotein that is mainly expressed in cancer-associated fibroblasts (CAFs) in hepatocellular carcinoma (HCC). Our previous study has found that en
Externí odkaz:
https://doaj.org/article/dcdffb3b3c16409c8b0b8a00e6623139
Autor:
Shiqi Lu, Tong Lu, Jiayu Zhang, Lunbiao Gan, Xinjie Wu, Donghui Han, Keying Zhang, Chao Xu, Shaojie Liu, Weijun Qin, Fa Yang, Weihong Wen
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Osteosarcoma (OS) is the most common malignant bone tumor with a high incidence in children and adolescents. Frequent tumor metastasis and high postoperative recurrence are the most common challenges in OS. However, detailed mecha
Externí odkaz:
https://doaj.org/article/f76b24c8f3e148b68ce3949f16d5bf5c
Autor:
Jiayu Zhang, Tong Lu, Shiqi Lu, Shuaijun Ma, Donghui Han, Keying Zhang, Chao Xu, Shaojie Liu, Lunbiao Gan, Xinjie Wu, Fa Yang, Weihong Wen, Weijun Qin
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 665-676 (2023)
Endothelial cells (ECs) play an important role in tumor progression. Currently, the main target of anti-angiogenic therapy is the vascular endothelial growth factor (VEGF) pathway. Some patients do benefit from anti-VEGF/VEGFR therapy; however, a lar
Externí odkaz:
https://doaj.org/article/111c9936d9544224bd2a4266ad60accb
Autor:
Peixu Wang, Fuqiang Gao, Wei Sun, Zirong Li, Xinjie Wu, Lijun Shi, Xin Xu, Tengqi Li, Xiaoyu Fan, Chengxin Li, Zhizhuo Li
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-8 (2022)
Abstract Background To assess the geometrical risk factors for meniscal injuries. We hypothesized that the narrowness of the intercondylar notch and the smaller tibial spine could increase the risk of meniscal injuries. Methods We retrospectively stu
Externí odkaz:
https://doaj.org/article/db4cd7330b1b416894075439d33db0ac
Publikováno v:
Journal of Orthopaedic Translation, Vol 36, Iss , Pp 44-51 (2022)
Background: The process of necroptosis mediated by tumor necrosis factor alpha (TNF-α) might play an important role in the onset and development of the osteonecrosis of the femoral head (ONFH). The dysfunctions of bone microvascular endothelial cell
Externí odkaz:
https://doaj.org/article/667fe73ce2d740f688d385ddc15bce5c
Publikováno v:
Journal of Orthopaedic Translation, Vol 36, Iss , Pp 145-151 (2022)
Background: Studies have shown that high-energy focused extracorporeal shock wave therapy (HF-ESWT) has a certain therapeutic effect on glucocorticoid-induced osteonecrosis of the femoral head (ONFH). This study aimed to observe the efficacy and safe
Externí odkaz:
https://doaj.org/article/dcb0846a645d4945bd7ed04138d7c565
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The suboptimal or protracted regeneration of injured connective tissues often results in significant dysfunction, pain, and functional disability. Despite the prevalence of the condition, few studies have been conducted which focused on biomarkers or
Externí odkaz:
https://doaj.org/article/fa8228ae02fc4132843d82d70c5d29ec
Autor:
Jiayu Zhang, Shiqi Lu, Tong Lu, Donghui Han, Keying Zhang, Lunbiao Gan, Xinjie Wu, Yu Li, Xiaolong Zhao, Zhengxuan Li, Yajie Shen, Sijun Hu, Fa Yang, Weihong Wen, Weijun Qin
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Cancer-associated fibroblasts (CAFs) promote tumor progression through extracellular matrix (ECM) remodeling and extensive communication with other cells in tumor microenvironment. However, most CAF-targeting strategies failed in clinical
Externí odkaz:
https://doaj.org/article/65ad3fe4fa73461e8e50cf74046d79e8
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Breast cancer is a heterogeneous disease whose subtypes represent different histological origins, prognoses, and therapeutic sensitivity. But there remains a strong need for more specific biomarkers and broader alternatives for personalized treatment
Externí odkaz:
https://doaj.org/article/5a6ba3be5cf242cd8018eb08ed2fc83f
Autor:
Xiao Yu Fan, Jin Hui Ma, Xinjie Wu, Xin Xu, Lijun Shi, Tengqi Li, Peixu Wang, Chengxin Li, Zhizhuo Li, Qing Yu Zhang, Wei Sun
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-8 (2021)
Abstract Background Despite the innovations in total knee arthroplasty (TKA), there is still a subset of patients who do not acquire significant relief or expected satisfaction after primary TKA. However, this subgroup of patients still gains improve
Externí odkaz:
https://doaj.org/article/8d291dfd47fe4382897a65e7b8743eeb