Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Xinhui ZHOU"'
Autor:
Huiting Liang, Xinhui Zhou, Jie Zhang, Wenyuan Xu, Yi Liu, Xinxin Wang, Yushu Hu, Renshi Xu, Xiaobing Li
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by motor neuron loss leading to muscle weakness and atrophy. Apigenin (APG), known for its antioxidant properties, holds potential as a t
Externí odkaz:
https://doaj.org/article/73f3879c1aa848f1bc0114f22d11a071
Autor:
Reid T. Powell, Amanda L. Rinkenbaugh, Lei Guo, Shirong Cai, Jiansu Shao, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Chunxiao Fu, Yuan Qi, Faiza Baameur Hancock, Jason B. White, Clifford Stephan, Peter J. Davies, Stacy Moulder, W. Fraser Symmans, Jeffrey T. Chang, Helen Piwnica-Worms
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Triple negative breast cancer (TNBC) accounts for 15–20% of breast cancer cases in the United States. Systemic neoadjuvant chemotherapy (NACT), with or without immunotherapy, is the current standard of care for patients with early-stage TN
Externí odkaz:
https://doaj.org/article/388c05310d9142b793c6b22617755d55
Publikováno v:
Future Science OA (2023)
Aim: Our research aimed to determine an optimal cutoff value and investigate the prognostic predictive function of Ki-67. Materials & methods: We retrospectively enrolled 1146 patients diagnosed with stage I–II triple-negative breast cancer. Diseas
Externí odkaz:
https://doaj.org/article/8328100232cc4c7e92efaa3133f60f18
Autor:
Weibin Ren, He Wang, Yan Du, Yan Li, Zhuo Feng, Xinhui Zhou, Guisen Kang, Qingyao Shu, Tao Guo, Huijun Guo, Lixia Yu, Wenjie Jin, Fu Yang, Jingpeng Li, Jianzhong Ma, Wenjian Li, Chaoli Xu, Xia Chen, Xiao Liu, Chenan Yang, Luxiang Liu, Libin Zhou
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Heavy ion beam (HIB) is an effective physical mutagen that has been widely used in plant mutational breeding. Systemic knowledge of the effects caused by different HIB doses at developmental and genomic levels will facilitate efficient breeding for c
Externí odkaz:
https://doaj.org/article/383eb41f46fe49ff8dd54fd18383afc2
Autor:
Abena B. Redwood, Xiaomei Zhang, Sahil B. Seth, Zhongqi Ge, Wendy E. Bindeman, Xinhui Zhou, Vidya C. Sinha, Timothy P. Heffernan, Helen Piwnica-Worms
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract The relationship between ATR/Chk1 activity and replication stress, coupled with the development of potent and tolerable inhibitors of this pathway, has led to the clinical exploration of ATR and Chk1 inhibitors (ATRi/Chk1i) as anticancer the
Externí odkaz:
https://doaj.org/article/f52fc4ae77174e23822274182d58cffc
Publikováno v:
Translational Oncology, Vol 25, Iss , Pp 101515- (2022)
Noncoding RNAs (ncRNAs) play important roles in cancer biology, providing potential targets for cancer intervention. As a new class of endogenous noncoding RNAs, circular RNAs (circRNAs) have been recently identified in cell development and function,
Externí odkaz:
https://doaj.org/article/d00a3f7f2f5a45b5bdc499b6832cd444
Autor:
Vrutant V. Shah, Aundrietta D. Duncan, Shiming Jiang, Sabrina A. Stratton, Kendra L. Allton, Clinton Yam, Abhinav Jain, Patrick M. Krause, Yue Lu, Shirong Cai, Yizheng Tu, Xinhui Zhou, Xiaomei Zhang, Yan Jiang, Christopher L. Carroll, Zhijun Kang, Bin Liu, Jianjun Shen, Mihai Gagea, Sebastian M. Manu, Lei Huo, Michael Gilcrease, Reid T. Powell, Lei Guo, Clifford Stephan, Peter J. Davies, Jan Parker-Thornburg, Guillermina Lozano, Richard R. Behringer, Helen Piwnica-Worms, Jeffrey T. Chang, Stacy L. Moulder, Michelle Craig Barton
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Human metaplastic breast cancers (MpBC) are a rare, aggressive subclass of triple-negative breast cancers. Here, the authors show over-expression of histone reader TRIM24 is sufficient to generate tumors with a molecular signature of metabolic dysfun
Externí odkaz:
https://doaj.org/article/d198e1ab2b18460f8fd9661445a6e392
Autor:
Vidya C. Sinha, Amanda L. Rinkenbaugh, Mingchu Xu, Xinhui Zhou, Xiaomei Zhang, Sabrina Jeter-Jones, Jiansu Shao, Yuan Qi, John A. Zebala, Dean Y. Maeda, Florencia McAllister, Helen Piwnica-Worms
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The classification of breast lesions as indolent or aggressive to tailor treatment is crucial. Here, the authors use single-cell transcriptomics and multiparametric imaging of a breast cancer mouse model, report distinct tumor-immune features for the
Externí odkaz:
https://doaj.org/article/edf450673bba4946ad0410cdc2344397
Publikováno v:
Polymer Testing, Vol 111, Iss , Pp 107609- (2022)
Polarized fluorescent polymers can be promisingly used for many applications. In this work, the polarized fluorescent poly[2-methoxy,5-(2′-ethylhexyloxy)-1,4-phenylene vinylene]@MOF (MEH-PPV@MOF) composites were synthesized via the direct chain-int
Externí odkaz:
https://doaj.org/article/20db9bdc6ae94810af28b8fe3a4b691e
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Small cell neuroendocrine carcinoma (SCNEC) is rare in the gynecologic tract, which has high invasive and metastatic ability. Due to the aggressive behavior and lack of treatment, patients have an extremely poor prognosis. Here we report a 66-year-ol
Externí odkaz:
https://doaj.org/article/42ec5f06785b4f8f9f50f4ce33fa34a3