Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Xingyi Que"'
Publikováno v:
Circulation Research. 132
Background: Macrophage activation plays a critical role in abdominal aortic aneurysm (AAA) development. However, molecular mechanisms controlling macrophage activation and vascular inflammation in AAA remain largely unknown. The objective of the stud
Autor:
Shi-You Chen, Chenming Sun, Dunpeng Cai, Gui Zhang, Neal L. Weintraub, Xingyi Que, Ken Fujise
Publikováno v:
Circ Res
Rationale: Abdominal aortic aneurysm (AAA) is a permanent and localized dilatation of abdominal aorta with potentially fatal consequence of aortic rupture. No effective pharmacological approach has been identified to limit AAA progression and rupture
Autor:
Yuan Xiao, Xiaoyun Xie, Hong Hao, Yuqi Cui, Peter J. Cowan, Xingyi Que, Jie Tian, Zhenguo Liu, Chunlin Yang, Xin Li, Lingjuan Liu, Jia Zhang
Publikováno v:
Journal of Cellular and Molecular Medicine
Endothelial progenitor cells (EPCs) are a group of heterogeneous cells in bone marrow (BM) and blood. Ischaemia increases reactive oxygen species (ROS) production that regulates EPC number and function. The present study was conducted to determine if
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: The objective of this study is to determine the role of SPA (surfactant protein A) in vascular smooth muscle cell (SMC) phenotypic modulation and vascular remodeling. Approach and Results: PDGF-BB (Platelet-derived growth factor-BB) and se
Publikováno v:
Journal of the American College of Cardiology. 77:2837
Autor:
Xavier Aldeguer, Xingyi Que, Fotini Debonera, Emma E. Furth, Kim M. Olthoff, Jinfu Xie, Andrew E. Gelman
Publikováno v:
Journal of Surgical Research. 116:262-268
Background The molecular pathways of ischemic injury after liver transplantation are complex and difficult to dissect because of the presence of many variables. Transgenic and genetically deficient strains of mice provide ideal models for the study o
Publikováno v:
Xenotransplantation. 11:33-42
The T-cell response to xenografts is induced by direct and indirect recognition of xenoantigens. Although the importance of indirect recognition is well established in vitro, the contribution of this pathway to xenograft rejection in vivo remains to
Publikováno v:
Transplant Immunology. 11:179-185
T-cell mediated immune responses play a critical role in chronic allograft dysfunction. The complex nature of allograft rejection, particularly with respect to the vast repertoire of alloantigens and their mode of recognition by T cells, presents a m
Autor:
Xavier Aldeguer, Andrew E. Gelman, Shungo Hiroyasu, Kim M. Olthoff, Alyssa M. Krasinkas, Rebecca Taub, Fotini Debonera, Abraham Shaked, Gideon Zamir, Xingyi Que, Kellen Kovalovich
Publikováno v:
Hepatology. 35:40-48
Interleukin-6 (IL-6) is required for normal liver regeneration, but the specific cellular source of this growth factor is unknown. We investigated whether this signal originates from the resident macrophage, the Kupffer cell. Using a murine model of
Autor:
Daniel E. Cramer, Paula M. Chilton, Yiming Huang, Suzanne T. Ildstad, Mukunda B. Ray, Xingyi Que
Publikováno v:
Transplantation. 72:1907-1914
Background We previously characterized a facilitating cell (FC) in mouse marrow that enables engraftment of allogeneic hematopoietic stem cells (HSCs) without causing graft-versus-host disease (GVHD). The FC shares some cell surface molecules with T