Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Xinhai Ji"'
Autor:
Jiangxue Han, Shunwang Li, Weizhi Wang, Xinhai Jiang, Chao Liu, Lijuan Lei, Yining Li, Ren Sheng, Yuyan Zhang, Yexiang Wu, Jing Zhang, Yuhao Zhang, Yanni Xu, Shuyi Si
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 6, Pp 5052-5070 (2023)
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases. Silencing information regulator 1 (SIRT1) was demonstrated to modulate cholesterol and lipid metabolism in NAFLD. Here, a novel SIRT1 activator, E1231, was studied for
Externí odkaz:
https://doaj.org/article/a17c48cb06304184888c4f5e47df2c4b
Publikováno v:
Journal of Experimental Therapeutics & Oncology. 2006, Vol. 5 Issue 4, p261-272. 12p.
Autor:
Jeannette Vasquez-Vivar, Lei Yu, Sidhartha Tan, Xinhai Ji, Jennifer Whitsett, Matthew Derrick
Publikováno v:
Annals of Neurology. 66:323-331
Objective: Tetrahydrobiopterin (BH4) deficiency is one of the causes of dystonia at birth. We hypothesized that BH4 is a developmental factor determining vulnerability of the immature fetal brain to hypoxic-ischemic injury and subsequent motor defici
Autor:
Richard B. Silverman, Alexander Drobyshevsky, Lina Chen, Yirong Yang, Haitao Ji, Sidhartha Tan, Xinhai Ji, Matthew Derrick
Publikováno v:
International Journal of Developmental Neuroscience. 27:549-557
The relationship of movement between different muscle groups has not been quantified before in the newborn period. Cerebral palsy (CP), which often occurs as a result of perinatal hypoxia-ischemia (H-I), is categorized depending on clinical presentat
Autor:
Ni Li, Yan Li, Xiaowan Han, Jing Zhang, Jiangxue Han, Xinhai Jiang, Weizhi Wang, Yang Xu, Yanni Xu, Yu Fu, Shuyi Si
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Liver X receptors (LXRs) are important regulators of cholesterol metabolism and inflammatory responses. LXR agonists exhibit potently anti-inflammatory effects in macrophages, which make them beneficial to anti-atherogenic therapy. In addition to tra
Externí odkaz:
https://doaj.org/article/5277a8f8233e462d9b23c2a2ab6b7ddf
Publikováno v:
Stroke. 38
Disorders of the maternal-placental-fetal unit often results in fetal brain injury, which in turn results in one of the highest burdens of disease, because of the lifelong consequences and cost to society. Investigating hypoxia-ischemia in the perina
Publikováno v:
Journal of experimental therapeuticsoncology. 5(4)
To investigate potential synergistic interactions between bioreductive agents, either NLCQ-1 or tirapazamine (TPZ) and two alkylating chemotherapeutic drugs, and how such interactions compare in vitro and in vivo.V79 cells (in vitro studies) and the
Autor:
Sidhartha Tan, Lauren Marie Ullman, Xinhai Ji, Alice M. Wyrwicz, Matthew Derrick, Ila Englof, Frances J. Northington, Mario Enrique Zelaya, Alexander Drobyshevsky
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 27(2)
Hypertonia and postural deficits are observed in cerebral palsy and similar abnormalities are observed in postnatal rabbits after antenatal hypoxia–ischemia. To explain why some kits become hypertonic, we hypothesized that white matter injury was r
Autor:
Lauren Marie Ullman, Sidhartha Tan, Tamas Jilling, Alexander Drobyshevsky, Matthew Derrick, Xinhai Ji, Ila Englof
Publikováno v:
Scopus-Elsevier
Perinatal brain injury results in one of the highest burdens of disease in view of the lifelong consequences and is of enormous cost to society. This makes it imperative to develop better animal models that mimic the human condition. Many neurodevelo
Publikováno v:
Anticancer research. 25(3B)
4-[3- (2-Nitro-1-imidazolyl)-propylamino]-7-chloroquinoline hydrochloride (NLCQ-1) is a novel, weakly DNA-intercalating hypoxia selective cytotoxin, which significantly potentiates the antitumor effect, but not the systemic toxicity, of commonly used