Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Xingyuan Zhai"'
Autor:
Meng Zhu, Yingli Han, Tianning Gu, Rui Wang, Xiaohui Si, Delin Kong, Peng Zhao, Xiujian Wang, Jinxin Li, Xingyuan Zhai, Zebin Yu, Huan Lu, Jingyi Li, He Huang, Pengxu Qian
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114065- (2024)
Summary: Epigenetic modification shapes differentiation trajectory and regulates the exhaustion state of chimeric antigen receptor T (CAR-T) cells. Limited efficacy induced by terminal exhaustion closely ties with intrinsic transcriptional regulation
Externí odkaz:
https://doaj.org/article/4002cebb8fe3455dbdb5f59b03c63f52
Autor:
Xingyuan, Zhai, Kai, Liu, Hongkun, Fang, Quan, Zhang, Xianjun, Gao, Fang, Liu, Shangshang, Zhou, Xinming, Wang, Yujia, Niu, Yazhen, Hong, Shu-Hai, Lin, Wen-Hsien, Liu, Changchun, Xiao, Qiyuan, Li, Nengming, Xiao
Publikováno v:
Science Advances
Description
C1qbp promotes epigenetic and transcriptional regulation of effector CD8+ T cell differentiation through up-regulation of OXPHOS.
Early-activated CD8+ T cells increase both aerobic glycolysis and mitochondrial oxidative phosphor
C1qbp promotes epigenetic and transcriptional regulation of effector CD8+ T cell differentiation through up-regulation of OXPHOS.
Early-activated CD8+ T cells increase both aerobic glycolysis and mitochondrial oxidative phosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a8a84d1b04065b5b54b6de1b7b37258
https://pubmed.ncbi.nlm.nih.gov/34860557
https://pubmed.ncbi.nlm.nih.gov/34860557
Autor:
Changchun Xiao, Yujia Niu, Quan Zhang, Fang Liu, Yazhen Hong, Xingyuan Zhai, Hongkun Fang, Wen-Hsien Liu, Shu-Hai Lin, Nengming Xiao, Shangshang Zhou, Xinming Wang, Kai Liu, Xianjun Gao, Qiyuan Li
Publikováno v:
Science Advances. 7
C1qbp promotes epigenetic and transcriptional regulation of effector CD8 + T cell differentiation through up-regulation of OXPHOS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0095926bb4eba065eb3a7c01015d7ec
https://doi.org/10.1126/sciadv.abk0490
https://doi.org/10.1126/sciadv.abk0490